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The responsiveness of human papillomavirus...
Journal article

The responsiveness of human papillomavirus upstream regulatory regions to herpes simplex virus immediate early proteins

Abstract

We have tested the responsiveness of the upstream regulatory regions (URR) of human papillomaviruses (HPV) to transactivation by the herpes simplex virus type 1 (HSV-1) immediate early proteins ICP4 (Vmw175) and ICP0 (Vmw110), using recombinant plasmids which contain URRs of HPV 1, 11 or 16 upstream of an SV40-promoted CAT gene. Transfection of the HPV-CAT plasmids into mouse cells expressing a temperature-sensitive ICP4 protein enabled us to …

Authors

McCusker CT; Bacchetti S

Journal

Virus Research, Vol. 11, No. 3, pp. 199–207

Publisher

Elsevier

Publication Date

October 1988

DOI

10.1016/0168-1702(88)90083-4

ISSN

0168-1702