bcl-2-Associated X Protein Concept

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Escherichia coliShiga toxins induce apoptosis in epithelial cells that is regulated by the Bcl-2 family Journal Articles
A Small-Molecule Inhibitor of Bax and Bak Oligomerization Prevents Genotoxic Cell Death and Promotes Neuroprotection Journal Articles
Allosteric Regulation of BH3 Proteins in Bcl-xL Complexes Enables Switch-like Activation of Bax Journal Articles
Alterations in Mitochondrial and Apoptosis‐regulating Gene Expression in Photodynamic Therapy‐resistant Variants of HT29 Colon Carcinoma Cells^¶ Journal Articles
Apoptosis and other effects of radiation in normal human urothelial cells Journal Articles
Apoptosis induction by eIF5A1 involves activation of the intrinsic mitochondrial pathway Journal Articles
Apoptosis: embedded in membranes Journal Articles
BCL-2: the pendulum of the cell fate. Journal Articles
BMS-214662 induces mitochondrial apoptosis in chronic myeloid leukemia (CML) stem/progenitor cells, including CD34+38− cells, through activation of protein kinase Cβ Journal Articles
Bax Forms an Oligomer via Separate, Yet Interdependent, Surfaces Journal Articles
Bax Homodimerization Is Not Required for Bax to Accelerate Chemotherapy-induced Cell Death Journal Articles
Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis Journal Articles
Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator Journal Articles
Bcl-2 changes conformation to inhibit Bax oligomerization Journal Articles
Bcl-2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types. Journal Articles
Bcl-XL Inhibits Membrane Permeabilization by Competing with Bax Journal Articles
Characterization of a new cancer-associated mutant of p53 with a missense mutation (K351N) in the tetramerization domain Journal Articles
Direct Measurement of the Affinity between tBid and Bax in a Mitochondria-Like Membrane Journal Articles
Distinct lipid effects on tBid and Bim activation of membrane permeabilization by pro-apoptotic Bax Journal Articles
Early Dexamethasone Treatment Induces Placental Apoptosis in Sheep Journal Articles
Effect of docetaxel (taxotere) on expression of radiation-induced lethal mutations in human cell lines Journal Articles
Embedded together: The life and death consequences of interaction of the Bcl-2 family with membranes Journal Articles
Endoplasmic reticulum localized Bcl-2 prevents apoptosis when redistribution of cytochrome c is a late event Journal Articles
Endoplasmic reticulum protein BIK binds to and inhibits mitochondria-localized antiapoptotic proteins Journal Articles
Examining the Molecular Mechanism of Bcl-2 Family Proteins at Membranes by Fluorescence Spectroscopy Journal Articles
Expression of apoptosis-related proteins in thyroid tumors and thyroid carcinoma cell lines Journal Articles
Expression of delayed toxicity and lethal mutations in the progeny of human cells surviving exposure to radiation and other environmental mutagens Conferences
Expression of survivin and p16INK4a/Cdk6/pRB proteins and induction of apoptosis in response to radiation and cisplatin in meningioma cells Journal Articles
Gross thymic extract, Thymax, induces apoptosis in human breast cancer cells in vitro through the mitochondrial pathway. Conferences
Gut Mucosal Homeostasis and Cellular Mediators after Severe Thermal Trauma and the Effect of Insulin-Like Growth Factor-I in Combination with Insulin-Like Growth Factor Binding Protein-3 Journal Articles
HDAC inhibitor M344 suppresses MCF-7 breast cancer cell proliferation Journal Articles
Identification of single‐domain, Bax‐specific intrabodies that confer resistance to mammalian cells against oxidative‐stress‐induced apoptosis Journal Articles
Immunohistochemical analysis of Bcl-2, Bcl-X, Mcl-1, and Bax in tumors of central and peripheral nervous system origin. Journal Articles
Induction of Mdm2 and enhancement of cell survival by bFGF Journal Articles
Interaction of the full-length Bax protein with biomimetic mitochondrial liposomes: A small-angle neutron scattering and fluorescence study Journal Articles
Interaction with a Membrane Surface Triggers a Reversible Conformational Change in Bax Normally Associated with Induction of Apoptosis Journal Articles
Manganese Superoxide Dismutase Levels Are Elevated in a Proportion of Amyotrophic Lateral Sclerosis Patient Cell Lines Journal Articles
Membrane Binding by tBid Initiates an Ordered Series of Events Culminating in Membrane Permeabilization by Bax Journal Articles
Mitochondrial dysfunction is associated with a pro-apoptotic cellular environment in senescent cardiac muscle Journal Articles
Multiple partners can kiss-and-run: Bax transfers between multiple membranes and permeabilizes those primed by tBid Journal Articles
Myc Potentiates Apoptosis by Stimulating Bax Activity at the Mitochondria Journal Articles
Pancratistatin Selectively Targets Cancer Cell Mitochondria and Reduces Growth of Human Colon Tumor Xenografts Journal Articles
Persistent DNA damage induced by ultraviolet light inhibits p21waf1 and bax expression: implications for DNA repair, UV sensitivity and the induction of apoptosis Journal Articles
Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance Journal Articles
Regulation of Acidification and Apoptosis by SHP-1 and Bcl-2 Journal Articles
SBDS-deficient cells undergo accelerated apoptosis through the Fas-pathway Journal Articles
Small molecules reveal an alternative mechanism of Bax activation Journal Articles
Survival of human epithelial cells irradiated with cobalt 60 as microcolonies or single cells Journal Articles
The Cancer-associated K351N Mutation Affects the Ubiquitination and the Translocation to Mitochondria of p53 Protein Journal Articles
The carboxyl-terminal sequence of bim enables bax activation and killing of unprimed cells Journal Articles
The cigarette smoke constituent benzo[a]pyrene disrupts metabolic enzyme, and apoptosis pathway member gene expression in ovarian follicles Journal Articles
The effect of hepatocyte growth factor on gut mucosal apoptosis and proliferation, and cellular mediators after severe trauma Journal Articles
Water-soluble formulation of Coenzyme Q10 inhibits Bax-induced destabilization of mitochondria in mammalian cells Journal Articles
p14ARF inhibits the growth of p53 deficient cells in a cell-specific manner Journal Articles
tBid Undergoes Multiple Conformational Changes at the Membrane Required for Bax Activation Journal Articles