Nitriles Concept

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• A GATA2-CDC6 axis modulates androgen receptor blockade-induced senescence in prostate cancer  Journal Articles
• A phase II study of sorafenib in combination with bicalutamide in patients with chemotherapy-naive castration resistant prostate cancer  Journal Articles
• A randomized phase II efficacy and safety study of vandetanib (ZD6474) in combination with bicalutamide versus bicalutamide alone in patients with chemotherapy naïve castration-resistant prostate cancer  Journal Articles
• Adding 6 months of androgen deprivation therapy to postoperative radiotherapy for prostate cancer: a comparison of short-course versus no androgen deprivation therapy in the RADICALS-HD randomised controlled trial  Journal Articles
• Adjuvant radiation therapy, androgen deprivation, and docetaxel for high‐risk prostate cancer postprostatectomy: Results of NRG Oncology/RTOG study 0621  Journal Articles
• American Society of Clinical Oncology Technology Assessment on the Use of Aromatase Inhibitors as Adjuvant Therapy for Women With Hormone Receptor–Positive Breast Cancer: Status Report 2002  Journal Articles
• Androgens induce oxidative stress and radiation resistance in prostate cancer cells though NADPH oxidase  Journal Articles
• Androgen‐dependent regulation of medium and long chain fatty acids uptake in prostate cancer  Journal Articles
• Aromatase inhibitors in adjuvant therapy for hormone receptor positive breast cancer: A systematic review  Journal Articles
• Assessment of Quality of Life in MA.17: A Randomized, Placebo-Controlled Trial of Letrozole After 5 Years of Tamoxifen in Postmenopausal Women  Journal Articles
• Batrachotoxin, Pyrethroids, and BTG 502 Share Overlapping Binding Sites on Insect Sodium Channels  Journal Articles
• Cabazitaxel versus abiraterone or enzalutamide in poor prognosis metastatic castration-resistant prostate cancer: a multicentre, randomised, open-label, phase II trial  Journal Articles
• Chlorothalonil as a potential endocrine disruptor in male zebrafish (Danio rerio): Impact on the hypothalamus-pituitary-gonad axis and sperm quality  Journal Articles
• Clinical outcomes of ethnic minority women in MA.17: a trial of letrozole after 5 years of tamoxifen in postmenopausal women with early stage breast cancer  Journal Articles
• Cognitive effects of aromatase inhibitor therapy in peripubertal boys  Journal Articles
• Competing risks of death in women treated with adjuvant aromatase inhibitors for early breast cancer on NCIC CTG MA.27  Journal Articles
• Controlling skeletal muscle CPT-I malonyl-CoA sensitivity: the importance of AMPK-independent regulation of intermediate filaments during exercise  Journal Articles
• Cortical and trabecular bone at the radius and tibia in postmenopausal breast cancer patients: A Peripheral Quantitative Computed Tomography (pQCT) study  Journal Articles
• Cost-effectiveness of enzalutamide versus apalutamide versus androgen deprivation therapy alone for the treatment of metastatic castration-sensitive prostate cancer in Canada  Journal Articles
• Decreased epithelial barrier function evoked by exposure to metabolic stress and nonpathogenicE. coliis enhanced by TNF-α  Journal Articles
• Diels-Alder Additions as Mechanistic Probes–Interception of Silyl-Isoindenes: Organometallic Derivatives of Polyphenylated Cycloheptatrienes and Related Seven-Membered Rings  Journal Articles
• Duration of Androgen Suppression Before Radiotherapy for Localized Prostate Cancer: Radiation Therapy Oncology Group Randomized Clinical Trial 9910  Journal Articles
• Duration of androgen deprivation therapy with postoperative radiotherapy for prostate cancer: a comparison of long-course versus short-course androgen deprivation therapy in the RADICALS-HD randomised trial  Journal Articles
• ERK1 and ERK2 kinases activate hydroxyurea-induced S-phase checkpoint in MCF7 cells by mediating ATR activation  Journal Articles
• Effect of Letrozole Versus Placebo on Bone Mineral Density in Women With Primary Breast Cancer Completing 5 or More Years of Adjuvant Tamoxifen: A Companion Study to NCIC CTG MA.17  Journal Articles
• Efficacy, Toxicity, and Quality of Life in Older Women With Early-Stage Breast Cancer Treated With Letrozole or Placebo After 5 Years of Tamoxifen: NCIC CTG Intergroup Trial MA.17  Journal Articles
• Evaluating the Feasibility of Performing Window of Opportunity Trials in Breast Cancer  Journal Articles
• Examining the ability of the Cancer and Aging Research Group tool to predict toxicity in older men receiving chemotherapy or androgen‐receptor–targeted therapy for metastatic castration‐resistant prostate cancer  Journal Articles
• Exemestane Versus Anastrozole in Postmenopausal Women With Early Breast Cancer: NCIC CTG MA.27—A Randomized Controlled Phase III Trial  Journal Articles
• Exploration of BAY 11-7082 as a Potential Antibiotic  Journal Articles
• Extending Aromatase-Inhibitor Adjuvant Therapy to 10 Years  Journal Articles
• Feeding response in marine copepods as a measure of acute toxicity of four anti-sea lice pesticides  Journal Articles
• Functional characterization of estrogen receptor subtypes, ERα and ERβ, mediating vitellogenin production in the liver of rainbow trout  Journal Articles
• Genome-Wide Associations and Functional Genomic Studies of Musculoskeletal Adverse Events in Women Receiving Aromatase Inhibitors  Journal Articles
• Guanosine Protects Glial Cells Against 6-Hydroxydopamine Toxicity  Journal Articles
• Hazard assessment using an in-silico toxicity assessment of the transformation products of boscalid, pyraclostrobin, fenbuconazole and glyphosate generated by exposure to an advanced oxidative process  Journal Articles
• Heat shock protein-27 attenuates foam cell formation and atherogenesis by down-regulating scavenger receptor-A expression via NF-κB signaling  Journal Articles
• Hepatic gene expression profiling in zebrafish (Danio rerio) exposed to the fungicide chlorothalonil  Journal Articles
• High-throughput acousto-optic-tunable-filter-based time-resolved fluorescence spectrometer for optical biopsy  Journal Articles
• Impact of premenopausal status at breast cancer diagnosis in women entered on the placebo-controlled NCIC CTG MA17 trial of extended adjuvant letrozole  Journal Articles
• Inter-related in vitro effects of androgens, fatty acids and oxidative stress in prostate cancer: A mechanistic model supporting prevention strategies  Journal Articles
• Molecular basis of selective resistance of the bumblebee BiNa_v1 sodium channel to tau-fluvalinate  Journal Articles
• Novel males' capacity to disrupt early pregnancy in mice (Mus musculus) is attenuated via a chronic reduction of males' urinary 17β-estradiol  Journal Articles
• Osteoporosis therapy and outcomes for postmenopausal patients with hormone receptor–positive breast cancer: NCIC CTG MA.27  Journal Articles
• PSA declines and survival in patients with metastatic castration-resistant prostate cancer treated with enzalutamide  Journal Articles
• Patterns of Ruxolitinib Therapy Failure and Its Management in Myelofibrosis: Perspectives of the Canadian Myeloproliferative Neoplasm Group  Journal Articles
• Perivascular adipose tissue promotes vasoconstriction: the role of superoxide anion  Journal Articles
• Possible Applications for Dopaminergic Agents Following Traumatic Brain Injury: Part 2  Journal Articles
• Potentiation of long-acting β2-agonist and glucocorticoid responses in human airway epithelial cells by modulation of intracellular cAMP  Journal Articles
• Predicting the reactivity of ambidentate nucleophiles and electrophiles using a single, general-purpose, reactivity indicator  Journal Articles
• Product studies and laser flash photolysis of direct and 2,4,6-triphenylpyrylium—zeolite Y photocatalyzed degradation of fenvalerate  Journal Articles
• Prospective, Single-Arm Trial Evaluating Changes in Uptake Patterns on Prostate-Specific Membrane Antigen–Targeted ¹⁸F-DCFPyL PET/CT in Patients with Castration-Resistant Prostate Cancer Starting Abiraterone or Enzalutamide  Journal Articles
• Radiation with or without Antiandrogen Therapy in Recurrent Prostate Cancer  Journal Articles
• Randomized Trial of a Telephone-Based Weight Loss Intervention in Postmenopausal Women With Breast Cancer Receiving Letrozole: The LISA Trial  Journal Articles
• Reduction in Endometrioma Size with Three Months of Aromatase Inhibition and Progestin Add-Back  Journal Articles
• Remission of Macroglobulinemia during Anastrozole Treatment for Breast Cancer  Journal Articles
• Risk of hepatitis B virus reactivation in HBsAg-negative, anti-HBc-positive patients with myeloproliferative neoplasms treated with ruxolitinib  Journal Articles
• Rotational Symmetry of Two Pyrethroid Receptor Sites in the Mosquito Sodium Channel  Journal Articles
• Safety and efficacy findings from the open-label, multicenter, phase 3b, expanded treatment protocol study of ruxolitinib for treatment of patients with polycythemia vera who are resistant/intolerant to hydroxyurea and for whom no alternative treatments are available  Journal Articles
• Safety of enzalutamide in patients with metastatic castration‐resistant prostate cancer previously treated with docetaxel: Expanded access in North America  Journal Articles
• Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide  Journal Articles
• Systemic Therapy in Men With Metastatic Castration-Resistant Prostate Cancer: American Society of Clinical Oncology and Cancer Care Ontario Clinical Practice Guideline  Journal Articles
• The experiences of men receiving androgen deprivation treatment for prostate cancer: a qualitative study.  Journal Articles
• The impact of ruxolitinib on thrombosis in patients with polycythemia vera and myelofibrosis  Journal Articles
• Validation of a 22-Gene Genomic Classifier in Patients With Recurrent Prostate Cancer  Journal Articles