Amyloid beta-Peptides Concept

subject area of

• In vivoimaging of prodromal hippocampus CA1 subfield oxidative stress in models of Alzheimer disease and Angelman syndrome  Academic Article
• A New Function of Human HtrA2 as an Amyloid-β Oligomerization Inhibitor  Academic Article
• A biophysical toolset to probe the microscopic processes underlying protein aggregation and its inhibition by molecular chaperones  Academic Article
• A solution NMR toolset to probe the molecular mechanisms of amyloid inhibitors  Academic Article
• Amyloid-β_25–35peptides aggregate into cross-β sheets in unsaturated anionic lipid membranes at high peptide concentrations  Academic Article
• An aptamer‐based magnetic resonance imaging contrast agent for detecting oligomeric amyloid‐β in the brain of an Alzheimer's disease mouse model  Academic Article
• Analysis and Optimization of Saturation Transfer Difference NMR Experiments Designed to Map Early Self-Association Events in Amyloidogenic Peptides  Academic Article
• Anti-Aβ agents for mild to moderate Alzheimer's disease: systematic review and meta-analysis  Academic Article
• Association of circulating markers with cognitive decline after radiation therapy for brain metastasis  Academic Article
• Atomic-resolution map of the interactions between an amyloid inhibitor protein and amyloid β (Aβ) peptides in the monomer and protofibril states  Academic Article
• Aβ Association Inhibition by Transferrin  Academic Article
• Brain-derived neurotrophic factor and TrkB expression in the “oldest-old,” the 90+ Study: correlation with cognitive status and levels of soluble amyloid-beta  Academic Article
• CREB expression mediates amyloid β-induced basal BDNF downregulation  Academic Article
• Cholinergic Surveillance over Hippocampal RNA Metabolism and Alzheimer's-Like Pathology  Academic Article
• Cholinotrophic basal forebrain system alterations in 3xTg-AD transgenic mice  Academic Article
• Correlation Analysis of Capillary APOE, VEGF and eNOS Expression in Alzheimer Brains  Academic Article
• Curcumin and Homotaurine Suppress Amyloid-β_25–35 Aggregation in Synthetic Brain Membranes  Academic Article
• Decreased Brain-Derived Neurotrophic Factor Depends on Amyloid Aggregation State in Transgenic Mouse Models of Alzheimer's Disease  Academic Article
• Detection of hemorrhagic and axonal pathology in mild traumatic brain injury using advanced MRI: Implications for neurorehabilitation  Academic Article
• Differential effects of chronic immunosuppression on behavioral, epigenetic, and Alzheimer’s disease-associated markers in 3xTg-AD mice  Academic Article
• Discovery of Butyrylcholinesterase-Activated Near-Infrared Fluorogenic Probe for Live-Cell and In Vivo Imaging  Academic Article
• Dynamic relationships between age, amyloid-β deposition, and glucose metabolism link to the regional vulnerability to Alzheimer’s disease  Academic Article
• Entorhinal cortex of aged subjects with Down's syndrome shows severe neuronal loss caused by neurofibrillary pathology  Academic Article
• Evidence for Altered LRP/RAGE Expression in Alzheimer Lesion Pathogenesis  Academic Article
• Guanosine Inhibits CD40 Receptor Expression and Function Induced by Cytokines and β Amyloid in Mouse Microglia Cells  Academic Article
• Guanosine protects SH-SY5Y cells against β-amyloid-induced apoptosis  Academic Article
• Human Serum Albumin Inhibits Aβ Fibrillization through a “Monomer-Competitor” Mechanism  Academic Article
• Impact of age, hypercholesterolemia, and the vitamin D receptor on brain endogenous β‐amyloid peptide accumulation in mice  Academic Article
• In Vitro Amyloid-β Binding and Inhibition of Amyloid-β Self-Association by Therapeutic Albumin  Academic Article
• Interactions of intrinsically disordered proteins with the unconventional chaperone human serum albumin: From mechanisms of amyloid inhibition to therapeutic opportunities  Academic Article
• Iron Biochemistry is Correlated with Amyloid Plaque Morphology in an Established Mouse Model of Alzheimer's Disease  Academic Article
• Mapping the Interactions between the Alzheimer’s Aβ-Peptide and Human Serum Albumin beyond Domain Resolution  Academic Article
• Mathematical Modeling for the Pathogenesis of Alzheimer's Disease  Academic Article
• Membrane-Modulating Drugs can Affect the Size of Amyloid-β25–35 Aggregates in Anionic Membranes  Academic Article
• Microglial cells are the driving force in fibrillar plaque formation, whereas astrocytes are a leading factor in plaque degradation  Academic Article
• Molecular Mechanism for the (−)-Epigallocatechin Gallate-Induced Toxic to Nontoxic Remodeling of Aβ Oligomers  Academic Article
• Neurofibrillary Tangles and Senile Plaques in Alzheimers Brains are Associated with Reduced Capillary Expression of Vascular Endothelial Growth Factor and Endothelial Nitric Oxide Synthase  Academic Article
• Neuronal loss and β-amyloid removal in the amygdala of people with Down syndrome☆  Academic Article
• Oligomeric Amyloid Decreases Basal Levels of Brain-Derived Neurotrophic factor (BDNF) mRNA via Specific Downregulation of BDNF Transcripts IV and V in Differentiated Human Neuroblastoma Cells  Academic Article
• Preventing Alzheimer’s Disease  Academic Article
• Probing modifications of the neuronal cytoskeleton  Academic Article
• Reduced Tissue Levels of Noradrenaline Are Associated with Behavioral Phenotypes of the TgCRND8 Mouse Model of Alzheimer's Disease  Academic Article
• Reduction in Vascular Endothelial Growth Factor Expression in the Superior Temporal, Hippocampal, and Brainstem Regions in Alzheimer’s Disease  Academic Article
• Review: Modulating Factors in Amyloid-β Fibril Formation  Academic Article
• Safety and efficacy of active and passive immunotherapy in mild-to-moderate Alzheimer’s disease: A systematic review and network meta-analysis  Academic Article
• Sex-Dependent Differences in Spontaneous Autoimmunity in Adult 3xTg-AD Mice  Academic Article
• Stoichiometry and Affinity of the Human Serum Albumin-Alzheimer's Aβ Peptide Interactions  Academic Article
• Structural determinants of the interactions of catechins with Aβ oligomers and lipid membranes  Academic Article
• Synthesis and Screening of a Library of Re/Tc-Based Amyloid Probes Derived from β-Breaker Peptides  Academic Article
• The Effects of Resveratrol, Caffeine, β‐Carotene, and Epigallocatechin Gallate (EGCG) on Amyloid‐β25--35 Aggregation in Synthetic Brain Membranes  Academic Article
• The Interaction between Amyloid-β Peptides and Anionic Lipid Membranes Containing Cholesterol and Melatonin  Academic Article
• The Prion Protein Ligand, Stress-Inducible Phosphoprotein 1, Regulates Amyloid-β Oligomer Toxicity  Academic Article
• The possible role of capillary cerebral amyloid angiopathy in Alzheimer lesion development: a regional comparison  Academic Article
• Total and Mitochondrial Nitrosative Stress, Decreased Brain-Derived Neurotrophic Factor (BDNF) Levels and Glutamate Uptake, and Evidence of Endoplasmic Reticulum Stress in the Hippocampus of Vitamin A-Treated Rats  Academic Article
• Trehalose Conjugates of Silybin as Prodrugs for Targeting Toxic Aβ Aggregates  Academic Article
• Understanding the Molecular Basis for the Inhibition of the Alzheimer's Aβ-Peptide Oligomerization by Human Serum Albumin Using Saturation Transfer Difference and Off-Resonance Relaxation NMR Spectroscopy  Academic Article
• Vascular burden and cognition: Mediating roles of neurodegeneration and amyloid PET  Academic Article