subject area of
- A Phase I Study of OGX-011, a 2′-Methoxyethyl Phosphorothioate Antisense to Clusterin, in Combination with Docetaxel in Patients with Advanced Cancer Journal Articles
- A phase I dose-escalation study of apatorsen (OGX-427), an antisense inhibitor targeting heat shock protein 27 (Hsp27), in patients with castration-resistant prostate cancer and other advanced cancers Conferences
- A randomized phase 2 study of a HSP27 targeting antisense, apatorsen with prednisone versus prednisone alone, in patients with metastatic castration resistant prostate cancer Journal Articles
- Adenovirus-mediated decorin gene transfer prevents TGF-β-induced inhibition of lung morphogenesis Journal Articles
- Antisense Therapy against CCR3 and the Common Beta Chain Attenuates Allergen-induced Eosinophilic Responses Journal Articles
- Antisense phosphorothioate oligonucleotides: selective killing of the intracellular parasite Leishmania amazonensis. Journal Articles
- Antisense therapy against CCR3 and the common beta chain attenuates allergen-induced eosinophilic responses Journal Articles
- Antisense therapy to block the Kallikrein-kinin pathway in COVID-19: The ASKCOV randomized controlled trial Journal Articles
- Chemosensitization of gemcitabine‐resistant human bladder cancer cell line both in vitro and in vivo using antisense oligonucleotide targeting the anti‐apoptotic gene, clusterin Journal Articles
- Clusterin knockdown using the antisense oligonucleotide OGX‐011 re‐sensitizes docetaxel‐refractory prostate cancer PC‐3 cells to chemotherapy Journal Articles
- Expression of a killer cell receptor-like gene in plastic regions of the central nervous system Journal Articles
- Factor XI Antisense Oligonucleotide for Prevention of Venous Thrombosis Journal Articles
- Factor XI Antisense Oligonucleotide for Venous Thrombosis Journal Articles
- Factor XI Inhibitors: Potential Role in End-Stage Kidney Disease Journal Articles
- Factor XI and factor XII as targets for new anticoagulants Journal Articles
- Immortalized human myotonic dystrophy muscle cell lines to assess therapeutic compounds Journal Articles
- Influence of the proto-oncogene c-fos on cisplatin sensitivity Journal Articles
- Inhibition of HSP27 blocks fibrosis development and EMT features by promoting Snail degradation Journal Articles
- Innovative developments and emerging technologies in RNA therapeutics Journal Articles
- Intravenous Administration of Stabilized Antisense Lipid Particles (SALP) Leads to Activation and Expansion of Liver Natural Killer Cells Journal Articles
- Knockdown of spinal metabotropic glutamate receptor 1 (mGluR1) alleviates pain and restores opioid efficacy after nerve injury in rats Journal Articles
- Making target sites in large structured RNAs accessible to RNA-cleaving DNAzymes through hybridization with synthetic DNA oligonucleotides. Journal Articles
- Non-canonical Wnt signals are modulated by the Kaiso transcriptional repressor and p120-catenin Journal Articles
- Nusinersen versus Sham Control in Later-Onset Spinal Muscular Atrophy Journal Articles
- Oligonucleotide degradation contributes to resistance to antisense compounds Journal Articles
- Phase II Trial of OGX-011 in Combination with Docetaxel in Metastatic Breast Cancer Journal Articles
- Phase II multicenter study of oblimersen sodium, a Bcl‐2 antisense oligonucleotide, in combination with rituximab in patients with recurrent B‐cell non‐Hodgkin lymphoma Journal Articles
- Reduction in serum clusterin is a potential therapeutic biomarker in patients with castration‐resistant prostate cancer treated with custirsen Journal Articles
- Selective depletion of factor XI or factor XII with antisense oligonucleotides attenuates catheter thrombosis in rabbits Journal Articles
- Sensory neuron and substance P involvement in symptoms of a zymosan-induced rat model of acute bowel inflammation Journal Articles
- Stressproteine bei der Pathogenese des Prostatakarzinoms Journal Articles
- TPI ASM8 reduces eosinophil progenitors in sputum after allergen challenge Journal Articles
- Targeting nucleic acid secondary structures by antisense oligonucleotides designed through in vitro selection. Journal Articles
- The pharmacological modulation of allergen-induced asthma Journal Articles
- Treatment of lung cancer via telomerase inhibition: Self-assembled nanoplexes versus polymeric nanoparticles as vectors for 2′-O-Methyl-RNA Journal Articles
- Urocortin: a mechanism for the sustained activation of the HPA axis in the late-gestation ovine fetus? Journal Articles