Journal article
Histone deacetylase inhibitors suppress ACE2 and ABO simultaneously, suggesting a preventive potential against COVID-19
Abstract
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide as a pandemic throughout 2020. Since the virus uses angiotensin-converting enzyme 2 (ACE2) as a receptor for cellular entry, increment of ACE2 would lead to an increased risk of SARS-CoV-2 infection. At the same time, an association of the ABO blood group system with COVID-19 has also been highlighted: there is …
Authors
Takahashi Y; Hayakawa A; Sano R; Fukuda H; Harada M; Kubo R; Okawa T; Kominato Y
Journal
Scientific Reports, Vol. 11, No. 1,
Publisher
Springer Nature
DOI
10.1038/s41598-021-82970-2
ISSN
2045-2322