Journal article
Opioids for Chronic Noncancer Pain: A Systematic Review and Meta-analysis
Abstract
Importance: Harms and benefits of opioids for chronic noncancer pain remain unclear. Objective: To systematically review randomized clinical trials (RCTs) of opioids for chronic noncancer pain. Data Sources and Study Selection: The databases of CENTRAL, CINAHL, EMBASE, MEDLINE, AMED, and PsycINFO were searched from inception to April 2018 for RCTs of opioids for chronic noncancer pain vs any nonopioid control. Data Extraction and Synthesis: …
Authors
Busse JW; Wang L; Kamaleldin M; Craigie S; Riva JJ; Montoya L; Mulla SM; Lopes LC; Vogel N; Chen E
Journal
JAMA, Vol. 320, , pp. 2448–2460
Publication Date
2018
DOI
10.1001/jama.2018.18472
ISSN
1538-3598