Inhibitory Concentration 50 Concept

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Activation and Active Site Occupation Alter Conformation in the Region of the First Epidermal Growth Factor-like Domain of Human Factor VII Journal Articles
An ESI‐MS/MS Method for Screening of Small‐Molecule Mixtures against Glycogen Synthase Kinase‐3β (GSK‐3β) Journal Articles
Analysis of Prostaglandin G/H Synthase-2 Inhibition Using Peroxidase-Induced Luminol Luminescence Journal Articles
Antibiotic Susceptibility and Resistance Testing: An Overview Journal Articles
Antimitotic and cell growth inhibitory properties of combretastatin A-4-like ethers Journal Articles
Atypical McMurry Cross-Coupling Reactions Leading to a New Series of Potent Antiproliferative Compounds Bearing the Key [Ferrocenyl-Ene-Phenol] Motif Journal Articles
Calpain inhibitors exhibit matrix metalloproteinase-2 inhibitory activity Journal Articles
Continuous Flow Immobilized Enzyme Reactor–Tandem Mass Spectrometry for Screening of AChE Inhibitors in Complex Mixtures Journal Articles
Designing analogs of ticlopidine, a wall teichoic acid inhibitor, to avoid formation of its oxidative metabolites Journal Articles
Development of New Deoxycytidine Kinase Inhibitors and Noninvasive in Vivo Evaluation Using Positron Emission Tomography Journal Articles
High-Throughput Screening for Human Lysosomal β-N-Acetyl Hexosaminidase Inhibitors Acting as Pharmacological Chaperones Journal Articles
Hypersulfated Low Molecular Weight Heparin with Reduced Affinity for Antithrombin Acts as an Anticoagulant by Inhibiting Intrinsic Tenase and Prothrombinase Journal Articles
Identification of amidoheteroaryls as potent inhibitors of mutant (V600E) B-Raf kinase with in vivo activity Journal Articles
In Vitro Assays for Screening Small Molecules Chapters
Inhibitors of glutamate release from breast cancer cells; new targets for cancer-induced bone-pain Journal Articles
Interactions of doxycycline with chemotherapeutic agents in human breast adenocarcinoma MDA-MB-231 cells Journal Articles
Isolation of DNA Aptamers for CDP‐Ribitol Synthase, and Characterization of Their Inhibitory and Structural Properties Journal Articles
Nanovolume Kinase Inhibition Assay Using a Sol−Gel-Derived Multicomponent Microarray Journal Articles
Naturally occurring resistance of bone marrow mononuclear and metastatic cancer cells to anticancer agents Journal Articles
Real-time fluorogenic kinase assay using protein as substrate Journal Articles
Recombinant albumins containing additional peptide sequences smaller than barbourin retain the ability of barbourin-albumin to inhibit platelet aggregation Journal Articles
STAT3 pathway regulates lung-derived brain metastasis initiating cell capacity through miR-21 activation Journal Articles
Small molecule functional discrimination of the kinases required for the microbial synthesis of threonine and isoleucine Journal Articles
Studies directed towards the refinement of the pancratistatin cytotoxic pharmacophore Journal Articles
Synthesis and Evaluation of Anticancer Natural Product Analogues Based on Angelmarin: Targeting the Tolerance towards Nutrient Deprivation Journal Articles
Synthesis and characterization of cyclohexane-1R,2R-diamine-based Pt(iv) dicarboxylato anticancer prodrugs: their selective activity against human colon cancer cell lines Journal Articles
Synthesis, characterization, structure, molecular modeling studies and biological activity of sterically crowded Pt(II) complexes containing bis(imidazole) ligands Journal Articles
Targeting Prostate-Specific Membrane Antigen (PSMA) with F-18-Labeled Compounds: the Influence of Prosthetic Groups on Tumor Uptake and Clearance Profile Journal Articles
The discovery of rofecoxib, [MK 966, VIOXX®, 4-(4′-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2 inhibitor Journal Articles
pH-Dependent doxorubicin release from terpolymer of starch, polymethacrylic acid and polysorbate 80 nanoparticles for overcoming multi-drug resistance in human breast cancer cells Journal Articles