subject area of
- A novel synthetic C-1 analogue of 7-deoxypancratistatin induces apoptosis in p53 positive and negative human colorectal cancer cells by targeting the mitochondria: enhancement of activity by tamoxifen Journal Articles
- A postmarketing surveillance evaluation of quinapril in 3742 Canadian hypertensive patients: the ACCEPT Study. Accupril Canadian Clinical Evaluation and Patient Teaching. Journal Articles
- A proposal for an extended dual descriptor: a possible solution when Frontier Molecular Orbital Theory fails Journal Articles
- A synthesis of 3-deoxydihydrolycoricidine: Refinement of a structurally minimum pancratistatin pharmacophore Journal Articles
- Actions of two dopamine derivatives at adreno- and cholinoceptors Journal Articles
- Antagonists of the serotonin receptor 5A target human breast tumor initiating cells Journal Articles
- Background illumination reduces horizontal cell receptive-field size in both normal and 6-hydroxydopamine-lesioned goldfish retinas Journal Articles
- Cancer Cell Mitochondria Targeting by Pancratistatin Analogs is Dependent on Functional Complex II and III Journal Articles
- Central-type benzodiazepine receptors mediate the antidopaminergic effect of clonazepam and melatonin in 6-hydroxydopamine lesioned rats: involvement of a GABAergic mechanism. Journal Articles
- Chronic opioids regulate KATP channel subunit Kir6.2 and carbonic anhydrase I and II expression in rat adrenal chromaffin cells via HIF-2α and protein kinase A Journal Articles
- Current Perspectives in the Pharmacological Studies of Store-Operated Ca2+ Entry Blockers. Journal Articles
- Cyclic 3’,5’-Adenosine Monophosphate Mediates Dopamine D1-Stimulated Growth Hormone Release from Goldfish Pituitary Cells Journal Articles
- Determination of albumin sorption to intraocular lenses by radiolabeling and confocal laser scanning microscopy Journal Articles
- Diazepam-Treated Female Rats Journal Articles
- Differential effects of putative protein kinase C inhibitors on contraction of rat aortic smooth muscle Journal Articles
- Distribution of PK11195 binding sites in porcine brain studied by autoradiography in vitro and by positron emission tomography Journal Articles
- Efficacy of Secretagogues in Patients With Irritable Bowel Syndrome With Constipation: Systematic Review and Network Meta-analysis Journal Articles
- Guideline for the prevention of acute chemotherapy‐induced nausea and vomiting in pediatric cancer patients: A focused update Journal Articles
- In situ recording from gut pacemaker cells Journal Articles
- Induction of Apoptotic Cell Death Specifically in Rat and Human Cancer Cells by Pancratistatin Journal Articles
- Localization of Lysozyme Sorption to Conventional and Silicone Hydrogel Contact Lenses Using Confocal Microscopy Journal Articles
- Mechanisms underlying the antidopaminergic effect of clonazepam and melatonin in striatum Journal Articles
- Modulation of Insulin-like Growth Factor (IGF)-I and IGF-Binding Protein Interactions Enhances Skeletal Muscle Regeneration and Ameliorates the Dystrophic Pathology in mdx Mice Journal Articles
- Molecular identification and functional characterization of Mdr1a in rat cholangiocytes Journal Articles
- Mutants of CHO cells resistant to the protein synthesis inhibitors, cryptopleurine and tylocrebrine: genetic and biochemical evidence for common site of action of emetine, cryptopleurine, tylocrebrine, and tubulosine Journal Articles
- PK 11195 blockade of benzodiazepine‐induced inhibition of forskolin‐stimulated adenylate cyclase activity in the striatum Journal Articles
- PLANT ALKALOID TETRANDRINE AND ITS ANALOG BLOCK CD28-COSTIMULATED ACTIVITIES OF HUMAN PERIPHERAL BLOOD T CELLS Journal Articles
- Pancratistatin Selectively Targets Cancer Cell Mitochondria and Reduces Growth of Human Colon Tumor Xenografts Journal Articles
- Pancratistatin causes early activation of caspase-3 and the flipping of phosphatidyl serine followed by rapid apoptosis specifically in human lymphoma cells Journal Articles
- Pancratistatin induces apoptosis and autophagy in metastatic prostate cancer cells Journal Articles
- Pancratistatin: A natural anti-cancer compound that targets mitochondria specifically in cancer cells to induce apoptosis Journal Articles
- Potent and selective inhibition of human cytochrome P450 3A4 by seco-pancratistatin structural analogs Journal Articles
- Regulation of plasminogen activator inhibitor‐1 secretion by urokinase and tissue plasminogen activator in rat epithelioid‐type smooth muscle cells Journal Articles
- Relaxin alters cardiac myofilament function through a PKC-dependent pathway Journal Articles
- Selective cytochrome P450 3A4 inhibitory activity of Amaryllidaceae alkaloids Journal Articles
- Sensitivity to protein kinase C inhibitors of nicardipine‐insensitive component of high K+ contracture in rat and guinea‐pig aorta Journal Articles
- Sensitization of human melanoma cells by tamoxifen to apoptosis induction by pancratistatin, a nongenotoxic natural compound Journal Articles
- Strategies and Synthetic Methods Directed Toward the Preparation of Libraries of Substituted Isoquinolines Journal Articles
- Structural determinants responsible for the biological activity of (-)-emetine, (-)-cryptopleurine, and (-)-tylocrebrine: structure-activity relationship among related compounds. Journal Articles
- Structure–activity studies on seco-pancratistatin analogs: Potent inhibitors of human cytochrome P450 3A4 Journal Articles
- Studies directed towards the refinement of the pancratistatin cytotoxic pharmacophore Journal Articles
- Synergy of pancratistatin and tamoxifen on breast cancer cells in inducing apoptosis by targeting mitochondria Journal Articles
- Synthesis and Biological Evaluation of Fully Functionalized seco-Pancratistatin Analogues Journal Articles
- The chemosensitizing potential of GF120918 is independent of the magnitude of P-glycoprotein-mediated resistance to conventional chemotherapeutic agents in a small cell lung cancer line. Journal Articles
- Up‐regulation of PK11195 binding in areas of axonal degeneration coincides with early microglial activation in mouse brain Journal Articles