Receptor, ErbB-2 Concept

subject area of

• 21-Gene Assay to Inform Chemotherapy Benefit in Node-Positive Breast Cancer  Journal Articles
• HER2and Responsiveness of Breast Cancer to Adjuvant Chemotherapy  Journal Articles
• neu/erbB-2 Overexpression and Response to Hormonal Therapy in Premenopausal Women in the Adjuvant Breast Cancer Setting: Will It Play in Peoria? Part II  Journal Articles
• A Novel Approach to Tumor Suppression with Microencapsulated Recombinant Cells  Journal Articles
• A Randomized Trial Comparing 3- versus 4-Monthly Cardiac Monitoring in Patients Receiving Trastuzumab-Based Chemotherapy for Early Breast Cancer  Journal Articles
• A Real-World Comparison Between Adjuvant Docetaxel with Cyclophosphamide (TC) and Anthracycline-Taxane Chemotherapy in Early HER-2 Negative Breast Cancer.  Journal Articles
• A kinome drug screen identifies multi-TKI synergies and ERBB2 signaling as a therapeutic vulnerability in MYC/TYR subgroup atypical teratoid rhabdoid tumors  Journal Articles
• A machine learning approach to radiogenomics of breast cancer: a study of 922 subjects and 529 DCE-MRI features  Journal Articles
• A randomized phase II study of weekly paclitaxel with or without pelareorep in patients with metastatic breast cancer: final analysis of Canadian Cancer Trials Group IND.213.  Journal Articles
• Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer  Journal Articles
• Adjuvant trastuzumab for HER2-positive breast cancer  Journal Articles
• Adoptive immunotherapy of prostate cancer bone lesions using redirected effector lymphocytes  Journal Articles
• Advancing Novel Molecular Imaging Agents from Preclinical Studies to First-in-Humans Phase I Clinical Trials in Academia—A Roadmap for Overcoming Perceived Barriers  Journal Articles
• An Evaluation of the Safety of Continuing Trastuzumab Despite Overt Left Ventricular Dysfunction  Journal Articles
• Analysis of ductal carcinoma in situ by self-reported race reveals molecular differences related to outcome.  Journal Articles
• Anthracyclines in Early Breast Cancer  Journal Articles
• Association Between 21-Gene Assay Recurrence Score and Locoregional Recurrence Rates in Patients With Node-Positive Breast Cancer  Journal Articles
• Associations between insulin-like growth factors and their binding proteins and other prognostic indicators in breast cancer  Journal Articles
• BRCA2 Mutation-associated Breast Cancers Exhibit a Distinguishing Phenotype Based on Morphology and Molecular Profiles From Tissue Microarrays  Journal Articles
• Black Cohosh Increases Metastatic Mammary Cancer in Transgenic Mice Expressing c-erbB2  Journal Articles
• Blood HER2 and Uromodulin as Causal Mediators of CKD  Journal Articles
• Breast cancer risk factors and HER2 over-expression in tumors.  Journal Articles
• Canadian Cancer Trials Group IND197: a phase II study of foretinib in patients with estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2-negative recurrent or metastatic breast cancer  Journal Articles
• Capecitabine monotherapy as first-line treatment in advanced HER2-normal breast cancer – a nationwide, retrospective study  Journal Articles
• Changes in estrogen receptor, progesterone receptor and Her-2/neu status with time: discordance rates between primary and metastatic breast cancer.  Conferences
• Characterizing Complex Polysera Produced by Antigen-Specific Immunization through the Use of Affinity-Selected Mimotopes  Journal Articles
• Chromosome 17 centromere (CEP17) duplication as a predictor of anthracycline response: evidence from the NCIC Clinical Trials Group (NCIC CTG) MA.5 Trial  Journal Articles
• Circulating Tumor DNA as a Predictive Biomarker for Clinical Outcomes With Margetuximab and Pembrolizumab in Pretreated HER2-Positive Gastric/ Gastroesophageal Adenocarcinoma  Journal Articles
• Clinical and Genomic Risk to Guide the Use of Adjuvant Therapy for Breast Cancer  Journal Articles
• Combining Oncolytic HSV-1 with Immunogenic Cell Death-Inducing Drug Mitoxantrone Breaks Cancer Immune Tolerance and Improves Therapeutic Efficacy  Journal Articles
• Comparison of HER2 Dual-Color and Fluorescence In Situ Hybridization in Breast Cancer  Journal Articles
• Complex rearrangements fuel ER+ and HER2+ breast tumours.  Journal Articles
• DARPP-32 and t-DARPP in the development of resistance to anti-HER2 agents. Pre-clinical evidence from the STEP study  Journal Articles
• Defining Breast Cancer Intrinsic Subtypes by Quantitative Receptor Expression  Journal Articles
• Development of Potent Forchlorfenuron Analogs and Their Cytotoxic Effect in Cancer Cell Lines.  Journal Articles
• Developmental and Lactational Exposure to Dieldrin Alters Mammary Tumorigenesis in Her2/neu Transgenic Mice  Journal Articles
• Discordance between Immunohistochemistry and Erb-B2 Receptor Tyrosine Kinase 2 mRNA to Determine Human Epidermal Growth Factor Receptor 2 Low Status for Breast Cancer  Journal Articles
• Discordance between Receptor Status in Primary and Metastatic Breast Cancer: an Exploratory Study of Bone and Bone Marrow Biopsies  Journal Articles
• Dual-Agent Molecular Targeting of the ErbB2 Receptor: Killing One Bird With Two Stones  Journal Articles
• Effect of Metformin vs Placebo on Invasive Disease–Free Survival in Patients With Breast Cancer  Journal Articles
• Effectiveness of Adding Everolimus to the First-line Treatment of Advanced Breast Cancer in Premenopausal Women Who Experienced Disease Progression While Receiving Selective Estrogen Receptor Modulators  Journal Articles
• Efficacy, Safety, and Immunogenicity of HLX02 Compared with Reference Trastuzumab in Patients with Recurrent or Metastatic HER2-Positive Breast Cancer: A Randomized Phase III Equivalence Trial  Journal Articles
• Enhanced HER-2/neu-specific antitumor immunity by cotransduction of mouse dendritic cells with two genes encoding HER-2/neu and alpha tumor necrosis factor  Journal Articles
• Epidermal growth factor receptor-dependent activation of Gab1 is involved in ErbB-2-mediated mammary tumor progression  Journal Articles
• Epirubicin in Breast Cancer: Present and Future  Journal Articles
• ErbB2 IS A TUMOR ASSOCIATED ANTIGEN AND A SUITABLE THERAPEUTIC TARGET IN WILMS TUMOR  Journal Articles
• ErbB2 Is Required for Muscle Spindle and Myoblast Cell Survival  Journal Articles
• ErbB2 enhances mammary tumorigenesis, oncogene-independent recurrence and metastasis in a model of IGF-IR-mediated mammary tumorigenesis  Journal Articles
• Ex vivo expanded natural killer cells from breast cancer patients and healthy donors are highly cytotoxic against breast cancer cell lines and patient-derived tumours  Journal Articles
• Exclusion of Patients With Brain Metastases in Published Phase III Clinical Trials for Advanced Breast Cancer  Journal Articles
• Expression of EGFR, HER-2/neu and KIT in germ cell tumours  Journal Articles
• Expression of HER2neu in Ductal Carcinoma in situ is Associated with Local Recurrence  Journal Articles
• Expression of c-erb B-2 oncogene product in persistent gestational trophoblastic disease  Journal Articles
• Factors influencing survival among patients with HER2-positive metastatic breast cancer treated with trastuzumab  Journal Articles
• Fluorescence in situ hybridization gene amplification analysis of EGFR and HER2 in patients with malignant salivary gland tumors treated with lapatinib  Journal Articles
• Genetic identification of effectors downstream of Neu (ErbB-2) autophosphorylation sites in a Drosophila model  Journal Articles
• Germline-mediated immunoediting sculpts breast cancer subtypes and metastatic proclivity  Journal Articles
• Guidance for Canadian Breast Cancer Practice: National Consensus Recommendations for the Systemic Treatment of Patients with HER2+ Breast Cancer in Both the Early and Metastatic Setting.  Journal Articles
• HER2 Testing in a Population-Based Study of Patients With Metastatic Breast Cancer Treated With Trastuzumab  Journal Articles
• HER2/Neu and the Ets transcription activator PEA3 are coordinately upregulated in human breast cancer  Journal Articles
• Herceptest: Her2 expression and gene amplification in non-small cell lung cancer  Journal Articles
• Hormone Receptor and ERBB2 Status in Gene Expression Profiles of Human Breast Tumor Samples  Journal Articles
• INHIBITION OF WILMS TUMOR XENOGRAFT PROGRESSION BY HALOFUGINONE IS ACCOMPANIED BY ACTIVATION OF WT-1 GENE EXPRESSION  Conferences
• Identification of a Low-Risk Luminal A Breast Cancer Cohort That May Not Benefit From Breast Radiotherapy  Journal Articles
• Identification of a Novel Luminal Molecular Subtype of Breast Cancer  Journal Articles
• Immuno-gene therapy of established prostate tumors using chimeric receptor-redirected human lymphocytes.  Journal Articles
• Immunofluorometric analysis of p53 protein and prostate-specific antigen in breast tumours and their association with other prognostic indicators  Journal Articles
• Immunogenic HSV-mediated Oncolysis Shapes the Antitumor Immune Response and Contributes to Therapeutic Efficacy  Journal Articles
• Impaired c-src activation and motility defects in PEA3-null fibroblasts  Journal Articles
• Incidence of Brain Metastases in Nonmetastatic and Metastatic Breast Cancer: Is There a Role for Screening?  Journal Articles
• Induction of ErbB-2/neu-specific protective and therapeutic antitumor immunity using genetically modified dendritic cells: enhanced efficacy by cotransduction of gene encoding IL-12  Journal Articles
• Induction of specific human cytotoxic T cells using dendritic cells transduced with an adenovector encoding rat epidermal growth factor receptor 2  Journal Articles
• Intra-tumor molecular heterogeneity in breast cancer: definitions of measures and association with distant recurrence-free survival  Journal Articles
• Intratumoral administration of an adenovirus expressing a kinase dead form of ErbB-2 inhibits tumor growth  Journal Articles
• Invasive lobular carcinoma: to grade or not to grade  Journal Articles
• Lapatinib or Trastuzumab Plus Taxane Therapy for Human Epidermal Growth Factor Receptor 2–Positive Advanced Breast Cancer: Final Results of NCIC CTG MA.31  Journal Articles
• Lapatinib-Related Rash and Breast Cancer Outcome in the ALTTO Phase III Randomized Trial  Journal Articles
• Loss of Antigenicity in Stored Sections of Breast Cancer Tissue Microarrays  Journal Articles
• Margetuximab plus pembrolizumab in patients with previously treated, HER2-positive gastro-oesophageal adenocarcinoma (CP-MGAH22–05): a single-arm, phase 1b–2 trial  Journal Articles
• Mesenchymal Stromal Cells Expressing ErbB-2/neu Elicit Protective Antibreast Tumor Immunity In vivo, Which Is Paradoxically Suppressed by IFN-γ and Tumor Necrosis Factor-α Priming  Journal Articles
• Micronutrients Involved in One-Carbon Metabolism and Risk of Breast Cancer Subtypes  Journal Articles
• Multivariate machine learning models for prediction of pathologic response to neoadjuvant therapy in breast cancer using MRI features: a study using an independent validation set  Journal Articles
• Novel method for differentiation between Trastuzumab and host adaptive response  Journal Articles
• Nuclear Kaiso Expression Is Associated with High Grade and Triple-Negative Invasive Breast Cancer  Journal Articles
• Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: a phase 2, multicentre, open-label, non-randomised study  Journal Articles
• Omitting Radiotherapy after Breast-Conserving Surgery in Luminal A Breast Cancer  Journal Articles
• Omitting Radiotherapy in Luminal A Breast Cancer  Journal Articles
• Omitting Radiotherapy in Luminal A Breast Cancer.  Journal Articles
• Palbociclib plus letrozole versus placebo plus letrozole in Asian postmenopausal women with oestrogen receptor–positive/human epidermal growth factor receptor 2–negative advanced breast cancer: Primary results from PALOMA-4  Journal Articles
• Pegylated Liposomal Doxorubicin and Trastuzumab in HER-2 Overexpressing Metastatic Breast Cancer: A Multicenter Phase II Trial  Conferences
• Performance of preoperative breast MRI based on breast cancer molecular subtype  Journal Articles
• Perspectives on shorter durations of anti-HER2 therapy in early-stage HER2-positive breast cancer: a patient survey  Journal Articles
• Pharmacokinetics, safety, activity, and biomarker analysis of palbociclib plus letrozole as first-line treatment for ER+/HER2– advanced breast cancer in Chinese women  Journal Articles
• Phase I/randomized phase II study of afatinib, an irreversible ErbB family blocker, with or without protracted temozolomide in adults with recurrent glioblastoma  Journal Articles
• Plant-Produced Trastuzumab Inhibits the Growth of HER2 Positive Cancer Cells  Journal Articles
• Predictive Significance of an Optimized Panel for Basal-like Breast Cancer: Results from the Canadian Cancer Trials Group MA.5 and MA.12 Phase III Clinical Trials  Journal Articles
• Prognostic value of the trichorhinophalangeal syndrome-1 (TRPS-1), a GATA family transcription factor, in early-stage breast cancer  Journal Articles
• Prospective Evaluation of the 21-Gene Recurrence Score Assay for Breast Cancer Decision-Making in Ontario  Journal Articles
• Prospective Validation of a 21-Gene Expression Assay in Breast Cancer  Journal Articles
• Race, Ethnicity, and Clinical Outcomes in Hormone Receptor-Positive, HER2-Negative, Node-Negative Breast Cancer in the Randomized TAILORx Trial  Journal Articles
• Recommendations from the European Commission Initiative on Breast Cancer for multigene testing to guide the use of adjuvant chemotherapy in patients with early breast cancer, hormone receptor positive, HER-2 negative  Journal Articles
• Refined histopathological predictors of BRCA1 and BRCA2mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia  Journal Articles
• Requirement for Both Shc and Phosphatidylinositol 3′ Kinase Signaling Pathways in Polyomavirus Middle T-Mediated Mammary Tumorigenesis  Journal Articles
• Responsiveness of Intrinsic Subtypes to Adjuvant Anthracycline Substitution in the NCIC.CTG MA.5 Randomized Trial  Journal Articles
• Role of Ets transcription factors in mammary gland development and oncogenesis.  Journal Articles
• Safety of Treatment of Metastatic Breast Cancer With Trastuzumab Beyond Disease Progression  Journal Articles
• Salad vegetables dietary pattern protects against HER‐2‐positive breast cancer: A prospective Italian study  Journal Articles
• Scavenging of Extracellular H2O2 by Catalase Inhibits the Proliferation of HER-2/Neu-transformed Rat-1 Fibroblasts through the Induction of a Stress Response  Journal Articles
• Secretory Breast Carcinoma: Unique, Triple-Negative Carcinoma With a Favorable Prognosis and Characteristic Molecular Expression  Journal Articles
• Sex Hormone Levels, Breast Cancer Risk, and Cancer Receptor Status in Postmenopausal Women: the ORDET Cohort  Journal Articles
• Shorter Durations of Anti-HER2 Therapy for Patients with Early-Stage, HER2-Positive Breast Cancer: The Physician Perspective  Journal Articles
• Small Molecule Antagonists of the Wnt/Beta-Catenin Signaling Pathway Target Breast Tumor-Initiating Cells in a Her2/Neu Mouse Model of Breast Cancer  Journal Articles
• Tailoring therapies—improving the management of early breast cancer: St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2015  Journal Articles
• The Effect of Metformin vs Placebo on Sex Hormones in Canadian Cancer Trials Group MA.32  Journal Articles
• The HER-2/neu oncogene in breast cancer: so what is new?  Journal Articles
• The Omission of Anthracycline Chemotherapy in Women with Early HER2-Negative Breast Cancer—A Systematic Review and Meta-Analysis  Journal Articles
• The PEA3 Ets transcription factor is a downstream target of the HER2/Neu receptor tyrosine kinase  Journal Articles
• The Role of HER-2/neu Oncogene and Vimentin Filaments in the Production of the Paget's Phenotype  Journal Articles
• The chimeric TAC receptor co-opts the T cell receptor yielding robust anti-tumor activity without toxicity  Journal Articles
• The effects of lymph node status on predicting outcome in ER+ /HER2- tamoxifen treated breast cancer patients using gene signatures  Journal Articles
• The incidence of brain metastases among patients with metastatic breast cancer: a systematic review and meta-analysis.  Journal Articles
• The pea3 subfamily ets genes are required for HER2/Neu-mediated mammary oncogenesis  Journal Articles
• The role of circulating extracellular vesicles in breast cancer classification and molecular subtyping  Journal Articles
• Three-Year Outcomes Following Permissive Cardiotoxicity in Patients on Trastuzumab  Journal Articles
• Thyroid hormone receptor α in breast cancer: prognostic and therapeutic implications  Journal Articles
• Topoisomerase II alpha protein and responsiveness of breast cancer to adjuvant chemotherapy with CEF compared to CMF in the NCIC CTG randomized MA.5 adjuvant trial  Journal Articles
• Trastuzumab Cardiac Side Effects: Only Time Will Tell  Journal Articles
• Trastuzumab emtansine (T-DM1) versus trastuzumab in Chinese patients with residual invasive disease after neoadjuvant chemotherapy and HER2-targeted therapy for HER2-positive breast cancer in the phase 3 KATHERINE study  Journal Articles
• Trastuzumab for early-stage, HER2-positive breast cancer: a meta-analysis of 13 864 women in seven randomised trials  Journal Articles
• Tumor Protection Following Vaccination With Low Doses of Lentivirally Transduced DCs Expressing the Self-antigen erbB2  Journal Articles