Journal article
The Role of HER‐2/neu Oncogene and Vimentin Filaments in the Production of the Paget's Phenotype
Abstract
The histogenesis as well as the biological and molecular differences in mammary Paget's disease (MPD) and extramammary Paget's disease (EPD) are not well understood. HER-2/neu oncogene overexpression is associated with poor prognosis in breast cancer patients. It is also believed that the spread of Paget's cells through the epidermis is induced by a motility factor that acts via the HER-2/neu receptor. However, previous studies on HER-2/neu …
Authors
Hanna W; Alowami S; Malik A
Journal
The Breast Journal, Vol. 9, No. 6, pp. 485–490
Publisher
Hindawi
Publication Date
November 2003
DOI
10.1046/j.1524-4741.2003.09610.x
ISSN
1075-122X