Sulfonamides Concept

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• A Canadian Critical Care Trials Group project in collaboration with the international forum for acute care trialists - Collaborative H1N1 Adjuvant Treatment pilot trial (CHAT): study protocol and design of a randomized controlled trial  Journal Articles
• A Euglena mutant resistant to n-methyl-n-nitroso-p- toluenesulfonamide.  Journal Articles
• AEG3482 Is an Antiapoptotic Compound that Inhibits Jun Kinase Activity and Cell Death through Induced Expression of Heat Shock Protein 70  Journal Articles
• AGA Clinical Practice Update on Integrating Potassium-Competitive Acid Blockers Into Clinical Practice: Expert Review.  Journal Articles
• Activity of venetoclax in patients with relapsed or refractory chronic lymphocytic leukaemia: analysis of the VENICE-1 multicentre, open-label, single-arm, phase 3b trial  Journal Articles
• Acute pain after total hip arthroplasty does not predict the development of chronic postsurgical pain 6 months later  Journal Articles
• American Society of Hematology 2018 guidelines for management of venous thromboembolism: heparin-induced thrombocytopenia  Journal Articles
• An integrative, in situ approach to examining K⁺ flux in resting skeletal muscle  Journal Articles
• An integrative, in situ approach to examining K⁺ flux in resting skeletal muscle  Journal Articles
• An orally active non-selective endothelin receptor antagonist, bosentan, markedly reduces injury in a rat model of colitis  Journal Articles
• Anti-Aβ agents for mild to moderate Alzheimer's disease: systematic review and meta-analysis  Journal Articles
• Anti‐ulcerogenic properties of endothelin receptor antagonists in the rat  Journal Articles
• Argatroban Anticoagulant Therapy in Patients With Heparin-Induced Thrombocytopenia  Journal Articles
• Argatroban Anticoagulation in Patients With Heparin-Induced Thrombocytopenia  Journal Articles
• Argatroban anticoagulation in patients with a history of heparin-induced thrombocytopenia  Journal Articles
• Argatroban as a Heparin Substitute in Cases of Heparin-Induced Thrombocytopenia  Journal Articles
• Association Between Tamsulosin and Serious Ophthalmic Adverse Events in Older Men Following Cataract Surgery  Journal Articles
• Association of Bicuspid Aortic Valve Morphology and Aortic Root Dimensions: A Substudy of the Aortic Stenosis Progression Observation Measuring Effects of Rosuvastatin (ASTRONOMER) Study  Journal Articles
• Atovaquone Suspension Compared with Aerosolized Pentamidine for Prevention ofPneumocystis cariniiPneumonia in Human Immunodeficiency Virus–Infected Subjects Intolerant of Trimethoprim or Sulfonamides  Journal Articles
• Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia  Journal Articles
• Azacitidine and venetoclax for the treatment of accelerated and blast phase myeloproliferative neoplasms and chronic myelomonocytic leukemia: a case series  Journal Articles
• Brought in by force: AMPK, TBC1D1, and contraction-stimulated glucose transport in skeletal muscle  Journal Articles
• Celecoxib as an adjunct in the treatment of depressive or mixed episodes of bipolar disorder: a double‐blind, randomized, placebo‐controlled study  Journal Articles
• Chromanol 293B Binding in KCNQ1 (Kv7.1) Channels Involves Electrostatic Interactions with a Potassium Ion in the Selectivity Filter  Journal Articles
• Chronic opioids regulate K_ATP channel subunit Kir6.2 and carbonic anhydrase I and II expression in rat adrenal chromaffin cells via HIF-2α and protein kinase A  Journal Articles
• Circulating Levels of Matrix Gla Protein and Progression of Aortic Stenosis: A Substudy of the Aortic Stenosis Progression Observation: Measuring Effects of Rosuvastatin (ASTRONOMER) Trial  Journal Articles
• Clinical Trial: Dose-Finding Study of Linaprazan Glurate, A Novel Potassium-Competitive Acid Blocker, Versus Lansoprazole for the Treatment of Erosive Oesophagitis.  Journal Articles
• Clinical Usefulness of Tissue Doppler Imaging in Patients with Mild to Moderate Aortic Stenosis: A Substudy of the Aortic Stenosis Progression Observation Measuring Effects of Rosuvastatin Study  Journal Articles
• Comment: Treatment of Heparin-Induced Thrombocytopenia  Journal Articles
• Comparing binary efficacy outcomes for systemic immunomodulatory treatments for atopic dermatitis in a living systematic review and network meta-analysis  Journal Articles
• Comparison of argatroban and fondaparinux for the management of patients with isolated heparin-induced thrombocytopenia  Journal Articles
• Comprehensive evaluation of adsorption performances of carbonaceous materials for sulfonamide antibiotics removal  Journal Articles
• Converging purinergic and immune signaling pathways drive IL-6 secretion by Fragile X cortical astrocytes via STAT3  Journal Articles
• Crosstalk between the Unfolded Protein Response and NF-κB-Mediated Inflammation in the Progression of Chronic Kidney Disease  Journal Articles
• Current agents for the treatment of patients with heparin-induced thrombocytopenia  Journal Articles
• Cyclic 3’,5’-Adenosine Monophosphate Mediates Dopamine D1-Stimulated Growth Hormone Release from Goldfish Pituitary Cells  Journal Articles
• Dabigatran and Argatroban Diametrically Modulate Thrombin Exosite Function  Journal Articles
• Daily Inhaled Corticosteroid Treatment Should Not Be Prescribed for Mild Persistent Asthma  Journal Articles
• Design and baseline data of a pediatric study with rosuvastatin in familial hypercholesterolemia  Journal Articles
• Differences in the Mechanisms of Proapoptotic BH3 Proteins Binding to Bcl-XL and Bcl-2 Quantified in Live MCF-7 Cells  Journal Articles
• Differences in the clinically effective molar concentrations of four direct thrombin inhibitors explain their variable prothrombin time prolongation  Journal Articles
• Direct Thrombin Inhibitors in Cardiac Disease  Journal Articles
• Direct thrombin inhibitors in acute coronary syndromes: principal results of a meta-analysis based on individual patients' data  Journal Articles
• Does Celecoxib Potentiate the Anticoagulant Effect of Warfarin? A Randomized, Double-Blind, Controlled Trial  Journal Articles
• Drug-Drug Interaction in a Kidney Transplant Recipient Receiving HIV Salvage Therapy and Tacrolimus  Journal Articles
• Drugs targeting Bcl-2 family members as an emerging strategy in cancer  Journal Articles
• Early high-dose rosuvastatin prevented contrast-induced acute kidney injury in non–ST-elevation ACS  Journal Articles
• Early tumor shrinkage is independently associated with improved overall survival among patients with metastatic renal cell carcinoma: a validation study using the COMPARZ cohort  Journal Articles
• Editorial: On‐demand vonoprazan forNERD– when should it be ‘demanded’? Authors' reply  Journal Articles
• Editorial: towards extended acid suppression - the search continues  Journal Articles
• Effect of Evolocumab or Ezetimibe Added to Moderate- or High-Intensity Statin Therapy on LDL-C Lowering in Patients With Hypercholesterolemia  Journal Articles
• Effect of Lipid Lowering With Rosuvastatin on Progression of Aortic Stenosis  Journal Articles
• Effect of rosuvastatin on C-reactive protein and progression of aortic stenosis  Journal Articles
• Effectiveness of Dorzolamide–Timolol (COSOPT) in Patients Who Were Treatment Naive for Open-Angle Glaucoma or Ocular Hypertension: The COSOPT First-Line Study  Journal Articles
• Efficacy and Tolerability of Gefapixant for Treatment of Refractory or Unexplained Chronic Cough  Journal Articles
• Efficacy and safety of a CXCR2 antagonist, AZD5069, in patients with uncontrolled persistent asthma: a randomised, double-blind, placebo-controlled trial  Journal Articles
• Efficacy of 8 Weeks of Sofosbuvir, Velpatasvir, and Voxilaprevir in Patients With Chronic HCV Infection: 2 Phase 3 Randomized Trials  Journal Articles
• Efficacy of Secretagogues in Patients With Irritable Bowel Syndrome With Constipation: Systematic Review and Network Meta-analysis  Journal Articles
• Endothelin receptor antagonist therapy in congenital heart disease with shunt-associated pulmonary arterial hypertension: A qualitative systematic review  Journal Articles
• Endothelin-1 antagonism and nitric oxide augmentation prevents cyclosporine-induced vasomotor impairment  Journal Articles
• Epigenetic regulation of noncanonical menin targets modulates menin inhibitor response in acute myeloid leukemia.  Journal Articles
• Evaluating the effectiveness of rosuvastatin in preventing the progression of diastolic dysfunction in aortic stenosis: A substudy of the aortic stenosis progression observation measuring effects of rosuvastatin (ASTRONOMER) study  Journal Articles
• Everolimus and pazopanib (E/P) benefit genomically selected patients with metastatic urothelial carcinoma  Journal Articles
• Expression of functional cysteinyl leukotriene receptors by human basophils  Journal Articles
• Fondaparinux versus direct thrombin inhibitor therapy for the management of heparin-induced thrombocytopenia (HIT) – Bridging the River Coumarin  Journal Articles
• Gabapentin Decreases Morphine Consumption and Improves Functional Recovery following Total Knee Arthroplasty  Journal Articles
• Gefapixant for Chronic Cough—Reply  Journal Articles
• Genetic Background of Antimicrobial Resistance in Multiantimicrobial-Resistant Escherichia coli Isolates from Feces of Healthy Broiler Chickens in Tunisia  Journal Articles
• Heparin-Induced Thrombocytopenia  Journal Articles
• Heparin-Induced Thrombocytopenia  Journal Articles
• Heparin-induced thrombocytopenia in intensive care patients  Journal Articles
• Heparin-induced thrombocytopenia in the critical care setting: Diagnosis and management^  Journal Articles
• High-content screening identifies kinase inhibitors that overcome venetoclax resistance in activated CLL cells  Journal Articles
• High‐dose intravenous immunoglobulin to treat spontaneous heparin‐induced thrombocytopenia syndrome  Journal Articles
• Hormone-sensitive lipase activity and triacylglycerol hydrolysis are decreased in rat soleus muscle by cyclopiazonic acid  Journal Articles
• Identification and Characterization of AES-135, a Hydroxamic Acid-Based HDAC Inhibitor That Prolongs Survival in an Orthotopic Mouse Model of Pancreatic Cancer  Journal Articles
• Improvements in Objective and Subjective Measures of Chronic Cough with Gefapixant: A Pooled Phase 3 Efficacy Analysis of Predefined Subgroups  Journal Articles
• In adults hospitalized with COVID-19, adding baricitinib vs. dexamethasone to remdesivir did not differ for MV-free survival  Journal Articles
• In high-risk patients with arthritis and previous upper GI bleeding, celecoxib vs naproxen reduced recurrent bleeding  Journal Articles
• Inactivation of biologically active N-methyl-N-nitroso compounds in aqueous solution: effect of various conditions of pH and illumination.  Journal Articles
• Influence of zafirlukast and loratadine on exercise-induced bronchoconstriction  Journal Articles
• Inhibition of Euglena macromolecule synthesis by N-methyl-N-nitro-N-nitrosoguanidine and N-methyl-N-nitroso-p-toluenesulfonamide.  Journal Articles
• Inhibition of carbonic anhydrase IX (CA9) sensitizes renal cell carcinoma to ionizing radiation  Journal Articles
• Insulin Resistance and LVH Progression in Patients With Calcific Aortic Stenosis  Journal Articles
• Interactions of pro-apoptotic BH3 proteins with anti-apoptotic Bcl-2 family proteins measured in live MCF-7 cells using FLIM FRET  Journal Articles
• International Geographic Variation in Event Rates in Trials of Heart Failure With Preserved and Reduced Ejection Fraction  Journal Articles
• Leukotriene D4-induced increases in cytosolic calcium in THP-1 cells: dependence on extracellular calcium and inhibition with selective leukotriene D4 receptor antagonists.  Journal Articles
• Lipid lowering for primary prevention  Journal Articles
• Long‐term follow‐up of VIALE‐A: Venetoclax and azacitidine in chemotherapy‐ineligible untreated acute myeloid leukemia  Journal Articles
• Macitentan reduces progression of TGF-β1-induced pulmonary fibrosis and pulmonary hypertension  Journal Articles
• Management of heparin-induced thrombocytopenia: a critical comparison of lepirudin and argatroban  Journal Articles
• Mechanism of Action of an EPAC1-Selective Competitive Partial Agonist  Journal Articles
• Modified SST–USST for tamsulosin-associated intraocular floppy-iris syndrome  Journal Articles
• Oral appliance with nimesulide is probably more effective than oral appliance alone or with dry needling for reducing orofacial pain in the short term  Journal Articles
• Parenteral Anticoagulants  Journal Articles
• Parenteral Anticoagulants  Journal Articles
• Pharmacologic treatment of GERD: Where we are now, and where are we going?  Books
• Pharmacological actions of a new β‐adrenoceptor agonist, MJ‐9184–1, in anaesthetized cats  Journal Articles
• Pharmacological approaches in celiac disease  Journal Articles
• Phase I/II Study of Pemetrexed With or Without ABT-751 in Advanced or Metastatic Non–Small-Cell Lung Cancer  Journal Articles
• Phase II trial of the histone deacetylase inhibitor belinostat in women with platinum resistant epithelial ovarian cancer and micropapillary (LMP) ovarian tumours  Journal Articles
• Potassium-competitive Acid Blockers: Current Clinical Use and Future Developments  Journal Articles
• Practical considerations for the use of nonsteroidal anti-inflammatory drugs and cyclo-oxygenase-2 inhibitors in hypertension and kidney disease.  Journal Articles
• Prescription of Antibacterial Drugs for HIV-Exposed, Uninfected Infants, Malawi, 2004–2010  Journal Articles
• Progressive, Fatal Thrombosis Associated With Heparin-Induced Thrombocytopenia After Cardiac Surgery Despite “Therapeutic” Anticoagulation With Argatroban: Potential Role for PTT and ACT Confounding  Journal Articles
• Proton Pump Inhibitors Exacerbate NSAID-Induced Small Intestinal Injury by Inducing Dysbiosis  Journal Articles
• Randomised clinical trial: Efficacy and safety of on‐demand vonoprazan versus placebo for non‐erosive reflux disease  Journal Articles
• Rationale, design, and baseline characteristics of a randomized trial to assess the effect of cholesterol lowering on the progression of aortic stenosis  Journal Articles
• Reaction of and with DNA in vitro  Journal Articles
• Regulation of kynurenine biosynthesis during influenza virus infection  Journal Articles
• Regulation of plasminogen activator inhibitor‐1 secretion by urokinase and tissue plasminogen activator in rat epithelioid‐type smooth muscle cells  Journal Articles
• Relaxin alters cardiac myofilament function through a PKC-dependent pathway  Journal Articles
• Risk of adverse events among older adults following co-prescription of clarithromycin and statins not metabolized by cytochrome P450 3A4  Journal Articles
• SERAPHIN haemodynamic substudy: the effect of the dual endothelin receptor antagonist macitentan on haemodynamic parameters and NT-proBNP levels and their association with disease progression in patients with pulmonary arterial hypertension  Journal Articles
• Salvage Therapy with Sofosbuvir/Velpatasvir/Voxilaprevir in DAA-experienced Patients: Results from a Prospective Canadian Registry  Journal Articles
• Seizures, headache and thrombocytopenia: diagnosis and treatment do not always come in a standard sequence  Journal Articles
• Spindle epithelial tumor with thymus-like elements of the thyroid: a multi-institutional case series and review of the literature  Journal Articles
• Sulfa or Sulfur? Clearing Things up  Journal Articles
• TGFβ-induced RhoA activation and fibronectin production in mesangial cells require caveolae  Journal Articles
• Targeted therapy for metastatic renal cell carcinoma  Journal Articles
• Targeting endothelin 1 receptor-miR-200b/c-ZEB1 circuitry blunts metastatic progression in ovarian cancer  Journal Articles
• The Additive Effect of Topical Dorzolamide and Systemic Acetazolamide in Pediatric Glaucoma  Journal Articles
• The endothelin-1-driven tumor-stroma feed-forward loops in high-grade serous ovarian cancer  Journal Articles
• The serological profile of fondaparinux-associated heparin-induced thrombocytopenia syndrome  Journal Articles
• Therapeutic effects of the endothelin receptor antagonist Ro 48-5695 in the TNBS/DNBS rat model of colitis  Journal Articles
• Therapy for relapsed multiple myeloma  Journal Articles
• Thrombotic End Point for Assessing Argatroban Therapy for Heparin-Induced Thrombocytopenia  Journal Articles
• Translational Success Stories  Journal Articles
• Treatment for gastrointestinal and pancreatic neuroendocrine tumours: a network meta-analysis  Journal Articles
• Treatment of Heparin-Induced Thrombocytopenia  Journal Articles
• Unleashing Blocked Apoptosis in Cancer Cells: New MCL1 Inhibitors Find Their Groove  Journal Articles
• Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases  Journal Articles
• Vemurafenib-induced radiation recall dermatitis: case report and review of the literature. - PubMed - NCBI  Other
• Venetoclax for the treatment of translocation (11;14) AL amyloidosis  Journal Articles
• Venous limb gangrene and fatal hemorrhage: Adverse consequences of hit “overdiagnosis” in a patient with antiphospholipid syndrome  Journal Articles
• Venous limb gangrene during overlapping therapy with warfarin and a direct thrombin inhibitor for immune heparin‐induced thrombocytopenia  Journal Articles
• hMENA is a key regulator in endothelin-1/β-arrestin1–induced invadopodial function and metastatic process  Journal Articles
• α-channel and calcium-channel blockers are ineffective as medical expulsive therapy for ureteral stones regardless of size and location  Journal Articles
• β-arrestin1/YAP/mutant p53 complexes orchestrate the endothelin A receptor signaling in high-grade serous ovarian cancer  Journal Articles