Conserved Sequence Concept

subject area of

• A Multiplex Human Syndrome Implicates a Key Role for Intestinal Cell Kinase in Development of Central Nervous, Skeletal, and Endocrine Systems  Journal Articles
• A general mechanism for conditional expression of exaggerated sexually‐selected traits  Journal Articles
• A heteroplasmic mitochondrial complex I gene mutation in adult-onset dystonia  Journal Articles
• A phylogenomic and molecular markers based analysis of the phylum Chlamydiae: proposal to divide the class Chlamydiia into two orders, Chlamydiales and Parachlamydiales ord. nov., and emended description of the class Chlamydiia  Journal Articles
• A phylogenomic reappraisal of family-level divisions within the class Halobacteria: proposal to divide the order Halobacteriales into the families Halobacteriaceae, Haloarculaceae fam. nov., and Halococcaceae fam. nov., and the order Haloferacales into the families, Haloferacaceae and Halorubraceae fam nov.  Journal Articles
• A rifamycin inactivating phosphotransferase family shared by environmental and pathogenic bacteria  Journal Articles
• A spliceosomal intron in Giardia lamblia  Journal Articles
• Accelerated Evolutionary Rate of Housekeeping Genes in Tunicates  Journal Articles
• Activity and subcellular compartmentalization of peroxisome proliferator-activated receptor α are altered by the centrosome-associated protein CAP350  Journal Articles
• Application of the Character Compatibility Approach to Generalized Molecular Sequence Data: Branching Order of the Proteobacterial Subdivisions  Journal Articles
• Asymmetrical Evolution of Cytochrome bd Subunits  Journal Articles
• Ataxin-7 Can Export from the Nucleus via a Conserved Exportin-dependent Signal  Journal Articles
• Caenorhabditis elegans SMA-10/LRIG Is a Conserved Transmembrane Protein that Enhances Bone Morphogenetic Protein Signaling  Journal Articles
• Characterization and Reconstitution of Drosophila γ-Tubulin Ring Complex Subunits  Journal Articles
• Characterization of Kallikrein cDNAs from the African RodentMastomys  Journal Articles
• Characterization of the mouse lysosomal sialidase promoter  Journal Articles
• Chlamydiae-specific proteins and indels: novel tools for studies  Journal Articles
• Citrobacter rodentium virulence in mice associates with bacterial load and the type III effector NleE  Journal Articles
• Cleavage-dependent Ligation by the FLP Recombinase  Journal Articles
• Cloning of the hsp70 (dnaK) genes from Rhizobium meliloti and Pseudomonas cepacia: phylogenetic analyses of mitochondrial origin based on a highly conserved protein sequence  Journal Articles
• Cofilin Nuclear-Cytoplasmic Shuttling Affects Cofilin-Actin Rod Formation During Stress  Journal Articles
• Comparative Genetics of the rdar Morphotype inSalmonella  Journal Articles
• Comparative analysis of non-coding RNAs in the antibiotic-producing Streptomyces bacteria  Journal Articles
• Complete genome sequence of a raccoon rabies virus isolate  Journal Articles
• Conservation of Lotus and Arabidopsis Basic Helix-Loop-Helix Proteins Reveals New Players in Root Hair Development      Journal Articles
• Conserved domains of the class A scavenger receptors: evolution and function  Journal Articles
• Conserved indels in essential proteins that are distinctive characteristics of Chlamydiales and provide novel means for their identification  Journal Articles
• Conserved indels in protein sequences that are characteristic of the phylum Actinobacteria  Journal Articles
• Conserved inserts in the Hsp60 (GroEL) and Hsp70 (DnaK) proteins are essential for cellular growth  Journal Articles
• Conserved signature indels and signature proteins as novel tools for understanding microbial phylogeny and systematics: identification of molecular signatures that are specific for the phytopathogenic genera Dickeya, Pectobacterium and Brenneria  Journal Articles
• Conserved, unstructured regions in Pseudomonas aeruginosa PilO are important for type IVa pilus function  Journal Articles
• Core Histones of the Amitochondriate Protist, Giardia lamblia  Journal Articles
• Cyclin-dependent Kinase 5 (Cdk5) Activation Domain of Neuronal Cdk5 Activator  Journal Articles
• Development of Transcriptomic Resources for Interrogating the Biosynthesis of Monoterpene Indole Alkaloids in Medicinal Plant Species  Journal Articles
• Drosophila ELYS regulates Dorsal dynamics during development  Journal Articles
• Evolution of Allosteric Control in Glycogen Phosphorylase  Journal Articles
• Evolution of High-Branching Deoxyribozymes from a Catalytic DNA with a Three-Way Junction  Journal Articles
• Evolutionary analysis of selective constraints identifies ameloblastin (AMBN) as a potential candidate for amelogenesis imperfecta  Journal Articles
• Evolutionary relationships among photosynthetic prokaryotes (Heliobacterium chlorum, Chloroflexus aurantiacus, cyanobacteria, Chlorobium tepidum and proteobacteria): implications regarding the origin of photosynthesis  Journal Articles
• Folding similarity of the outer pore region in prokaryotic and eukaryotic sodium channels revealed by docking of conotoxins GIIIA, PIIIA, and KIIIA in a NavAb-based model of Nav1.4  Journal Articles
• FuncPatch: a web server for the fast Bayesian inference of conserved functional patches in protein 3D structures  Journal Articles
• Functional role of conserved residues in the characteristic secretion NTPase motifs of the Pseudomonas aeruginosa type IV pilus motor proteins PilB, PilT and PilU  Journal Articles
• Genomic Analyses Identify Novel Molecular Signatures Specific for the Caenorhabditis and other Nematode Taxa Providing Novel Means for Genetic and Biochemical Studies  Journal Articles
• HSP70 phylogeny and the relationship between archaebacteria, eubacteria, and eukaryotes  Journal Articles
• Homology Models of μ-Opioid Receptor with Organic and Inorganic Cations at Conserved Aspartates in the Second and Third Transmembrane Domains  Journal Articles
• Huntingtin contains a highly conserved nuclear export signal  Journal Articles
• Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity  Journal Articles
• Identification of a conserved 8 aa insert in the PIP5K protein in the Saccharomycetaceae family of fungi and the molecular dynamics simulations and structural analysis to investigate its potential functional role  Journal Articles
• Identification of the Regulatory Logic Controlling Salmonella Pathoadaptation by the SsrA-SsrB Two-Component System  Journal Articles
• Identification of the putative goldfish (Carassius auratus) magnesium transporter SLC41a1 and functional regulation in the gill, kidney, and intestine in response to dietary and environmental manipulations  Journal Articles
• Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development  Journal Articles
• In vitro selection of deoxyribozymes with DNA capping activity  Journal Articles
• Increased Substitution Rates Surrounding Low-Complexity Regions within Primate Proteins  Journal Articles
• Intron-specific patterns of divergence of lin-11 regulatory function in the C. elegans nervous system  Journal Articles
• Isolation of a novel gene from the DiGeorge syndrome critical region with homology to Drosophila gdl and to human LAMC1 genes  Journal Articles
• Mechanism of aminoglycoside 3'-phosphotransferase type IIIa: His188 is not a phosphate-accepting residue  Journal Articles
• Molecular Mechanism of the Enterococcal Aminoglycoside 6‘-N-Acetyltransferase‘:  Role of GNAT-Conserved Residues in the Chemistry of Antibiotic Inactivation  Journal Articles
• Molecular mechanism of aminoglycoside antibiotic kinase APH(3')-IIIa: roles of conserved active site residues  Journal Articles
• Molecular signatures (conserved indels) in protein sequences that are specific for the order Pasteurellales and distinguish two of its main clades  Journal Articles
• Molecular signatures (unique proteins and conserved indels) that are specific for the epsilon proteobacteria (Campylobacterales)  Journal Articles
• Molecular signatures for the class Coriobacteriia and its different clades; proposal for division of the class Coriobacteriia into the emended order Coriobacteriales , containing the emended family Coriobacteriaceae and Atopobiaceae fam. nov., and Eggerthellales ord. nov., containing the family Eggerthellaceae fam. nov.  Journal Articles
• Molecular signatures for the phylum Aquificae and its different clades: proposal for division of the phylum Aquificae into the emended order Aquificales, containing the families Aquificaceae and Hydrogenothermaceae, and a new order Desulfurobacteriales ord. nov., containing the family Desulfurobacteriaceae  Journal Articles
• Multiple Occurrences of an Efficient Self-Phosphorylating Deoxyribozyme Motif  Journal Articles
• NLS-dependent nuclear localization of p120ctnis necessary to relieve Kaiso-mediated transcriptional repression  Journal Articles
• Neurological Proteins Are Not Enriched For Repetitive Sequences  Journal Articles
• Novel Molecular Signatures in the PIP4K/PIP5K Family of Proteins Specific for Different Isozymes and Subfamilies Provide Important Insights into the Evolutionary Divergence of this Protein Family  Journal Articles
• Novel Molecular Synapomorphies Demarcate Different Main Groups/Subgroups of Plasmodium and Piroplasmida Species Clarifying Their Evolutionary Relationships  Journal Articles
• Origin and Spread of Photosynthesis Based upon Conserved Sequence Features in Key Bacteriochlorophyll Biosynthesis Proteins  Journal Articles
• OrthoMaM v8: A Database of Orthologous Exons and Coding Sequences for Comparative Genomics in Mammals  Journal Articles
• Periplasmic Domains of Pseudomonas aeruginosa PilN and PilO Form a Stable Heterodimeric Complex  Journal Articles
• Phenotype Presentation for a Novel Mutation Affecting a Conserved Cysteine Residue in Exon 63 of Fibrillin-1 (Cys2633Arg)  Journal Articles
• Phylogenetic analysis and molecular signatures defining a monophyletic clade of heterocystous cyanobacteria and identifying its closest relatives  Journal Articles
• Phylogenetic framework for the phylum Tenericutes based on genome sequence data: proposal for the creation of a new order Mycoplasmoidales ord. nov., containing two new families Mycoplasmoidaceae fam. nov. and Metamycoplasmataceae fam. nov. harbouring Eperythrozoon, Ureaplasma and five novel genera  Journal Articles
• Phylogenomics and molecular signatures for the order Neisseriales: proposal for division of the order Neisseriales into the emended family Neisseriaceae and Chromobacteriaceae fam. nov.  Journal Articles
• Phylogeny and molecular signatures (conserved proteins and indels) that are specific for the Bacteroidetes and Chlorobi species  Journal Articles
• Phylogeny and shared conserved inserts in proteins provide evidence that Verrucomicrobia are the closest known free-living relatives of chlamydiae  Journal Articles
• Plasmodium possesses dynein light chain classes that are unique and conserved across species  Journal Articles
• Polyomavirus large T-antigen binds the ‘pRb related’ protein p130 through sequences in conserved region 2  Journal Articles
• Protein signatures distinctive of chlamydial species: horizontal transfers of cell wall biosynthesis genes glmU from archaea to chlamydiae and murA between chlamydiae and Streptomyces a aThe GenBank accession numbers for the sequences reported in this paper are indicated in the text.  Journal Articles
• Revitalization of Six Abandoned Catalytic DNA Species Reveals a Common Three-way Junction Framework and Diverse Catalytic Cores  Journal Articles
• Robustness encoded across essential and accessory replicons of the ecologically versatile bacterium Sinorhizobium meliloti  Journal Articles
• Role of RpoS in the Virulence of Citrobacter rodentium  Journal Articles
• SUMOylation of periplakin is critical for efficient reorganization of keratin filament network  Journal Articles
• Secondary-Structure Characterization of Two Proficient Kinase Deoxyribozymes  Journal Articles
• Selection and Slippage Creating Serine Homopolymers  Journal Articles
• Signature proteins for the major clades of Cyanobacteria  Journal Articles
• Signature sequences in diverse proteins provide evidence for the late divergence of the Order Aquificales.  Journal Articles
• Six novel mutations in the myophosphorylase gene in patients with McArdle disease and a family with pseudo-dominant inheritance pattern  Journal Articles
• Social insect genomes exhibit dramatic evolution in gene composition and regulation while preserving regulatory features linked to sociality  Journal Articles
• State-dependent inter-repeat contacts of exceptionally conserved asparagines in the inner helices of sodium and calcium channels  Journal Articles
• Structural Insights into the Regulation of Foreign Genes in Salmonella by the Hha/H-NS Complex  Journal Articles
• Structural and Kinetic Characterization of the LPS Biosynthetic Enzyme d-α,β-d-Heptose-1,7-bisphosphate Phosphatase (GmhB) from Escherichia coli,  Journal Articles
• Structural and phylogenetic analysis of a conserved actinobacteria-specific protein (ASP1; SCO1997) from Streptomyces coelicolor  Journal Articles
• Structural basis for alginate secretion across the bacterial outer membrane  Journal Articles
• Structural motif screening reveals a novel, conserved carbohydrate-binding surface in the pathogenesis-related protein PR-5d  Journal Articles
• The C. difficile toxin B membrane translocation machinery is an evolutionarily conserved protein delivery apparatus  Journal Articles
• The COOH terminus of aminoglycoside phosphotransferase (3')-IIIa is critical for antibiotic recognition and resistance  Journal Articles
• The Conserved Tetratricopeptide Repeat-Containing C-Terminal Domain of Pseudomonas aeruginosa FimV Is Required for Its Cyclic AMP-Dependent and -Independent Functions  Journal Articles
• The Functional Role of Conserved Acidic Residues of the Qcr7 Protein of the Cytochrome bc1 Complex in Saccharomyces cerevisiae  Journal Articles
• The Phylogeny and Signature Sequences Characteristics ofFibrobacteres,Chlorobi, andBacteroidetes  Journal Articles
• The Transactivation Function of the Pea3 Subfamily Ets Transcription Factors Is Regulated by Sumoylation  Journal Articles
• The Unc-119 Family of Neural Proteins is Functionally Conserved Between Humans,DrosophilaandC. Elegans  Journal Articles
• The evolution of the class A scavenger receptors  Journal Articles
• The generation of a simian adenoviral vectored HCV vaccine encoding genetically conserved gene segments to target multiple HCV genotypes  Journal Articles
• Three New β-Globin Gene Promoter Mutations Identified Through Newborn Screening  Journal Articles
• Transcriptome data reveal conserved patterns of fruiting body development and response to heat stress in the mushroom-forming fungus Flammulina filiformis  Journal Articles
• Two Conserved Histidine Residues Are Critical to the Function of the TagF-like Family of Enzymes  Journal Articles
• Utilizing novel Escherichia coli‐specific conserved signature proteins for enhanced monitoring of recreational water quality  Journal Articles
• XPF with mutations in its conserved nuclease domain is defective in DNA repair but functions in TRF2-mediated telomere shortening  Journal Articles
• Xenopus fraseri: Mr. Fraser, where did your frog come from?  Journal Articles
• YjeQ, an Essential, Conserved, Uncharacterized Protein from Escherichia coli, Is an Unusual GTPase with Circularly Permuted G-Motifs and Marked Burst Kinetics  Journal Articles