Hybrid Cells Concept

subject area of

• Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2  Journal Articles
• Analysis of DNA repair in XP–HeLa hybrids; lack of correlation between excision repair of u.v. damage and adenovirus reactivation in an XP(D)-like cell line  Journal Articles
• Camptothecin-resistant mutants of Chinese hamster ovary cells containing a resistant form of topoisomerase I.  Journal Articles
• Chromosome-specific alpha satellite DNA: Isolation and mapping of a polymorphic alphoid repeat from human chromosome 10  Journal Articles
• Clinical features and molecular analysis of the alpha thalassemia/mental retardation syndromes. II. Cases without detectable abnormality of the alpha globin complex.  Journal Articles
• Complementation of arylsulfatase A in somatic hybrids of metachromatic leukodystrophy and multiple sulfatase deficiency disorder fibroblasts.  Journal Articles
• DRB resistance in Chinese hamster and human cells: Genetic and biochemical characteristics of the selection system  Journal Articles
• Diphtheria toxin resistance in chinese hamster cells: Genetic and biochemical characteristics of the mutants affected in protein synthesis  Journal Articles
• Effects of nitric oxide donors on cybrids harbouring the mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) A3243G mitochondrial DNA mutation  Journal Articles
• Evidence for functional hemizygosity at the Emtr locus in CHO cells through segregation analysis  Journal Articles
• Genetic mapping of DNA segments relative to the locus for the fragile-X syndrome at Xq27.3.  Journal Articles
• Human embryonic zeta-globin gene expression in mouse-human hybrid erythroid cell lines  Journal Articles
• Isolation and Mapping of 45 NotI Linking Clones to Chromosome 22  Journal Articles
• Isolation and characterization of an ?-satellite repeated sequence from human chromosome 22  Journal Articles
• Mapping of the human adenylosuccinate lyase (ADSL) gene to chromosome 22q13.1→q13.2  Journal Articles
• Molecular organization and haplotype analysis of centromeric DNA from human chromosome 17: Implications for linkage in neurofibromatosis  Journal Articles
• Mutants of CHO cells resistant to the protein synthesis inhibitor emetine: Genetic and biochemical characterization of second-step mutants  Journal Articles
• Mutants of CHO cells resistant to the protein synthesis inhibitors, cryptopleurine and tylocrebrine: genetic and biochemical evidence for common site of action of emetine, cryptopleurine, tylocrebrine, and tubulosine  Journal Articles
• Non-selective isolation of human somatic cell hybrids by unit-gravity sedimentation  Journal Articles
• Novel mutants of CHO cells resistant to adenosine analogs and containing biochemically altered form of adenosine kinase in cell extracts  Journal Articles
• Organization and genomic distribution of ?82H? alpha satellite DNA  Journal Articles
• Pactamycin resistance in CHO cells: Morphological changes induced by the drug in the wild‐type and mutant cells  Journal Articles
• Physical mapping by FISH of the DiGeorge critical region (DGCR): involvement of the region in familial cases.  Journal Articles
• Production of Human Alpha- and BetaInterferons by Human–Rodent Hybrids  Journal Articles
• Production of hybrid cell lines secreting antibodies to herpes simplex virus type 2  Journal Articles
• Pseudo arylsulfatase-A deficiency in healthy individuals: genetic and biochemical relationship to metachromatic leukodystrophy.  Journal Articles
• Random segregation of multiple genetic markers from CHO-CHO hybrids: Evidence for random distribution of functional hemizygosity in the genome  Journal Articles
• Regional localization of 18 human X-linked DNA sequences  Journal Articles
• Relative tumorigenicities of hybrid cells with and without hsr‐bearing chromosomes from a human melanoma cell line  Journal Articles
• Repopulation of ?0 cells with mitochondria from a patient with a mitochondrial DNA point mutation in tRNAGly results in respiratory chain dysfunction  Journal Articles
• Somatic cell hybridization of Roberts syndrome and normal human fibroblasts transfected with plasmids carrying dominant selection markers  Journal Articles
• Somatic cell hybridization studies on the genetic regulation and allelic mutations in metachromatic leukodystrophy  Journal Articles
• Structure, organization, and sequence of alpha satellite DNA from human chromosome 17: evidence for evolution by unequal crossing-over and an ancestral pentamer repeat shared with the human X chromosome.  Journal Articles
• Studies on temperature-sensitive mutants of Chinese hamster ovary cells affected in DNA synthesis  Journal Articles
• Taxol resistant mutants of Chinese hamster ovary cells: Genetic biochemical, and cross‐resistance studies  Journal Articles
• Telomere elongation in immortal human cells without detectable telomerase activity.  Journal Articles
• The CGL1 (HeLa × Normal Skin Fibroblast) Human Hybrid Cell Line: A History of Ionizing Radiation Induced Effects on Neoplastic Transformation and Novel Future Directions in SNOLAB  Journal Articles
• The human arylsulfatase-C isoenzymes: two distinct genes that escape from X inactivation.  Journal Articles
• The molecular basis of emetine resistance in chinese hamster ovary cells: Alteration in the 40S ribosomal subunit  Journal Articles
• Transcriptomic profiling of gamma ray induced mutants from the CGL1 human hybrid cell system reveals novel insights into the mechanisms of radiation-induced carcinogenesis  Journal Articles
• Xeroderma pigmentosum d-hela hybrids with low and high ultraviolet sensitivity associated with normal and diminished dna repair ability, respectively  Journal Articles
• pG95α1-7dIII/RI, a single copy clone at Xp11.4 which recognises a TaqI polymorphism (DXS209)  Journal Articles