Johnston, Bradley

Affiliations

Faculty of Health Sciences , McMaster University
Associate Professor (Part-Time), Health Research Methods, Evidence, and Impact , Faculty of Health Sciences
Associate Professor (Part-Time), Health Research Methods, Evidence, and Impact , Faculty of Health Sciences

Scholarly Activity in McMaster Experts

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selected scholarly activity

academic article
- Microbial Preparations (Probiotics) for the Prevention of Clostridium difficile Infection in Adults and Children: An Individual Patient Data Meta-analysis of 6,851 Participants.. Infection Control and Hospital Epidemiology. 39:771-781. 2018
- Using decision thresholds for ranking treatments in network meta-analysis results in more informative rankings.. Journal of Clinical Epidemiology. 98:62-69. 2018
- Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children.. Cochrane Database of Systematic Reviews. 12:CD006095. 2017
- Presentation approaches for enhancing interpretability of patient-reported outcomes (PROs) in meta-analysis: a protocol for a systematic survey of Cochrane reviews.. BMJ Open. 7:e017138. 2017
- The Scientific Basis of Guideline Recommendations on Sugar Intake.. Annals of Internal Medicine. 167:219. 2017
- GRADE guidelines 17: assessing the risk of bias associated with missing participant outcome data in a body of evidence.. Journal of Clinical Epidemiology. 87:14-22. 2017
- Premature Discontinuation of Pediatric Randomized Controlled Trials: A Retrospective Cohort Study.. Journal of Pediatrics. 184:209-214.e1. 2017
- Effect of standardized training on the reliability of the Cochrane risk of bias assessment tool: a prospective study.. Systematic Reviews. 6:44. 2017
- Minimally Important Differences in Patient or Proxy-Reported Outcome Studies Relevant to Children: A Systematic Review.. Pediatrics. 139. 2017
- The Scientific Basis of Guideline Recommendations on Sugar Intake: A Systematic Review.. Annals of Internal Medicine. 166:257-267. 2017
- Authors seldom report the most patient-important outcomes and absolute effect measures in systematic review abstracts.. Journal of Clinical Epidemiology. 81:3-12. 2017
- Best (but oft-forgotten) practices: intention-to-treat, treatment adherence, and missing participant outcome data in the nutrition literature.. American Journal of Clinical Nutrition. 104:1197-1201. 2016
- Limited responsiveness related to the minimal important difference of patient-reported outcomes in rare diseases.. Journal of Clinical Epidemiology. 79:10-21. 2016
- Probiotics and the Prevention of Antibiotic-Associated Diarrhea in Infants and Children.. JAMA - Journal of the American Medical Association. 316:1484-1485. 2016
- Influence of unhealthy food and beverage marketing on children's dietary intake and preference: a systematic review and meta-analysis of randomized trials.. Obesity Reviews. 17:945-959. 2016
- CONSORT extension for reporting N-of-1 trials (CENT) 2015 Statement.. Journal of Clinical Epidemiology. 76:9-17. 2016
- CONSORT extension for reporting N-of-1 trials (CENT) 2015: explanation and elaboration.. Journal of Clinical Epidemiology. 76:18-46. 2016
- Prevention of Clostridium difficile Infection: A Systematic Survey of Clinical Practice Guidelines.. Infection Control and Hospital Epidemiology. 37:901-908. 2016
- Diverse criteria and methods are used to compare treatment effect estimates: a scoping review.. Journal of Clinical Epidemiology. 75:29-39. 2016
- Agreements between Industry and Academia on Publication Rights: A Retrospective Study of Protocols and Publications of Randomized Clinical Trials.. PLoS Medicine. 13:e1002046. 2016
- Systematic reviews experience major limitations in reporting absolute effects.. Journal of Clinical Epidemiology. 72:16-26. 2016
- Probiotics and synbiotics for the prevention of postoperative infections following abdominal surgery: a systematic review and meta-analysis of randomized controlled trials.. Journal of Hospital Infection. 92:130-139. 2016
- Do clinicians understand the size of treatment effects? A randomized survey across 8 countries.. CMAJ. 188:25-32. 2016
- An analysis of protocols and publications suggested that most discontinuations of clinical trials were not based on preplanned interim analyses or stopping rules.. Journal of Clinical Epidemiology. 69:152-160. 2016
- PATIENT-REPORTED OUTCOMES IN RARE LYSOSOMAL STORAGE DISEASES: KEY INFORMANT INTERVIEWS AND A SYSTEMATIC REVIEW PROTOCOL.. International Journal of Technology Assessment in Health Care. 32:393-399. 2016
- Planning and reporting of quality-of-life outcomes in cancer trials.. Annals of Oncology. 27:209. 2016
- Premature Discontinuation of Randomized Trials in Critical and Emergency Care: A Retrospective Cohort Study.. Critical Care Medicine. 44:130-137. 2016
- Reporting missing participant data in randomised trials: systematic survey of the methodological literature and a proposed guide.. BMJ Open. 5:e008431. 2015
- Minimally important difference estimates and methods: a protocol.. BMJ Open. 5:e007953. 2015
- Optimal Strategies for Reporting Pain in Clinical Trials and Systematic Reviews: Recommendations from an OMERACT 12 Workshop.. Journal of Rheumatology. 42:1962-1970. 2015
- Reporting, handling and assessing the risk of bias associated with missing participant data in systematic reviews: a methodological survey.. BMJ Open. 5:e009368. 2015
- Planning and reporting of quality-of-life outcomes in cancer trials.. Annals of Oncology. 26:1966-1973. 2015
- Reporting of IMMPACT-recommended core outcome domains among trials assessing opioids for chronic non-cancer pain.. Pain. 156:1615-1619. 2015
- Although not consistently superior, the absolute approach to framing the minimally important difference has advantages over the relative approach.. Journal of Clinical Epidemiology. 68:888-894. 2015
- Handling trial participants with missing outcome data when conducting a meta-analysis: a systematic survey of proposed approaches.. Systematic Reviews. 4:98. 2015
- Completion and Publication Rates of Randomized Controlled Trials in Surgery: An Empirical Study.. Annals of Surgery. 262:68-73. 2015
- CONSORT extension for reporting N-of-1 trials (CENT) 2015: Explanation and elaboration.. British Medical Journal BMJ (Clinical research ed.). 350:h1793. 2015
- GRADE guidelines: 13. Preparing Summary of Findings tables and evidence profiles-continuous outcomes (vol 66, pg 173, 2013). Journal of Clinical Epidemiology. 68:475-475. 2015
- Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database of Systematic Reviews. 2015
- Comparison of weight loss among named diet programs in overweight and obese adults: a meta-analysis.. JAMA - Journal of the American Medical Association. 312:923-933. 2014
- Recent advances in patient and proxy-reported quality of life research.. Health and Quality of Life Outcomes. 12:110. 2014
- Subgroup analyses in randomised controlled trials: cohort study on trial protocols and journal publications.. British Medical Journal BMJ (Clinical research ed.). 349:g4539. 2014
- Addressing continuous data measured with different instruments for participants excluded from trial analysis: a guide for systematic reviewers.. Journal of Clinical Epidemiology. 67:560-570. 2014
- Prevalence, characteristics, and publication of discontinued randomized trials.. JAMA - Journal of the American Medical Association. 311:1045-1051. 2014
- Subgroup analyses in randomised controlled trials: cohort study on trial protocols and journal publications.. British Medical Journal BMJ (Clinical research ed.). 349. 2014
- The Quick Mild Cognitive Impairment screen correlated with the Standardized Alzheimer's Disease Assessment Scale-cognitive section in clinical trials.. Journal of Clinical Epidemiology. 67:87-92. 2014
- Patient-reported outcomes in meta-analyses-part 2: methods for improving interpretability for decision-makers.. Health and Quality of Life Outcomes. 11:211. 2013
- A methodological survey of the analysis, reporting and interpretation of Absolute Risk ReductiOn in systematic revieWs (ARROW): a study protocol.. Systematic Reviews. 2:113. 2013
- Addressing continuous data for participants excluded from trial analysis: a guide for systematic reviewers.. Journal of Clinical Epidemiology. 66:1014-1021.e1. 2013
- Combining follow-up and change data is valid in meta-analyses of continuous outcomes: a meta-epidemiological study. Journal of Clinical Epidemiology. 66:847-855. 2013
- Patient-reported outcomes in meta-analyses--Part 1: assessing risk of bias and combining outcomes.. Health and Quality of Life Outcomes. 11:109. 2013
- Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children.. Cochrane Database of Systematic Reviews. CD006095. 2013
- Probiotics for the Prevention of Clostridium difficile-Associated Diarrhea RESPONSE. Annals of Internal Medicine. 158:706-707. 2013
- Conceptual framework for health-related quality of life assessment in acute gastroenteritis.. Journal of Pediatric Gastroenterology and Nutrition. 56:280-289. 2013
- Randomized trials published in higher vs. lower impact journals differ in design, conduct, and analysis.. Journal of Clinical Epidemiology. 66:286-295. 2013
- GRADE guidelines: 13. Preparing summary of findings tables and evidence profiles-continuous outcomes.. Journal of Clinical Epidemiology. 66:173-183. 2013
- Addressing dichotomous data for participants excluded from trial analysis: a guide for systematic reviewers.. PLoS ONE. 8:e57132. 2013
- Probiotics for the prevention of Clostridium difficile-associated diarrhea: a systematic review and meta-analysis.. Annals of Internal Medicine. 157:878-888. 2012
- Methods to convert continuous outcomes into odds ratios of treatment response and numbers needed to treat: meta-epidemiological study. International Journal of Epidemiology. 41:1445-1459. 2012
- Learning from failure--rationale and design for a study about discontinuation of randomized trials (DISCO study).. BMC Medical Research Methodology. 12:131. 2012
- New methods can extend the use of minimal important difference units in meta-analyses of continuous outcome measures.. Journal of Clinical Epidemiology. 65:817-826. 2012
- Formatting modifications in GRADE evidence profiles improved guideline panelists comprehension and accessibility to information. A randomized trial.. Journal of Clinical Epidemiology. 65:748-755. 2012
- Standard 5: Selection, Measurement, and Reporting of Outcomes in Clinical Trials in Children. Pediatrics. 129:S146-S152. 2012
- Potential impact on estimated treatment effects of information lost to follow-up in randomised controlled trials (LOST-IT): systematic review.. British Medical Journal BMJ (Clinical research ed.). 344:e2809. 2012
- Credibility of claims of subgroup effects in randomised controlled trials: systematic review.. British Medical Journal BMJ (Clinical research ed.). 344:e1553. 2012
- Specific instructions for estimating unclearly reported blinding status in randomized trials were reliable and valid.. Journal of Clinical Epidemiology. 65:262-267. 2012
- Evolution of heterogeneity (I2) estimates and their 95% confidence intervals in large meta-analyses.. PLoS ONE. 7:e39471. 2012
- Probiotics for the prevention of pediatric antibiotic-associated diarrhea.. Cochrane Database of Systematic Reviews. CD004827. 2011
- Pooling health-related quality of life outcomes in meta-analysis-a tutorial and review of methods for enhancing interpretability.. Research Synthesis Methods. 2:188-203. 2011
- The influence of study characteristics on reporting of subgroup analyses in randomised controlled trials: systematic review.. British Medical Journal BMJ (Clinical research ed.). 342:d1569. 2011
- Improving the interpretation of quality of life evidence in meta-analyses: the application of minimal important difference units.. Health and Quality of Life Outcomes. 8:116. 2010
- Water and sanitation infrastructure for health: The impact of foreign aid.. Globalization and Health. 6:12. 2010
- Measurement issues in trials of pediatric acute diarrheal diseases: a systematic review.. Pediatrics. 126:e222-e231. 2010
- Subgroup Analysis of Trials Is Rarely Easy (SATIRE): a study protocol for a systematic review to characterize the analysis, reporting, and claim of subgroup effects in randomized trials.. Current Controlled Trials in Cardiovascular Medicine Trials. 10:101. 2009
- Meta-analyses of safety data: a comparison of exact versus asymptotic methods. Statistical Methods in Medical Research. 18:421-432. 2009
- LOST to follow-up Information in Trials (LOST-IT): a protocol on the potential impact.. Current Controlled Trials in Cardiovascular Medicine Trials. 10:40. 2009
- Safety and tolerability of North American ginseng extract in the treatment of pediatric upper respiratory tract infection: a phase II randomized, controlled trial of 2 dosing schedules.. Pediatrics. 122:e402-e410. 2008
- The use of expertise-based randomized controlled trials to assess spinal manipulation and acupuncture for low back pain: a systematic review.. Spine. 33:914-918. 2008
- Surgical versus nonsurgical treatment for back pain. New England Journal of Medicine. 357:1255-1255. 2007
- Adverse events associated with pediatric spinal manipulation: A systematic review.(vol 119, pg e275, 2007). Pediatrics. 120:251-251. 2007
- Adverse events in the manipulation of pediatric patients: Flaws in a systematic review - Reply. Pediatrics. 119:1266-1267. 2007
- Adverse events associated with pediatric spinal manipulation: A systematic review. (vol 119, pg 275, 2007). Pediatrics. 119:867-867. 2007
- Adverse events associated with pediatric spinal manipulation: a systematic review.. Pediatrics. 119:e275-e283. 2007
- Probiotics for pediatric antibiotic-associated diarrhea: a meta-analysis of randomized placebo-controlled trials (vol 175, pg 377, 2006). CMAJ. 175:777-777. 2006
- Investigator-initiated trials are more impartial. Nature Nature: New biology. 443:144-144. 2006
- Probiotics for pediatric antibiotic-associated diarrhea: a meta-analysis of randomized placebo-controlled trials.. CMAJ. 175:377-383. 2006
- Natural health product-drug interactions: a systematic review of clinical trials.. Therapeutic Drug Monitoring. 27:549-557. 2005
- Herb-drug interaction implications ifs pediatric practice: An overview of pharmacokinetic trials. Archives of Pediatrics and Adolescent Medicine. 159:692-692. 2005
- Does Lactobacillus GG prevent antibiotic-associated diarrhea in children?: Part A: Evidence-based answer and summary.. Paediatrics and Child Health. 10:169-171. 2005
- Does Lactobacillus GG prevent antibiotic-associated diarrhea in children?: Part B: Clinical commentary.. Paediatrics and Child Health. 10:170-171. 2005
- Treating C-difficile. CMAJ. 172:447-448. 2005
- n-of-1 randomized controlled trials: an opportunity for complementary and alternative medicine evaluation.. Journal of Alternative and Complementary Medicine. 10:979-984. 2004
conference paper
- Dipeptidyl Peptidase-4 Inhibitors May Reduce the Risk of Major Adverse Cardiovascular Events and All-cause Mortality In Patients With Type 2 Diabetes: Meta-analyses Oof Randomized Controlled Trials. Circulation. 2012