Protein Structure, Secondary Concept

subject area of

• A Cytosolic Amphiphilic α-Helix Controls the Activity of the Bile Acid-sensitive Ion Channel (BASIC)  Journal Articles
• A Highly Dynamic Loop of the Pseudomonas aeruginosa PA14 Type IV Pilin Is Essential for Pilus Assembly  Journal Articles
• A Model for Agonism and Antagonism in an Ancient and Ubiquitous cAMP-binding Domain  Journal Articles
• A Mutation in the Intracellular Loop III/IV of Mosquito Sodium Channel Synergizes the Effect of Mutations in Helix IIS6 on Pyrethroid Resistance  Journal Articles
• A Refined Model for the Somatostatin Pharmacophore:  Conformational Analysis of Lanthionine−Sandostatin Analogs  Journal Articles
• A Thermal-Cycling Method for Disaggregating Monoclonal Antibody Oligomers  Journal Articles
• Alignment/Phylogeny of the Papain Superfamily of Cysteine Proteases  Journal Articles
• All three Ca²⁺‐binding loops of photoproteins bind calcium ions: The crystal structures of calcium‐loaded apo‐aequorin and apo‐obelin  Journal Articles
• Allosteric Modulation of the Dopamine D₂ Receptor by Pro-Leu-Gly-NH₂ Peptidomimetics Constrained in Either a Polyproline II Helix or a Type II β-Turn Conformation  Journal Articles
• Allosteric Modulation of the Dopamine Receptor by Conformationally Constrained Type VI β-Turn Peptidomimetics of Pro-Leu-Gly-NH₂  Journal Articles
• Amyloid-β_25–35peptides aggregate into cross-β sheets in unsaturated anionic lipid membranes at high peptide concentrations  Journal Articles
• An Apolipoprotein AI Mimetic Peptide:  Membrane Interactions and the Role of Cholesterol^,  Journal Articles
• Atomic-resolution map of the interactions between an amyloid inhibitor protein and amyloid β (Aβ) peptides in the monomer and protofibril states  Journal Articles
• Backbone and side-chain resonance assignments of Plasmodium falciparum SUMO  Journal Articles
• Bacterial Chemotaxis: The motor connection  Journal Articles
• Binding of reovirus to receptor leads to conformational changes in viral capsid proteins that are reversible upon virus detachment.  Journal Articles
• Bone recognition mechanism of porcine osteocalcin from crystal structure  Journal Articles
• Characterizing the Secondary Structure and Identifying Functionally Essential Nucleotides of pH6DZ1, a Fluorescence-Signaling and RNA-Cleaving Deoxyribozyme  Journal Articles
• Chemical and biosynthetic evolution of the antimycin-type depsipeptides  Journal Articles
• Collagen-Based Structures Containing the Peptoid Residue N-Isobutylglycine (Nleu):  Conformational Analysis of Gly-Nleu-Pro Sequences by ¹H-NMR and Molecular Modeling  Journal Articles
• Collagen-Based Structures Containing the Peptoid ResidueN-Isobutylglycine (Nleu):  Synthesis and Biophysical Studies of Gly-Nleu-Pro Sequences by Circular Dichroism and Optical Rotation  Journal Articles
• Comparison of mammalian and bacterial expression library screening to detect recombinant alpha-1 proteinase inhibitor variants with enhanced thrombin inhibitory capacity☆  Journal Articles
• Conformation of a double-membrane-spanning fragment of a G protein-coupled receptor: Effects of hydrophobic environment and pH  Journal Articles
• Conservation and variability of the pore-lining helices in P-loop channels  Journal Articles
• Conserved, unstructured regions in Pseudomonas aeruginosa PilO are important for type IVa pilus function  Journal Articles
• D-TACC: a novel centrosomal protein required for normal spindle function in the early Drosophila embryo.  Journal Articles
• Design, Synthesis, and Dopamine Receptor Modulating Activity of Spiro Bicyclic Peptidomimetics ofl-Prolyl-l-leucyl-glycinamide  Journal Articles
• Detergent-mediated protein aggregation  Journal Articles
• Dimerization and interactions of Brucella suis VirB8 with VirB4 and VirB10 are required for its biological activity  Journal Articles
• Domain−Domain Interactions in the Aminoglycoside Antibiotic Resistance Enzyme AAC(6‘)-APH(2‘ ‘)  Journal Articles
• Dopamine D4 receptor variant, D4GLYCINE194, in Africans, but not in Caucasians: No association with Schizophrenia  Journal Articles
• During Apoptosis Bcl-2 Changes Membrane Topology at Both the Endoplasmic Reticulum and Mitochondria  Journal Articles
• Effects of Cu Ions and Explicit Water Molecules on the Copper Binding Domain of Amyloid Precursor Protein APP(131–189): A Molecular Dynamics Study  Journal Articles
• Effects of metal binding affinity on the chemical and thermal stability of site-directed mutants of rat oncomodulin  Journal Articles
• Entropy-driven cAMP-dependent Allosteric Control of Inhibitory Interactions in Exchange Proteins Directly Activated by cAMP  Journal Articles
• Evolution of Allosteric Control in Glycogen Phosphorylase  Journal Articles
• Expression and spectroscopic characterization of a large fragment of the μ-opioid receptor  Journal Articles
• Full or Partial Substitution of the Reactive Center Loop of α-1-Proteinase Inhibitor by that of Heparin Cofactor II:  P1 Arg Is Required for Maximal Thrombin Inhibition  Journal Articles
• Gauging a Hydrocarbon Ruler by an Intrinsic Exciton Probe  Journal Articles
• Helix Induction in Antimicrobial Peptides by Alginate in Biofilms  Journal Articles
• Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity  Journal Articles
• Identification and characterization of a factor Va-binding site on human prothrombin fragment 2  Journal Articles
• Identification of a Karyopherin β1/β2 Proline-Tyrosine Nuclear Localization Signal in Huntingtin Protein  Journal Articles
• Identification of the Endoplasmic Reticulum Targeting Signal in Vesicle-associated Membrane Proteins  Journal Articles
• Identification of the Mechanism Responsible for the Increased Fibrin Specificity of TNK-Tissue Plasminogen Activator Relative to Tissue Plasminogen Activator  Journal Articles
• Importance of the spatial display of charged residues in heparin–peptide interactions  Journal Articles
• Induction of Flexibility through Protein-Protein Interactions  Journal Articles
• Interaction of oxytocin with Ca2+: I. CD and fluorescence spectral characterization and comparison with vasopressin.  Journal Articles
• Kinked-Helices Model of the Nicotinic Acetylcholine Receptor Ion Channel and Its Complexes with Blockers: Simulation by the Monte Carlo Minimization Method  Journal Articles
• Lipid Trafficking Controls Endotoxin Acylation in Outer Membranes of Escherichia coli  Journal Articles
• Local Structural Preferences and Dynamics Restrictions in the Urea-Denatured State of SUMO-1: NMR Characterization  Journal Articles
• Maintenance of caspase-3 proenzyme dormancy by an intrinsic “safety catch” regulatory tripeptide  Journal Articles
• Membrane interactions of the hydrophobic segment of diacylglycerol kinase epsilon  Journal Articles
• Modeling interactions between blocking and permeant cations in the NavMs channel  Journal Articles
• Molecular Dynamics of Fibrinogen Adsorption onto Graphene, but Not onto Poly(ethylene glycol) Surface, Increases Exposure of Recognition Sites That Trigger Immune Response  Journal Articles
• Multiconformational NMR Analysis of Sandostatin (Octreotide):  Equilibrium between β-Sheet and Partially Helical Structures^,  Journal Articles
• Mutagenesis and peptide analysis of the DRY motif in the α2A adrenergic receptor: evidence for alternate mechanisms in G protein-coupled receptors  Journal Articles
• NMR Structure of the Second Intracellular Loop of the α2A Adrenergic Receptor:  Evidence for a Novel Cytoplasmic Helix^,  Journal Articles
• Orientation and Effects of Mastoparan X on Phospholipid Bicelles  Journal Articles
• Orientation and helical conformation of a tissue‐specific hunter‐killer peptide in micelles  Journal Articles
• Peptides that form β‐sheets on hydrophobic surfaces accelerate surface‐induced insulin amyloidal aggregation  Journal Articles
• Periplasmic Domains of Pseudomonas aeruginosa PilN and PilO Form a Stable Heterodimeric Complex  Journal Articles
• PilF Is an Outer Membrane Lipoprotein Required for Multimerization and Localization of thePseudomonas aeruginosaType IV Pilus Secretin  Journal Articles
• Possible Roles of Exceptionally Conserved Residues around the Selectivity Filters of Sodium and Calcium Channels  Journal Articles
• Potassium Channel Block by a Tripartite Complex of Two Cationophilic Ligands and a Potassium Ion  Journal Articles
• Presence of Alanine-to-Valine Substitutions in Myofibrillogenesis Regulator 1 in Paroxysmal Nonkinesigenic Dyskinesia  Journal Articles
• Pseudomonas aeruginosa Minor Pilins Prime Type IVa Pilus Assembly and Promote Surface Display of the PilY1 Adhesin  Journal Articles
• Quantitative Mapping of the Orientation of Fibroin β-Sheets in B. mori Cocoon Fibers by Scanning Transmission X-ray Microscopy  Journal Articles
• Review: Modulating Factors in Amyloid-β Fibril Formation  Journal Articles
• Rifampin phosphotransferase is an unusual antibiotic resistance kinase  Journal Articles
• Rifamycin antibiotic resistance by ADP-ribosylation: Structure and diversity of Arr  Journal Articles
• Role of the Hydrophobic Segment of Diacylglycerol Kinase ε  Journal Articles
• Rotational Symmetry of Two Pyrethroid Receptor Sites in the Mosquito Sodium Channel  Journal Articles
• Self-Assembly Enhances the Strength of Fibers Made from Vimentin Intermediate Filament Proteins  Journal Articles
• Serpin Phage Display: The Use of a T7 System to Probe Reactive Center Loop Libraries with Different Serine Proteinases  Journal Articles
• Solution structure and dynamics of the outer membrane enzyme PagP by NMR  Journal Articles
• Spontaneously Forming Ellipsoidal Phospholipid Unilamellar Vesicles and Their Interactions with Helical Domains of Saposin C  Journal Articles
• Stationary Phase Expression of a Novel Escherichia coli Outer Membrane Lipoprotein and Its Relationship with Mammalian Apolipoprotein D  Journal Articles
• Structural Characterization of Novel Pseudomonas aeruginosa Type IV Pilins  Journal Articles
• Structural Characterization of a Novel Chlamydia pneumoniae Type III Secretion-Associated Protein, Cpn0803  Journal Articles
• Structural Insights into the Regulation of Foreign Genes in Salmonella by the Hha/H-NS Complex  Journal Articles
• Structural and Functional Interaction between the Human DNA Repair Proteins DNA Ligase IV and XRCC4  Journal Articles
• Structural basis for alginate secretion across the bacterial outer membrane  Journal Articles
• Structural biology of membrane-intrinsic β-barrel enzymes: Sentinels of the bacterial outer membrane  Journal Articles
• Structural model of a synthetic Ca2+ channel with bound Ca2+ ions and dihydropyridine ligand  Journal Articles
• Structure and Protein-Protein Interaction Studies on Chlamydia trachomatis Protein CT670 (YscO Homolog)  Journal Articles
• Structure of an Enzyme Required for Aminoglycoside Antibiotic Resistance Reveals Homology to Eukaryotic Protein Kinases  Journal Articles
• Structure of human phosphatidylcholine transfer protein in complex with its ligand.  Journal Articles
• Structure of the Cytoplasmic Region of PelD, a Degenerate Diguanylate Cyclase Receptor That Regulates Exopolysaccharide Production in Pseudomonas aeruginosa  Journal Articles
• Studies of a putative ice‐binding motif in winter flounder skin‐type anti‐freeze polypeptide  Journal Articles
• Symbiotic nitrogen fixation by a nifA deletion mutant of Rhizobium meliloti: the role of an unusual ntrC allele  Journal Articles
• Synthesis and Dopamine Receptor Modulating Activity of Novel Peptidomimetics ofl-Prolyl-l-leucyl-glycinamide Featuring α,α-Disubstituted Amino Acids  Journal Articles
• Synthesis and characterization of a fragment of an ice nucleation protein  Journal Articles
• The Auto-Inhibitory Role of the EPAC Hinge Helix as Mapped by NMR  Journal Articles
• The BH3 domain of BAD fused to the Antennapedia peptide induces apoptosis via its alpha helical structure and independent of Bcl-2  Journal Articles
• The COOH terminus of aminoglycoside phosphotransferase (3')-IIIa is critical for antibiotic recognition and resistance  Journal Articles
• The Pattern of Amino Acid Replacements in α/β-Barrels  Journal Articles
• The Projection Analysis of NMR Chemical Shifts Reveals Extended EPAC Autoinhibition Determinants  Journal Articles
• The Roles of Selected Arginine and Lysine Residues of TAFI (Pro-CPU) in Its Activation to TAFIa by the Thrombin-Thrombomodulin Complex  Journal Articles
• The Solution Conformational Features of Two Highly Homologous Antigenic Peptides of Foot‐and‐mouth Disease Virus Serotype A, Variants A and USA, Correlate with their Serological Properties  Journal Articles
• The cDNA Sequence of Human Endothelial Cell Multimerin  Journal Articles
• The solution structure of Lac repressor headpiece 62 complexed to a symmetrical lac operator  Journal Articles
• Type IV Pilin Proteins: Versatile Molecular Modules  Journal Articles
• Understanding ribosome assembly: the structure of in vivo assembled immature 30S subunits revealed by cryo-electron microscopy  Journal Articles
• Unraveling Determinants of Affinity Enhancement in Dimeric Aptamers for a Dimeric Protein  Journal Articles
• Water-macromolecule interactions by NMR: a quadrature-free constant-time approach and its application to CI2.  Journal Articles
• Why Does the Inner-Helix Mutation A413C Double the Stoichiometry of Kv1.3 Channel Block by Emopamil but Not by Verapamil?  Journal Articles
• YphC and YsxC GTPases assist the maturation of the central protuberance, GTPase associated region and functional core of the 50S ribosomal subunit  Journal Articles