Protein Structure, Secondary Concept

subject area of

• A Cytosolic Amphiphilic α-Helix Controls the Activity of the Bile Acid-sensitive Ion Channel (BASIC)  Academic Article
• A Model for Agonism and Antagonism in an Ancient and Ubiquitous cAMP-binding Domain  Academic Article
• A Mutation in the Intracellular Loop III/IV of Mosquito Sodium Channel Synergizes the Effect of Mutations in Helix IIS6 on Pyrethroid Resistance  Academic Article
• A Novel Linear Amphipathic β-Sheet Cationic Antimicrobial Peptide with Enhanced Selectivity for Bacterial Lipids  Academic Article
• A Refined Model for the Somatostatin Pharmacophore:  Conformational Analysis of Lanthionine−Sandostatin Analogs  Academic Article
• A Thermal-Cycling Method for Disaggregating Monoclonal Antibody Oligomers  Academic Article
• Alamethicin Pyromellitate: An Ion-Activated Channel-Forming Peptide  Academic Article
• Alignment/Phylogeny of the Papain Superfamily of Cysteine Proteases  Academic Article
• All three Ca2+-binding loops of photoproteins bind calcium ions: The crystal structures of calcium-loaded apo-aequorin and apo-obelin  Academic Article
• Allosteric Modulation of the Dopamine D2Receptor by Pro-Leu-Gly-NH2Peptidomimetics Constrained in Either a Polyproline II Helix or a Type II β-Turn Conformation  Academic Article
• Allosteric Modulation of the Dopamine Receptor by Conformationally Constrained Type VI β-Turn Peptidomimetics of Pro-Leu-Gly-NH2  Academic Article
• Amphipathic peptide affects the lateral domain organization of lipid bilayers  Academic Article
• Amyloid-β25–35 peptides aggregate into cross-β sheets in unsaturated anionic lipid membranes at high peptide concentrations  Academic Article
• An Apolipoprotein AI Mimetic Peptide:  Membrane Interactions and the Role of Cholesterol†,‡  Academic Article
• Archaeal histones: structures, stability and DNA binding  Conference Paper
• Aromatic Residue Position on the Nonpolar Face of Class A Amphipathic Helical Peptides Determines Biological Activity  Academic Article
• Atomic-resolution map of the interactions between an amyloid inhibitor protein and amyloid β (Aβ) peptides in the monomer and protofibril states  Academic Article
• Bacterial Chemotaxis: The motor connection  Academic Article
• Bacterial species selective toxicity of two isomeric α/β-peptides: Role of membrane lipids  Academic Article
• Caveolin-1 hydrophobic segment peptides insertion into membrane mimetic systems: Role of Proline residue  Academic Article
• Characterizing the Secondary Structure and Identifying Functionally Essential Nucleotides of pH6DZ1, a Fluorescence-Signaling and RNA-Cleaving Deoxyribozyme†  Academic Article
• Chemical and biosynthetic evolution of the antimycin-type depsipeptides  Academic Article
• Circular dichroism (CD) studies of antagonists derived from parathyroid hormone-related protein  Academic Article
• Collagen-Based Structures Containing the Peptoid ResidueN-Isobutylglycine (Nleu):  Conformational Analysis of Gly-Nleu-Pro Sequences by1H-NMR and Molecular Modeling†  Academic Article
• Collagen-Based Structures Containing the Peptoid ResidueN-Isobutylglycine (Nleu):  Synthesis and Biophysical Studies of Gly-Nleu-Pro Sequences by Circular Dichroism and Optical Rotation†  Academic Article
• Comparative Analysis of Membrane-Associated Fusion Peptide Secondary Structure and Lipid Mixing Function of HIV gp41 Constructs that Model the Early Pre-Hairpin Intermediate and Final Hairpin Conformations  Academic Article
• Comparison of mammalian and bacterial expression library screening to detect recombinant alpha-1 proteinase inhibitor variants with enhanced thrombin inhibitory capacity☆  Academic Article
• Composite Active Site of an ABC ATPase  Academic Article
• Conformation of a double-membrane-spanning fragment of a G protein-coupled receptor: Effects of hydrophobic environment and pH  Academic Article
• Conservation and variability of the pore-lining helices in P-loop channels  Academic Article
• Decoding the Functional Roles of Cationic Side Chains of the Major Antimicrobial Region of Human Cathelicidin LL-37  Academic Article
• Design, Synthesis, and Dopamine Receptor Modulating Activity of Spiro Bicyclic Peptidomimetics ofl-Prolyl-l-leucyl-glycinamide  Academic Article
• Detergent-mediated protein aggregation  Academic Article
• Direct comparison of membrane interactions of model peptides composed of only Leu and Lys residues  Academic Article
• Domain−Domain Interactions in the Aminoglycoside Antibiotic Resistance Enzyme AAC(6‘)-APH(2‘ ‘)†  Academic Article
• Dopamine D4 receptor variant, D4GLYCINE194, in Africans, but not in Caucasians: No association with Schizophrenia  Academic Article
• During Apoptosis Bcl-2 Changes Membrane Topology at Both the Endoplasmic Reticulum and Mitochondria  Academic Article
• Effects of Cu Ions and Explicit Water Molecules on the Copper Binding Domain of Amyloid Precursor Protein APP(131–189): A Molecular Dynamics Study  Academic Article
• Effects of metal binding affinity on the chemical and thermal stability of site-directed mutants of rat oncomodulin  Academic Article
• Entropy-driven cAMP-dependent Allosteric Control of Inhibitory Interactions in Exchange Proteins Directly Activated by cAMP  Academic Article
• Evolution of Allosteric Control in Glycogen Phosphorylase  Academic Article
• Expression and spectroscopic characterization of a large fragment of the μ-opioid receptor  Academic Article
• Expression, Purification, and Properties of a Human Arachidonoyl-Specific Isoform of Diacylglycerol Kinase  Academic Article
• Factors Contributing to the Fusogenic Potency of Foamy Virus  Academic Article
• Full or Partial Substitution of the Reactive Center Loop of α-1-Proteinase Inhibitor by that of Heparin Cofactor II:  P1 Arg Is Required for Maximal Thrombin Inhibition  Academic Article
• Gauging a Hydrocarbon Ruler by an Intrinsic Exciton Probe†  Academic Article
• Growth hormone-releasing factor analogs with hydrophobic residues at position 19. Effects on growth hormone releasing activity in vitro and in vivo, stability in blood plasma in vitro, and secondary structure  Academic Article
• Helix Induction in Antimicrobial Peptides by Alginate in Biofilms  Academic Article
• Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity  Academic Article
• Identification of a Karyopherin β1/β2 Proline-Tyrosine Nuclear Localization Signal in Huntingtin Protein  Academic Article
• Identification of the Endoplasmic Reticulum Targeting Signal in Vesicle-associated Membrane Proteins  Academic Article
• Identification of the Mechanism Responsible for the Increased Fibrin Specificity of TNK-Tissue Plasminogen Activator Relative to Tissue Plasminogen Activator  Academic Article
• Induction of Flexibility through Protein-Protein Interactions  Academic Article
• Influence of the Angle Subtended by the Positively Charged Helix Face on the Membrane Activity of Amphipathic, Antibacterial Peptides†  Academic Article
• Interaction of oxytocin with Ca2+: I. CD and fluorescence spectral characterization and comparison with vasopressin.  Academic Article
• Irreversible Unfolding of the Neutral pH Form of Influenza Hemagglutinin Demonstrates That It Is Not in a Metastable State†  Academic Article
• Kinked-Helices Model of the Nicotinic Acetylcholine Receptor Ion Channel and Its Complexes with Blockers: Simulation by the Monte Carlo Minimization Method  Academic Article
• Lipid Trafficking Controls Endotoxin Acylation in Outer Membranes ofEscherichia coli  Academic Article
• Lipid clustering by three homologous arginine-rich antimicrobial peptides is insensitive to amino acid arrangement and induced secondary structure  Academic Article
• Lysophosphatidylcholine mediates the mode of insertion of the NH2 -terminal SIV fusion peptide into the lipid bilayer  Academic Article
• Mechanisms for the modulation of membrane bilayer properties by amphipathic helical peptides  Academic Article
• Membrane Interactions of Mutated Forms of the Influenza Fusion Peptide†  Academic Article
• Membrane activity of an amphiphilic α-Helical membrane-proximal cytoplasmic domain of the MoMuLV envelope glycoprotein  Academic Article
• Membrane interactions of the hydrophobic segment of diacylglycerol kinase epsilon  Academic Article
• Modeling interactions between blocking and permeant cations in the NavMs channel  Academic Article
• Molecular Dynamics of Fibrinogen Adsorption onto Graphene, but Not onto Poly(ethylene glycol) Surface, Increases Exposure of Recognition Sites That Trigger Immune Response  Academic Article
• Multiconformational NMR Analysis of Sandostatin (Octreotide):  Equilibrium between β-Sheet and Partially Helical Structures†,‡  Academic Article
• Munc18-1: Sequential Interactions with the Fusion Machinery Stimulate Vesicle Docking and Priming  Academic Article
• Mutagenesis and peptide analysis of the DRY motif in the α2A adrenergic receptor: evidence for alternate mechanisms in G protein-coupled receptors  Academic Article
• Myristoylation, a Protruding Loop, and Structural Plasticity Are Essential Features of a Nonenveloped Virus Fusion Peptide Motif  Academic Article
• NMR Structure of the Second Intracellular Loop of the α2A Adrenergic Receptor:  Evidence for a Novel Cytoplasmic Helix†,‡  Academic Article
• Oblique Membrane Insertion of Viral Fusion Peptide Probed by Neutron Diffraction†  Academic Article
• Oral administration of L-mR18L, a single domain cationic amphipathic helical peptide, inhibits lesion formation in ApoE null mice  Academic Article
• Orientation and Effects of Mastoparan X on Phospholipid Bicelles  Academic Article
• Orientation and helical conformation of a tissue-specific hunter-killer peptide in micelles  Academic Article
• Osmotically Induced Membrane Tension Modulates Membrane Permeabilization by Class L Amphipathic Helical Peptides: Nucleation Model of Defect Formation  Academic Article
• Periplasmic Domains of Pseudomonas aeruginosa PilN and PilO Form a Stable Heterodimeric Complex  Academic Article
• PilF Is an Outer Membrane Lipoprotein Required for Multimerization and Localization of the Pseudomonas aeruginosa Type IV Pilus Secretin  Academic Article
• Position-Dependent Hydrophobicity of the Antimicrobial Magainin Peptide Affects the Mode of Peptide−Lipid Interactions and Selective Toxicity†  Academic Article
• Possible Roles of Exceptionally Conserved Residues around the Selectivity Filters of Sodium and Calcium Channels  Academic Article
• Potassium Channel Block by a Tripartite Complex of Two Cationophilic Ligands and a Potassium Ion  Academic Article
• Presence of Alanine-to-Valine Substitutions in Myofibrillogenesis Regulator 1 in Paroxysmal Nonkinesigenic Dyskinesia  Academic Article
• Pseudomonas aeruginosaMinor Pilins Prime Type IVa Pilus Assembly and Promote Surface Display of the PilY1 Adhesin  Academic Article
• Quantitative Mapping of the Orientation of Fibroin β-Sheets inB.moriCocoon Fibers by Scanning Transmission X-ray Microscopy  Academic Article
• Relationship of membrane sidedness to the effects of the lipophosphoglycan of Leishmania donovani on the fusion of influenza virus  Academic Article
• Rifampin phosphotransferase is an unusual antibiotic resistance kinase  Academic Article
• Rifamycin antibiotic resistance by ADP-ribosylation: Structure and diversity of Arr  Academic Article
• Role of Lipids in the Permeabilization of Membranes by Class L Amphipathic Helical Peptides†  Academic Article
• Role of the Hydrophobic Segment of Diacylglycerol Kinase ε†  Academic Article
• Rotational Symmetry of Two Pyrethroid Receptor Sites in the Mosquito Sodium Channel  Academic Article
• Self-Assembly Enhances the Strength of Fibers Made from Vimentin Intermediate Filament Proteins  Academic Article
• Sendai virus N-terminal fusion peptide consists of two similar repeats, both of which contribute to membrane fusion  Academic Article
• Serpin Phage Display: The Use of a T7 System to Probe Reactive Center Loop Libraries with Different Serine Proteinases  Academic Article
• Solution structure and dynamics of the outer membrane enzyme PagP by NMR  Academic Article
• Spontaneously Forming Ellipsoidal Phospholipid Unilamellar Vesicles and Their Interactions with Helical Domains of Saposin C  Academic Article
• Stationary Phase Expression of a NovelEscherichia coliOuter Membrane Lipoprotein and Its Relationship with Mammalian Apolipoprotein D  Academic Article
• Structural Aspects of the Interaction of peptidyl-glycylleucine-carboxyamide, a Highly Potent Antimicrobial Peptide from Frog Skin, with Lipids  Academic Article
• Structural Characterization of Novel Pseudomonas aeruginosa Type IV Pilins  Academic Article
• Structural Characterization of a Novel Chlamydia pneumoniae Type III Secretion-Associated Protein, Cpn0803  Academic Article
• Structural Insights into the Regulation of Foreign Genes inSalmonellaby the Hha/H-NS Complex  Academic Article
• Structural Properties of the Putative Fusion Peptide of Fertilin, a Protein Active in Sperm−Egg Fusion, upon Interaction with the Lipid Bilayer†  Academic Article
• Structural and Functional Interaction between the Human DNA Repair Proteins DNA Ligase IV and XRCC4  Academic Article
• Structural basis for alginate secretion across the bacterial outer membrane  Academic Article
• Structural biology of membrane-intrinsic β-barrel enzymes: Sentinels of the bacterial outer membrane  Academic Article
• Structural model of a synthetic Ca2+ channel with bound Ca2+ ions and dihydropyridine ligand  Academic Article
• Structural study of the interaction between the mitochondrial presequence of cytochrome c oxidase subunit IV and model membranes.  Academic Article
• Structure and Protein-Protein Interaction Studies on Chlamydia trachomatis Protein CT670 (YscO Homolog)  Academic Article
• Structure of an Asymmetric Ternary Protein Complex Provides Insight for Membrane Interaction  Academic Article
• Structure of an Enzyme Required for Aminoglycoside Antibiotic Resistance Reveals Homology to Eukaryotic Protein Kinases  Academic Article
• Structure of the Cytoplasmic Region of PelD, a Degenerate Diguanylate Cyclase Receptor That Regulates Exopolysaccharide Production inPseudomonas aeruginosa  Academic Article
• Studies of a putative ice-binding motif in winter flounder skin-type anti-freeze polypeptide  Academic Article
• Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson's disease  Academic Article
• Symbiotic nitrogen fixation by a nifA deletion mutant of Rhizobium meliloti: the role of an unusual ntrC allele.  Academic Article
• Synthesis and Dopamine Receptor Modulating Activity of Novel Peptidomimetics ofl-Prolyl-l-leucyl-glycinamide Featuring α,α-Disubstituted Amino Acids  Academic Article
• Synthesis and characterization of a fragment of an ice nucleation protein  Academic Article
• The 1−127 HA2 Construct of Influenza Virus Hemagglutinin Induces Cell−Cell Hemifusion  Academic Article
• The Auto-Inhibitory Role of the EPAC Hinge Helix as Mapped by NMR  Academic Article
• The COOH terminus of aminoglycoside phosphotransferase (3')-IIIa is critical for antibiotic recognition and resistance  Academic Article
• The Pattern of Amino Acid Replacements in α/β-Barrels  Academic Article
• The Polar Region Consecutive to the HIV Fusion Peptide Participates in Membrane Fusion†  Academic Article
• The Projection Analysis of NMR Chemical Shifts Reveals Extended EPAC Autoinhibition Determinants  Academic Article
• The Role of Proline in the Membrane Re-entrant Helix of Caveolin-1  Academic Article
• The Solution Conformational Features of Two Highly Homologous Antigenic Peptides of Foot-and-mouth Disease Virus Serotype A, Variants A and USA, Correlate with their Serological Properties  Academic Article
• The cDNA Sequence of Human Endothelial Cell Multimerin  Academic Article
• The solution structure of Lac repressor headpiece 62 complexed to a symmetrical lac operator  Academic Article
• Type IV Pilin Proteins: Versatile Molecular Modules  Academic Article
• Understanding ribosome assembly: the structure of in vivo assembled immature 30S subunits revealed by cryo-electron microscopy  Academic Article
• Water-macromolecule interactions by NMR: a quadrature-free constant-time approach and its application to CI2.  Academic Article
• Why Does the Inner-Helix Mutation A413C Double the Stoichiometry of Kv1.3 Channel Block by Emopamil but Not by Verapamil?  Academic Article
• YphC and YsxC GTPases assist the maturation of the central protuberance, GTPase associated region and functional core of the 50S ribosomal subunit  Academic Article