Amyloid beta-Peptides Concept

subject area of

• In vivoimaging of prodromal hippocampus CA1 subfield oxidative stress in models of Alzheimer disease and Angelman syndrome  Journal Articles
• A New Function of Human HtrA2 as an Amyloid-β Oligomerization Inhibitor  Journal Articles
• A solution NMR toolset to probe the molecular mechanisms of amyloid inhibitors  Journal Articles
• Amyloid-targeted therapeutics in Alzheimer's disease: use of human albumin in plasma exchange as a novel approach for Abeta mobilization.  Journal Articles
• Amyloid-β_25–35peptides aggregate into cross-β sheets in unsaturated anionic lipid membranes at high peptide concentrations  Journal Articles
• An aptamer‐based magnetic resonance imaging contrast agent for detecting oligomeric amyloid‐β in the brain of an Alzheimer's disease mouse model  Journal Articles
• Analysis and Optimization of Saturation Transfer Difference NMR Experiments Designed to Map Early Self-Association Events in Amyloidogenic Peptides  Journal Articles
• Antagonistic Effects of β-Site Amyloid Precursor Protein-cleaving Enzymes 1 and 2 on β-Amyloid Peptide Production in Cells  Journal Articles
• Anti-Aβ agents for mild to moderate Alzheimer's disease: systematic review and meta-analysis  Journal Articles
• Anticoagulation in patients with cerebral amyloid angiopathy  Journal Articles
• Association of Plasma Biomarkers With Longitudinal Atrophy and Microvascular Burden on MRI Across Neurodegenerative and Cerebrovascular Diseases.  Journal Articles
• Association of circulating markers with cognitive decline after radiation therapy for brain metastasis  Journal Articles
• Association of plasma biomarkers with cognition, cognitive decline, and daily function across and within neurodegenerative diseases: Results from the Ontario Neurodegenerative Disease Research Initiative  Journal Articles
• Atomic-resolution map of the interactions between an amyloid inhibitor protein and amyloid β (Aβ) peptides in the monomer and protofibril states  Journal Articles
• Aβ Association Inhibition by Transferrin  Journal Articles
• Basic Science and Pathogenesis.  Journal Articles
• Brain-derived neurotrophic factor and TrkB expression in the “oldest-old,” the 90+ Study: correlation with cognitive status and levels of soluble amyloid-beta  Journal Articles
• CREB expression mediates amyloid β-induced basal BDNF downregulation  Journal Articles
• CSF and plasma biomarkers in cerebral amyloid angiopathy: A single-center study and a systematic review/meta-analysis  Journal Articles
• Cholinergic Surveillance over Hippocampal RNA Metabolism and Alzheimer's-Like Pathology  Journal Articles
• Cholinotrophic basal forebrain system alterations in 3xTg-AD transgenic mice  Journal Articles
• Correlation Analysis of Capillary APOE, VEGF and eNOS Expression in Alzheimer Brains  Journal Articles
• Curcumin and Homotaurine Suppress Amyloid-β_25–35 Aggregation in Synthetic Brain Membranes  Journal Articles
• Decreased Brain-Derived Neurotrophic Factor Depends on Amyloid Aggregation State in Transgenic Mouse Models of Alzheimer's Disease  Journal Articles
• Detection of hemorrhagic and axonal pathology in mild traumatic brain injury using advanced MRI: Implications for neurorehabilitation  Journal Articles
• Differential effects of chronic immunosuppression on behavioral, epigenetic, and Alzheimer’s disease-associated markers in 3xTg-AD mice  Journal Articles
• Discovery of Butyrylcholinesterase-Activated Near-Infrared Fluorogenic Probe for Live-Cell and In Vivo Imaging  Journal Articles
• Distinct spatial contributions of amyloid pathology and cerebral small vessel disease to hippocampal morphology  Journal Articles
• Dynamic relationships between age, amyloid-β deposition, and glucose metabolism link to the regional vulnerability to Alzheimer’s disease  Journal Articles
• Efficacy and Safety of Plasma Exchange with 5% Albumin to Modify Cerebrospinal Fluid and Plasma Amyloid-β Concentrations and Cognition Outcomes in Alzheimer's Disease Patients: A Multicenter, Randomized, Controlled Clinical Trial.  Journal Articles
• Entorhinal cortex of aged subjects with Down's syndrome shows severe neuronal loss caused by neurofibrillary pathology  Journal Articles
• Evidence for Altered LRP/RAGE Expression in Alzheimer Lesion Pathogenesis  Journal Articles
• Guanosine Inhibits CD40 Receptor Expression and Function Induced by Cytokines and β Amyloid in Mouse Microglia Cells  Journal Articles
• Guanosine protects SH-SY5Y cells against β-amyloid-induced apoptosis  Journal Articles
• Human Serum Albumin Inhibits Aβ Fibrillization through a “Monomer-Competitor” Mechanism  Journal Articles
• Impact of age, hypercholesterolemia, and the vitamin D receptor on brain endogenous β‐amyloid peptide accumulation in mice  Journal Articles
• In Vitro Amyloid-β Binding and Inhibition of Amyloid-β Self-Association by Therapeutic Albumin  Journal Articles
• Interactions of intrinsically disordered proteins with the unconventional chaperone human serum albumin: From mechanisms of amyloid inhibition to therapeutic opportunities  Journal Articles
• Iron Biochemistry is Correlated with Amyloid Plaque Morphology in an Established Mouse Model of Alzheimer's Disease  Journal Articles
• Large-scale plasma proteomic profiling identifies a high-performance biomarker panel for Alzheimer's disease screening and staging.  Journal Articles
• Mapping the Interactions between the Alzheimer’s Aβ-Peptide and Human Serum Albumin beyond Domain Resolution  Journal Articles
• Mathematical Modeling for the Pathogenesis of Alzheimer's Disease  Journal Articles
• Mechanisms of the Beneficial Effects of Exercise on Brain-Derived Neurotrophic Factor Expression in Alzheimer’s Disease  Journal Articles
• Membrane-Modulating Drugs can Affect the Size of Amyloid-β25–35 Aggregates in Anionic Membranes  Journal Articles
• Microglial cells are the driving force in fibrillar plaque formation, whereas astrocytes are a leading factor in plaque degradation  Journal Articles
• Molecular Mechanism for the (−)-Epigallocatechin Gallate-Induced Toxic to Nontoxic Remodeling of Aβ Oligomers  Journal Articles
• Neurofibrillary Tangles and Senile Plaques in Alzheimers Brains are Associated with Reduced Capillary Expression of Vascular Endothelial Growth Factor and Endothelial Nitric Oxide Synthase  Journal Articles
• Neuronal loss and β-amyloid removal in the amygdala of people with Down syndrome☆  Journal Articles
• Oligomeric Amyloid Decreases Basal Levels of Brain-Derived Neurotrophic factor (BDNF) mRNA via Specific Downregulation of BDNF Transcripts IV and V in Differentiated Human Neuroblastoma Cells  Journal Articles
• Posttranslational Nitro-Glycative Modifications of Albumin in Alzheimer's Disease: Implications in Cytotoxicity and Amyloid-β Peptide Aggregation  Journal Articles
• Preventing Alzheimer’s Disease  Journal Articles
• Probing modifications of the neuronal cytoskeleton  Journal Articles
• Reduced Tissue Levels of Noradrenaline Are Associated with Behavioral Phenotypes of the TgCRND8 Mouse Model of Alzheimer's Disease  Journal Articles
• Reduction in Vascular Endothelial Growth Factor Expression in the Superior Temporal, Hippocampal, and Brainstem Regions in Alzheimer’s Disease  Journal Articles
• Review: Modulating Factors in Amyloid-β Fibril Formation  Journal Articles
• Safety and efficacy of active and passive immunotherapy in mild-to-moderate Alzheimer’s disease: A systematic review and network meta-analysis  Journal Articles
• Sex-Dependent Differences in Spontaneous Autoimmunity in Adult 3xTg-AD Mice  Journal Articles
• Stoichiometry and Affinity of the Human Serum Albumin-Alzheimer's Aβ Peptide Interactions  Journal Articles
• Structural determinants of the interactions of catechins with Aβ oligomers and lipid membranes  Journal Articles
• Synthesis and Screening of a Library of Re/Tc-Based Amyloid Probes Derived from β-Breaker Peptides  Journal Articles
• The Effects of Resveratrol, Caffeine, β‐Carotene, and Epigallocatechin Gallate (EGCG) on Amyloid‐β25--35 Aggregation in Synthetic Brain Membranes  Journal Articles
• The Interaction between Amyloid-β Peptides and Anionic Lipid Membranes Containing Cholesterol and Melatonin  Journal Articles
• The Prion Protein Ligand, Stress-Inducible Phosphoprotein 1, Regulates Amyloid-β Oligomer Toxicity  Journal Articles
• The possible role of capillary cerebral amyloid angiopathy in Alzheimer lesion development: a regional comparison  Journal Articles
• Therapeutic plasma exchange with albumin: a new approach to treat Alzheimer's disease.  Journal Articles
• Total and Mitochondrial Nitrosative Stress, Decreased Brain-Derived Neurotrophic Factor (BDNF) Levels and Glutamate Uptake, and Evidence of Endoplasmic Reticulum Stress in the Hippocampus of Vitamin A-Treated Rats  Journal Articles
• Treatment of Alzheimer disease using combination therapy with plasma exchange and haemapheresis with albumin and intravenous immunoglobulin: Rationale and treatment approach of the AMBAR (Alzheimer Management By Albumin Replacement) study.  Journal Articles
• Trehalose Conjugates of Silybin as Prodrugs for Targeting Toxic Aβ Aggregates  Journal Articles
• Understanding the Molecular Basis for the Inhibition of the Alzheimer's Aβ-Peptide Oligomerization by Human Serum Albumin Using Saturation Transfer Difference and Off-Resonance Relaxation NMR Spectroscopy  Journal Articles
• Use of lecanemab and donanemab in the Canadian healthcare system: Evidence, challenges, and areas for future research.  Journal Articles
• Vascular burden and cognition: Mediating roles of neurodegeneration and amyloid PET  Journal Articles