subject area of
- A Phase I Study of OGX-011, a 2′-Methoxyethyl Phosphorothioate Antisense to Clusterin, in Combination with Docetaxel in Patients with Advanced Cancer Academic Article
- A phase I dose-escalation study of apatorsen (OGX-427), an antisense inhibitor targeting heat shock protein 27 (Hsp27), in patients with castration-resistant prostate cancer and other advanced cancers Conference Paper
- A randomized phase 2 study of a HSP27 targeting antisense, apatorsen with prednisone versus prednisone alone, in patients with metastatic castration resistant prostate cancer Academic Article
- Adenovirus-mediated decorin gene transfer prevents TGF-β-induced inhibition of lung morphogenesis Academic Article
- Antisense Therapy against CCR3 and the Common Beta Chain Attenuates Allergen-induced Eosinophilic Responses Academic Article
- Antisense therapy against CCR3 and the common beta chain attenuates allergen-induced eosinophilic responses Academic Article
- Chemosensitization of gemcitabine-resistant human bladder cancer cell line bothin vitroandin vivousing antisense oligonucleotide targeting the anti-apoptotic gene, clusterin Academic Article
- Clusterin knockdown using the antisense oligonucleotide OGX-011 re-sensitizes docetaxel-refractory prostate cancer PC-3 cells to chemotherapy Academic Article
- Expression of a killer cell receptor-like gene in plastic regions of the central nervous system Academic Article
- Factor XI Antisense Oligonucleotide for Prevention of Venous Thrombosis Academic Article
- Factor XI Antisense Oligonucleotide for Venous Thrombosis Academic Article
- Factor XI and factor XII as targets for new anticoagulants Academic Article
- Immortalized human myotonic dystrophy muscle cell lines to assess therapeutic compounds Academic Article
- Influence of the proto-oncogene c-fos on cisplatin sensitivity Academic Article
- Inhibition of HSP27 blocks fibrosis development and EMT features by promoting Snail degradation Academic Article
- Intravenous Administration of Stabilized Antisense Lipid Particles (SALP) Leads to Activation and Expansion of Liver Natural Killer Cells Academic Article
- Knockdown of spinal metabotropic glutamate receptor 1 (mGluR1) alleviates pain and restores opioid efficacy after nerve injury in rats Academic Article
- Non-canonical Wnt signals are modulated by the Kaiso transcriptional repressor and p120-catenin Academic Article
- Oligonucleotide degradation contributes to resistance to antisense compounds Academic Article
- Phase II Trial of OGX-011 in Combination with Docetaxel in Metastatic Breast Cancer Academic Article
- Phase II multicenter study of oblimersen sodium, a Bcl-2 antisense oligonucleotide, in combination with rituximab in patients with recurrent B-cell non-Hodgkin lymphoma Academic Article
- Reduction in serum clusterin is a potential therapeutic biomarker in patients with castration‐resistant prostate cancer treated with custirsen Academic Article
- Selective depletion of factor XI or factor XII with antisense oligonucleotides attenuates catheter thrombosis in rabbits Academic Article
- Sensory neuron and substance P involvement in symptoms of a zymosan-induced rat model of acute bowel inflammation Academic Article
- Stressproteine bei der Pathogenese des Prostatakarzinoms Academic Article
- TPI ASM8 reduces eosinophil progenitors in sputum after allergen challenge Academic Article
- The pharmacological modulation of allergen-induced asthma Academic Article
- Treatment of lung cancer via telomerase inhibition: Self-assembled nanoplexes versus polymeric nanoparticles as vectors for 2′-O-Methyl-RNA Academic Article
- Urocortin: a mechanism for the sustained activation of the HPA axis in the late-gestation ovine fetus? Academic Article