Interleukin-13 Concept

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A novel ex vivo approach for investigating profibrotic macrophage polarization using murine precision-cut lung slices. Journal Articles
A novel microbe-based treatment that attenuates the inflammatory profile in a mouse model of allergic airway disease Journal Articles
A randomized, placebo‐controlled trial evaluating effects of lebrikizumab on airway eosinophilic inflammation and remodelling in uncontrolled asthma (CLAVIER) Journal Articles
Airway autoimmunity, asthma exacerbations, and response to biologics Journal Articles
Anti-IgE and Biologic Approaches for the Treatment of Asthma Journal Articles
Anti-interleukin-13 and anti-interleukin-4 agents versus placebo, anti-interleukin-5 or anti-immunoglobulin-E agents, for people with asthma Journal Articles
Basophils in airway disease Journal Articles
CD4+ T cell-mediated immunological control of enterochromaffin cell hyperplasia and 5-hydroxytryptamine production in enteric infection Journal Articles
CT and Functional MRI to Evaluate Airway Mucus in Severe Asthma Journal Articles
Cat allergen peptide immunotherapy reduces CD4⁺ T cell responses to cat allergen but does not alter suppression by CD4⁺ CD25⁺ T cells: a double‐blind placebo‐controlled study Journal Articles
Cigarette Smoke Differentially Affects Eosinophilia and Remodeling in a Model of House Dust Mite Asthma Journal Articles
Critical Role for Signal Transducer and Activator of Transcription Factor 6 in Mediating Intestinal Muscle Hypercontractility and Worm Expulsion inTrichinella spiralis-Infected Mice Journal Articles
Cytokines or Their Antagonists for the Treatment of Asthma Journal Articles
Do Complex Conditions Require Complex Treatment? Journal Articles
Dysfunction and Remodeling of the Mouse Airway Persist after Resolution of Acute Allergen-Induced Airway Inflammation Journal Articles
Effects of Interleukin-13 Blockade on Allergen-induced Airway Responses in Mild Atopic Asthma Journal Articles
Eosinophil-derived IL-13 promotes emphysema Journal Articles
Evaluation of Inducible Costimulator/B7-Related Protein-1 as a Therapeutic Target in a Murine Model of Allergic Airway Inflammation Journal Articles
Evaluation of the reproducibility of responses to nasal allergen challenge and effects of inhaled nasal corticosteroids Journal Articles
Expression of functional cysteinyl leukotriene receptors by human basophils Journal Articles
Generation of experimental allergic airways inflammation in the absence of draining lymph nodes Journal Articles
Global Gene Transcriptome Analysis in Vaccinated Cattle Revealed a Dominant Role of IL-22 for Protection against Bovine Tuberculosis Journal Articles
Goblet Cell Rebound and Airway Dysfunction with Corticosteroid Withdrawal in a Mouse Model of Asthma Journal Articles
Granulocyte Macrophage Colony–Stimulating Factor–Driven Respiratory Mucosal Sensitization Induces Th2 Differentiation and Function Independently of Interleukin-4 Journal Articles
Helminth antigen-based strategy to ameliorate inflammation in an experimental model of colitis Journal Articles
IL-12 gene transfer alters gut physiology and host immunity in nematode-infected mice Journal Articles
IL-13-mediated immunological control of enterochromaffin cell hyperplasia and serotonin production in the gut Journal Articles
IL-4 and IL-13 Differentially Regulate TLR-Induced Eosinophil-Basophil Differentiation of Cord Blood CD34+ Progenitor Cells Journal Articles
IL‐13 signature in severe adult asthmatics with airway neutrophilia: A new endotype to treat! Journal Articles
Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia Journal Articles
Induction of interleukin‐10 and suppressor of cytokine signalling‐3 gene expression following peptide immunotherapy Journal Articles
Interleukin 13 and Serotonin: Linking the Immune and Endocrine Systems in Murine Models of Intestinal Inflammation Journal Articles
Interleukin-13–Dependent Expression of Matrix Metalloproteinase-12 Is Required for the Development of Airway Eosinophilia in Mice Journal Articles
Interleukin-4- and -13-induced hypercontractility of human intestinal muscle cells-implication for motility changes in Crohn's disease Journal Articles
Interleukins 4 and 13 Increase Intestinal Epithelial Permeability by a Phosphatidylinositol 3-Kinase Pathway Journal Articles
Interleukin‐4 and interleukin‐13 prime migrational responses of haemopoietic progenitor cells to stromal cell‐derived factor‐1α Journal Articles
Is Interleukin-13 Critical in Maintaining Airway Hyperresposiveness in Allergen-challenged Mice? Journal Articles
Mechanisms Underlying the Maintenance of Muscle Hypercontractility in a Model of Postinfective Gut Dysfunction Journal Articles
Modulation of Human Airway Smooth Muscle Migration by Lipid Mediators and Th-2 Cytokines Journal Articles
Modulation of pulmonary fibrosis by IL-13Rα2 Journal Articles
Modulatory effects of estrogen in two murine models of experimental colitis Journal Articles
Monoclonal antibodies for the treatment of refractory asthma Journal Articles
Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A4 Journal Articles
Oncostatin M (OSM) primes IL-13- and IL-4-induced eotaxin responses in fibroblasts: Regulation of the type-II IL-4 receptor chains IL-4Rα and IL-13Rα1 Journal Articles
Oncostatin M Induction of Monocyte Chemoattractant Protein 1 is Inhibited by Anti-oncostatin M Receptor Beta Monoclonal Antibody KPL-716 Journal Articles
Pulmonary overexpression of IL-10 augments lung fibrosis and Th2 responses induced by silica particles Journal Articles
Role of IL-4, IL-13, and STAT6 in inflammation-induced hypercontractility of murine smooth muscle cells Journal Articles
Role of STAT6 and SMAD2 in a model of chronic allergen exposure: a mouse strain comparison study Journal Articles
STAT-6 Is an Absolute Requirement for Murine Rejection of Hymenolepis diminuta Journal Articles
Secreted PLA2 group X orchestrates innate and adaptive immune responses to inhaled allergen Journal Articles
T helper cell IL-4 drives intestinal Th2 priming to oral peanut antigen, under the control of OX40L and independent of innate-like lymphocytes Journal Articles
TGF-β, Eosinophils and IL-13 in Allergic Airway Remodeling: A Critical Appraisal with Therapeutic Considerations Journal Articles
The interleukin-13 paradox in asthma: effective biology, ineffective biologicals Journal Articles
Thymic stromal lymphopoietin and IL-33 modulate migration of hematopoietic progenitor cells in patients with allergic asthma Journal Articles
Type 2 Cytokines in the Pathogenesis of Sustained Airway Dysfunction and Airway Remodeling in Mice Journal Articles