Journal article
Human Embryonic ζ-Globin Gene Expression in Mouse-Human Hybrid Erythroid Cell Lines
Abstract
The human alpha-globin-like embryonic zeta-globin chains are present in abundance during the first 5 to 6 weeks of gestation. Subsequently, zeta-globin chains are present in fetal blood at a very low level, which is supplanted by the expression of alpha-globin chains. Adult individuals who are carriers of the (--SEA/) alpha-thalassemia deletion, in contrast to normal adults, have low levels of embryonic zeta-globin chains in their circulating …
Authors
Luo H-Y; Deisseroth AB; Chui DHK
Journal
Blood, Vol. 86, No. 3, pp. 1212–1217
Publisher
American Society of Hematology
Publication Date
August 1, 1995
DOI
10.1182/blood.v86.3.1212.1212
ISSN
0006-4971