Histone Deacetylase Inhibitors Concept

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• 5-Azacytidine upregulates melatonin MT1 receptor expression in rat C6 glioma cells: oncostatic implications  Journal Articles
• A phase I trial of two sequence-specific schedules of decitabine and vorinostat in patients with acute myeloid leukemia  Journal Articles
• A phase II study of SB939, a novel pan-histone deacetylase inhibitor, in patients with translocation-associated recurrent/metastatic sarcomas—NCIC-CTG IND 200  Journal Articles
• An Endogenous Reactive Oxygen Species (ROS)‐Activated Histone Deacetylase Inhibitor Prodrug for Cancer Chemotherapy  Journal Articles
• Behavioral and neurochemical effects of sodium butyrate in an animal model of mania  Journal Articles
• Clinically relevant concentrations of valproic acid modulate melatonin MT1 receptor, HDAC and MeCP2 mRNA expression in C6 glioma cells  Journal Articles
• Compensatory regulation of HDAC5 in muscle maintains metabolic adaptive responses and metabolism in response to energetic stress  Journal Articles
• Discovery of HDAC6-Selective Inhibitor NN-390 with in Vitro Efficacy in Group 3 Medulloblastoma  Journal Articles
• Effects of sodium butyrate on aversive memory in rats submitted to sepsis  Journal Articles
• HDAC Inhibition Suppresses Primary Immune Responses, Enhances Secondary Immune Responses, and Abrogates Autoimmunity During Tumor Immunotherapy  Journal Articles
• HDAC inhibitor M344 suppresses MCF-7 breast cancer cell proliferation  Journal Articles
• HDACi Delivery Reprograms Tumor-Infiltrating Myeloid Cells to Eliminate Antigen-Loss Variants  Journal Articles
• HDACi promotes inflammatory remodeling of the tumor microenvironment to enhance epitope spreading and antitumor immunity  Journal Articles
• Histone Deacetylation Is Involved in the Transcriptional Repression of hTERT in Normal Human Cells  Journal Articles
• Histone deacetylase inhibitors suppress ACE2 and ABO simultaneously, suggesting a preventive potential against COVID-19  Journal Articles
• Identification and Characterization of AES-135, a Hydroxamic Acid-Based HDAC Inhibitor That Prolongs Survival in an Orthotopic Mouse Model of Pancreatic Cancer  Journal Articles
• Induction of GRP78 by valproic acid is dependent upon histone deacetylase inhibition  Journal Articles
• Induction of Neurotrophic and Differentiation Factors in Neural Stem Cells by Valproic Acid  Journal Articles
• Inhibition of histone deacetylation with vorinostat does not prevent tunicamycin-mediated acute kidney injury  Journal Articles
• Neuroanatomical Profile of Antimaniac Effects of Histone Deacetylases Inhibitors  Journal Articles
• Novel Treatments for Multiple Myeloma: What Role Do They Have in Older Adults?  Journal Articles
• Phase I clinical, pharmacokinetic and pharmacodynamic study of SB939, an oral histone deacetylase (HDAC) inhibitor, in patients with advanced solid tumours  Journal Articles
• Phase I/II study of the deacetylase inhibitor panobinostat after allogeneic stem cell transplantation in patients with high-risk MDS or AML (PANOBEST trial)  Journal Articles
• Phase II trial of the histone deacetylase inhibitor belinostat in women with platinum resistant epithelial ovarian cancer and micropapillary (LMP) ovarian tumours  Journal Articles
• Phase II trial of vorinostat in advanced melanoma  Journal Articles
• Reversal of p15/INK4b hypermethylation in AML1/ETO-positive and -negative myeloid leukemia cell lines  Journal Articles
• Scriptaid enhances skeletal muscle insulin action and cardiac function in obese mice  Journal Articles
• The HDAC class I-specific inhibitor entinostat (MS-275) effectively relieves epigenetic silencing of the LAT2 gene mediated by AML1/ETO  Journal Articles
• The histone deacetylase inhibitor valproic acid alters sensitivity towards all trans retinoic acid in acute myeloblastic leukemia cells  Journal Articles
• Therapeutic fetal-globin inducers reduce transcriptional repression in hemoglobinopathy erythroid progenitors through distinct mechanisms  Journal Articles