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The Omission of Anthracycline Chemotherapy in...
Journal article

The Omission of Anthracycline Chemotherapy in Women with Early HER2-Negative Breast Cancer—A Systematic Review and Meta-Analysis

Abstract

BACKGROUND: Anthracycline-taxane is the standard chemotherapy strategy for treating high-risk early breast cancer despite the potentially life-threatening adverse events caused by anthracyclines. Commonly, the combination of docetaxel and cyclophosphamide (TC) is considered an alternative option. However, the efficacy of TC compared to anthracycline-taxane chemotherapy is unclear. This study compares disease-free survival (DFS), overall …

Authors

de Mello Morais Mata DG; Rush M-B; Smith-Uffen M; Younus J; Lohmann AE; Trudeau M; Morgan RL

Journal

Current Oncology, Vol. 31, No. 8, pp. 4486–4506

Publisher

MDPI

DOI

10.3390/curroncol31080335

ISSN

1198-0052