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Specific CD45 Isoforms Regulate T Cell Ontogeny...
Journal article

Specific CD45 Isoforms Regulate T Cell Ontogeny and Are Functionally Distinct in Modifying Immune Activation

Abstract

The antigen receptor complex on the cell surface of T lymphocytes is one of the most modular signal transduction systems yet defined. This characteristic emanates from various mechanisms that promote intermolecular associations between the αβ T cell receptor and the enzymes that transduce the intracellular biological signal cascade (reviewed in 1). Among the multiple proteins that regulate cellular responses following T cell receptor (TCR) …

Authors

Marth JD; Ong CJ; Chui D

Journal

Advances in Experimental Medicine and Biology, Vol. 365, , pp. 149–166

Publisher

Springer Nature

Publication Date

1994

DOI

10.1007/978-1-4899-0987-9_16

ISSN

0065-2598