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Interleukin‐4 and interleukin‐13 prime migrational...
Journal article

Interleukin‐4 and interleukin‐13 prime migrational responses of haemopoietic progenitor cells to stromal cell‐derived factor‐1α

Abstract

BACKGROUND: Lung-homing of progenitor cells is associated with inflammatory and remodelling changes in asthma. Factors that modulate the increased traffic of progenitor cells to the site of inflammation in asthma remain to be defined. Interleukin (IL)-4 and IL-13 are Th2 cytokines that are key regulators of asthma pathology. OBJECTIVE: We investigated the role of IL-4 and IL-13 in modulating the trans-migrational responses of haemopoietic …

Authors

Punia N; Smith S; Thomson JV; Irshad A; Nair P; Sehmi R

Journal

Clinical & Experimental Allergy, Vol. 42, No. 2, pp. 255–264

Publisher

Wiley

Publication Date

February 2012

DOI

10.1111/j.1365-2222.2011.03889.x

ISSN

0954-7894