Journal article
Androgen‐dependent regulation of medium and long chain fatty acids uptake in prostate cancer
Abstract
BACKGROUND: Epidemiological and experimental studies suggest that both fatty acids and androgens have a role in the development and progression of prostate cancer (PC). Plasma membrane fatty acid binding protein (FABP(pm)) is a transporter of medium and long chain fatty acids (MCFA and LCFA) across the plasma membrane, and is identical to the mitochondrial protein aspartate aminotransferase (mAAT) that is regulated by testosterone only in …
Authors
Pinthus JH; Lu J; Bidaisee LA; Lin H; Bryskine I; Gupta RS; Singh G
Journal
The Prostate, Vol. 67, No. 12, pp. 1330–1338
Publisher
Wiley
Publication Date
September 2007
DOI
10.1002/pros.20609
ISSN
0270-4137
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdenocarcinomaAndrogen AntagonistsAndrogensAnilidesAspartate Aminotransferase, MitochondrialBlotting, WesternCell Line, TumorFatty Acid-Binding ProteinsFatty AcidsFlow CytometryHumansMaleMetriboloneMicroscopy, ConfocalNeoplasms, Hormone-DependentNitrilesOleic AcidProstatic NeoplasmsTosyl CompoundsUp-Regulation