Journal article
The Pattern of Amino Acid Replacements in α/β-Barrels
Abstract
The determinants of site-to-site variability in the rate of amino acid replacement in alpha/beta-barrel enzyme structures are investigated. Of 125 available alpha/beta-barrel structures, only 25 meet a variety of phylogenetic and statistical criteria necessary to ensure sufficient data for reliable analysis. These 25 enzyme structures (from a wide variety of taxa with diverse lifestyles in diverse habitats) differ greatly in size, number, and …
Authors
Dean AM; Neuhauser C; Grenier E; Golding GB
Journal
Molecular Biology and Evolution, Vol. 19, No. 11, pp. 1846–1864
Publisher
Oxford University Press (OUP)
Publication Date
November 1, 2002
DOI
10.1093/oxfordjournals.molbev.a004009
ISSN
0737-4038