subject area of
- In vivoimaging of prodromal hippocampus CA1 subfield oxidative stress in models of Alzheimer disease and Angelman syndrome Academic Article
- A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation Academic Article
- Absence of caspase-3 protects against denervation-induced skeletal muscle atrophy Academic Article
- Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis Academic Article
- Adenovirus Evasion of Interferon-Mediated Innate Immunity by Direct Antagonism of a Cellular Histone Posttranslational Modification Academic Article
- An allosteric inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase Academic Article
- Analysis of Anti-Interferon Properties of the Herpes Simplex Virus Type I ICP0 Protein Academic Article
- BRCA2 Mutation-associated Breast Cancers Exhibit a Distinguishing Phenotype Based on Morphology and Molecular Profiles From Tissue Microarrays Academic Article
- CHIP Deficiency Decreases Longevity, with Accelerated Aging Phenotypes Accompanied by Altered Protein Quality Control Academic Article
- Cell Fusion-Induced Activation of Interferon-Stimulated Genes Is Not Required for Restriction of a Herpes Simplex Virus VP16/ICP0 Mutant in Heterokarya Formed between Permissive and Restrictive Cells Academic Article
- Cloning of a Chinese hamster protein homologous to the mouse t-complex protein TCP-1: Structural similarity to the ubiquitous ‘chaperonin’ family of heat-shock proteins Academic Article
-
Cockayne syndrome group B protein regulates
DNA double‐strand break repair and checkpoint activation Academic Article - Disease Variant Landscape of a Large Multiethnic Population of Moyamoya Patients by Exome Sequencing Academic Article
- Disruption of the ASTN2/TRIM32 locus at 9q33.1 is a risk factor in males for autism spectrum disorders, ADHD and other neurodevelopmental phenotypes Academic Article
- E6AP promotes prostate cancer by reducing p27 expression Academic Article
- Evolution of the chaperonin families (HSP60, HSP 10 and TCP-1) of proteins and the origin of eukaryotic cells Academic Article
- Genetic interactions between error-prone and error-free postreplication repair pathways in Saccharomyces cerevisiae Academic Article
- Herpes Simplex Virus ICP0 Mutants Are Hypersensitive to Interferon Academic Article
- Herpes Simplex Virus ICP0 and ICP34.5 Counteract Distinct Interferon-Induced Barriers to Virus Replication Academic Article
- ICP0 Prevents RNase L-Independent rRNA Cleavage in Herpes Simplex Virus Type 1-Infected Cells Academic Article
- Low dose formoterol administration improves muscle function in dystrophic mdx mice without increasing fatigue Academic Article
- Mechanisms Employed by Herpes Simplex Virus 1 to Inhibit the Interferon Response Academic Article
- Moyamoya Disease Susceptibility Variant RNF213 p.R4810K Increases the Risk of Ischemic Stroke Attributable to Large-Artery Atherosclerosis Academic Article
- Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15 Academic Article
- Multilocus loss of DNA methylation in individuals with mutations in the histone H3 Lysine 4 Demethylase KDM5C Academic Article
- NleG Type 3 Effectors from Enterohaemorrhagic Escherichia coli Are U-Box E3 Ubiquitin Ligases Academic Article
- Novel Roles of Cytoplasmic ICP0: Proteasome-Independent Functions of the RING Finger Are Required To Block Interferon-Stimulated Gene Production but Not To Promote Viral Replication Academic Article
- PDLIM7 is a novel target of the ubiquitin ligase Nedd4-1 in skeletal muscle Academic Article
- PML has a predictive role in tumor cell permissiveness to interferon-sensitive oncolytic viruses Academic Article
- Primary structure-based function characterization of BRCT domain replicates in BRCA1 Academic Article
- Rare Copy Number Variation Discovery and Cross-Disorder Comparisons Identify Risk Genes for ADHD Academic Article
- Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT Domain Academic Article
- SIPL1-facilitated PTEN ubiquitination contributes to its association with PTEN Academic Article
- Sequence and structural homology between a mouse T-complex protein TCP-1 and the 'chaperonin' family of bacterial (GroEL, 60-65 kDa heat shock antigen) and eukaryotic proteins. Academic Article
- Smad7 Binds to Smurf2 to Form an E3 Ubiquitin Ligase that Targets the TGFβ Receptor for Degradation Academic Article
- Statistics Commentary Series Academic Article
- TGF-β induces assembly of a Smad2–Smurf2 ubiquitin ligase complex that targets SnoN for degradation Academic Article
- TRIM26 Facilitates HSV-2 Infection by Downregulating Antiviral Responses through the IRF3 Pathway Academic Article
- The Cancer-associated K351N Mutation Affects the Ubiquitination and the Translocation to Mitochondria of p53 Protein Academic Article
- The E3 ubiquitin ligase Mule acts through the ATM–p53 axis to maintain B lymphocyte homeostasis Academic Article
- The Herpes Simplex Virus ICP0 RING Finger Domain Inhibits IRF3- and IRF7-Mediated Activation of Interferon-Stimulated Genes Academic Article
- The RING‐finger scaffold protein Plenty of SH3s targets TAK1 to control immunity signalling inDrosophila Academic Article
- The Ubiquitin Ligase Nedd4-1 Participates in Denervation-Induced Skeletal Muscle Atrophy in Mice Academic Article
- The Ubiquitin–Proteasome System and Cardiovascular Disease Academic Article
- The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4 Academic Article
- The responsiveness of human papillomavirus upstream regulatory regions to herpes simplex virus immediate early proteins Academic Article
- The role of ICP0-Null HSV-1 and interferon signaling defects in the effective treatment of breast adenocarcinoma Academic Article
- The small heat-shock protein α B-crystallin is essential for the nuclear localization of Smad4: impact on pulmonary fibrosis Academic Article
- Truncation of the C-Terminal Acidic Transcriptional Activation Domain of Herpes Simplex Virus VP16 Renders Expression of the Immediate-Early Genes Almost Entirely Dependent on ICP0 Academic Article