Anti-Asthmatic Agents Concept

subject area of

• OX40L blockade and allergen‐induced airway responses in subjects with mild asthma  Journal Articles
• A Nonsteroidal Glucocorticoid Receptor Agonist Inhibits Allergen-induced Late Asthmatic Responses  Journal Articles
• A call to action for improving clinical outcomes in patients with asthma  Journal Articles
• A case series of dual biologics therapy for severe asthma  Journal Articles
• A halotyrosine antibody that detects increased protein modifications in asthma patients  Journal Articles
• A new perspective on concepts of asthma severity and control  Journal Articles
• A patient decision aid for mild asthma: Navigating a new asthma treatment paradigm  Journal Articles
• A pragmatic single-blind randomised controlled trial and economic evaluation of the use of leukotriene receptor antagonists in primary care at steps 2 and 3 of the national asthma guidelines (ELEVATE study).  Journal Articles
• A randomized, placebo‐controlled trial evaluating effects of lebrikizumab on airway eosinophilic inflammation and remodelling in uncontrolled asthma (CLAVIER)  Journal Articles
• A summary of the new GINA strategy: a roadmap to asthma control  Journal Articles
• A systematic review of adverse drug events associated with administration of common asthma medications in children  Journal Articles
• Adding formoterol to budesonide in moderate asthma—health economic results from the FACET study  Journal Articles
• Aerosols and devices  Journal Articles
• Age trends in direct medical costs of pediatric asthma: A population study  Journal Articles
• Airway autoimmunity, asthma exacerbations, and response to biologics  Journal Articles
• Airway smooth muscle as a target of asthma therapy: history and new directions  Journal Articles
• Anti-alarmin asthma therapies: where do we go from here?  Journal Articles
• Anti-interleukin-13 and anti-interleukin-4 agents versus placebo, anti-interleukin-5 or anti-immunoglobulin-E agents, for people with asthma  Journal Articles
• Antileukotrienes, asthma pathogenesis and the pharmaceutical industry.  Journal Articles
• Anti–Interleukin-5 Monoclonal Antibody to Treat Severe Eosinophilic Asthma  Journal Articles
• Are New Asthma Therapies Needed?  Journal Articles
• Association between parental perception of children's vulnerability to illness and management of children's asthma  Journal Articles
• Asthma Control, Airway Mucus, and 129Xe MRI Ventilation After a Single Benralizumab Dose  Journal Articles
• Asthma and Exercise-Induced Bronchoconstriction in Athletes  Journal Articles
• Asthma control in Canada: no improvement since we last looked in 1999.  Journal Articles
• Asthma exacerbations on benralizumab are largely non‐eosinophilic  Journal Articles
• Asthma exacerbations {middle dot} 1: Epidemiology  Journal Articles
• Asthma maintenance and reliever therapy  Journal Articles
• Asthma maintenance and reliever therapy  Journal Articles
• Asthma progression and mortality: the role of inhaled corticosteroids  Journal Articles
• Asthma therapy: how far have we come, why did we fail and where should we go next?  Journal Articles
• Asthma treatment: antileukotriene drugs.  Journal Articles
• Asthma: management of severe disease  Journal Articles
• Attenuation of the September Epidemic of Asthma Exacerbations in Children: A Randomized, Controlled Trial of Montelukast Added to Usual Therapy  Journal Articles
• Benralizumab Normalizes Sputum Eosinophilia in Severe Asthma Uncontrolled by Anti–IL-5 Antibodies: A Single-Blind, Placebo-controlled Clinical Trial  Journal Articles
• Benralizumab for Prednisone-Dependent Eosinophilic Asthma Associated With Novel STAT3 Loss of Function Mutation  Journal Articles
• Benralizumab for allergic asthma: a randomised, double-blind, placebo-controlled, trial  Journal Articles
• Benralizumab in severe eosinophilic asthma by previous biologic use and key clinical subgroups: real-world XALOC-1 programme  Journal Articles
• Benralizumab, an anti-interleukin-5 receptor α monoclonal antibody, as add-on treatment for patients with severe, uncontrolled, eosinophilic asthma (CALIMA): a randomised, double-blind, placebo-controlled phase 3 trial  Journal Articles
• Blood or sputum eosinophils to guide asthma therapy?  Journal Articles
• Bronchial Thermoplasty for Asthma  Journal Articles
• Changing Paradigms in the Treatment of Severe Asthma: The Role of Biologic Therapies  Journal Articles
• Clinical Comparisons of Inhaler Systems: What are the Important Aspects?  Journal Articles
• Clinical Models to Compare the Safety and Efficacy of Inhaled Corticosteroids in Patients with Asthma  Journal Articles
• Clinical applications of assessment of airway inflammation using induced sputum  Journal Articles
• Clinically Important Improvements in Asthma-Specific Quality of Life, But No Difference in Conventional Clinical Indexes in Patients Changed From Conventional Beclomethasone Dipropionate to Approximately Half the Dose of Extrafine Beclomethasone Dipropionate  Journal Articles
• Combined Analysis of Asthma Safety Trials of Long-Acting β₂-Agonists  Journal Articles
• Combining LABA and ICS in patients with severe COPD  Journal Articles
• Comparison of reported prevalences of recent asthma in longitudinal and cross-sectional studies  Journal Articles
• Comparison of the Effect of Low-Dose Ciclesonide and Fixed-Dose Fluticasone Propionate and Salmeterol Combination on Long-term Asthma Control  Journal Articles
• Computational fluid dynamics model predictions of inhaled corticosteroid deposition in patients with severe asthma.  Journal Articles
• Cytokines or Their Antagonists for the Treatment of Asthma  Journal Articles
• Determinants of cost-effectiveness results of biological therapies for severe asthma: a systematic methodological assessment.  Journal Articles
• Development and validation of a novel risk score for asthma exacerbations: The risk score for exacerbations  Journal Articles
• Device Selection and Outcomes of Aerosol Therapy: Evidence-Based Guidelines  Journal Articles
• Direct and indirect bronchoprovocation tests in dose‐response studies of inhaled corticosteroids: Past, present, and future directions  Journal Articles
• Disease-modifying anti-asthmatic drugs  Journal Articles
• Does early intervention with inhaled corticosteroids alter the natural history of mild persistent asthma?  Journal Articles
• Does the current stepwise approach to asthma pharmacotherapy encourage over‐treatment?  Journal Articles
• Dose-response effects of TPI ASM8 in asthmatics after allergen  Journal Articles
• Early intervention of recent onset mild persistent asthma in children aged under 11 yrs: the Steroid Treatment As Regular Therapy in early asthma (START) trial  Journal Articles
• Early intervention with budesonide in mild persistent asthma: a randomised, double-blind trial  Journal Articles
• Effect of anti‐IL‐5 biologics on weight and body mass index  Journal Articles
• Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia  Journal Articles
• Effects of furosemide on allergic asthmatic responses in mice  Journal Articles
• Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma  Journal Articles
• Efficacy and safety of a CXCR2 antagonist, AZD5069, in patients with uncontrolled persistent asthma: a randomised, double-blind, placebo-controlled trial  Journal Articles
• Efficacy and safety of reslizumab in patients with moderate to severe eosinophilic asthma  Journal Articles
• Efficacy and safety of tralokinumab in patients with severe uncontrolled asthma: a randomised, double-blind, placebo-controlled, phase 2b trial  Journal Articles
• Efficacy and safety of treatment with biologicals (benralizumab, dupilumab and omalizumab) for severe allergic asthma: A systematic review for the EAACI Guidelines ‐ recommendations on the use of biologicals in severe asthma  Journal Articles
• Efficacy and safety of treatment with biologicals (benralizumab, dupilumab, mepolizumab, omalizumab and reslizumab) for severe eosinophilic asthma. A systematic review for the EAACI Guidelines ‐ recommendations on the use of biologicals in severe asthma  Journal Articles
• Efficacy and safety of treatment with dupilumab for severe asthma: A systematic review of the EAACI guidelines—Recommendations on the use of biologicals in severe asthma  Journal Articles
• Efficacy of Intravenous Reslizumab in Oral Corticosteroid–Dependent Asthma  Journal Articles
• Efficacy of budesonide/formoterol maintenance and reliever therapy compared with higher-dose budesonide as step-up from low-dose inhaled corticosteroid treatment  Journal Articles
• Efficacy of leukotriene receptor antagonists and synthesis inhibitors in asthma  Journal Articles
• Emerging airway smooth muscle targets to treat asthma  Journal Articles
• Endotypes of difficult-to-control asthma in inner-city African American children  Journal Articles
• Eosinophilic Endotype of Asthma  Journal Articles
• Evaluation of Asthma Control by Physicians and Patients: Comparison with Current Guidelines  Journal Articles
• Exacerbations of Severe Asthma While on Anti–IL-5 Biologics  Journal Articles
• From Bench to Bedside  Journal Articles
• GM-CSF and Dendritic Cells in Allergic Airway Inflammation: Basic Mechanisms and Prospects for Therapeutic Intervention  Journal Articles
• Global Quality Statements on Reliever Use in Asthma in Adults and Children Older than 5 Years of Age  Journal Articles
• Global guidelines for asthma management. Summary of the current status and future challenges  Journal Articles
• Global strategy for asthma management and prevention: GINA executive summary  Journal Articles
• Glucocorticoid Sparing of Benralizumab in Asthma  Journal Articles
• Guidelines for the emergency management of asthma in adults. CAEP/CTS Asthma Advisory Committee. Canadian Association of Emergency Physicians and the Canadian Thoracic Society.  Journal Articles
• How much is too much? The treatment of mild asthma  Journal Articles
• Identifying ‘well-controlled’ and ‘not well-controlled’ asthma using the Asthma Control Questionnaire  Journal Articles
• Implementing Continuing Education Strategies for Family Physicians to Enhance Asthma Patients' Quality of Life  Journal Articles
• Inhaled Corticosteroid Therapy in Newly Detected Mild Asthma  Journal Articles
• Inhaled Reliever Therapies for Asthma: A Systematic Review and Meta-Analysis.  Journal Articles
• Integrated safety and efficacy analysis of once-daily fluticasone furoate for the treatment of asthma  Journal Articles
• Is Asthma a Risk Factor for Dental Caries? Findings from a Cohort Study  Journal Articles
• Is it safe to use long‑acting β‑agonists in asthma and chronic obstructive pulmonary disease? Implications of recent trials and meta‑analyses  Journal Articles
• Is tezepelumab more than just an anti-eosinophil drug?  Journal Articles
• Is there a place for anti-remodelling drugs in asthma which may not display immediate clinical efficacy?  Journal Articles
• Leukotriene Antagonists as First-Line or Add-on Asthma-Controller Therapy  Journal Articles
• Leukotriene Antagonists in Asthma  Journal Articles
• Levalbuterol has not been established to have therapeutic advantage over racemic albuterol  Journal Articles
• Long-Acting β₂-Agonist Step-off in Patients With Controlled Asthma  Journal Articles
• Long-acting β-Agonists, Tachyphylaxis, and Corticosteroids  Journal Articles
• Long-term safety and efficacy of benralizumab in patients with severe, uncontrolled asthma: 1-year results from the BORA phase 3 extension trial  Journal Articles
• Maintenance of asthma control by once‐daily inhaled ciclesonide in adults with persistent asthma  Journal Articles
• Management of asthma exacerbation in adults – guidelines for primary care doctors  Journal Articles
• Management of asthma in adults  Journal Articles
• Management of chronic asthma in adults in diverse regions of the world.  Journal Articles
• Measurement characteristics of two asthma symptom diary scales for use in clinical trials  Journal Articles
• Measurement properties and interpretation of three shortened versions of the asthma control questionnaire  Journal Articles
• Measuring Asthma Control  Journal Articles
• Measuring Total and Regional Lung Deposition Using Inhaled Radiotracers  Journal Articles
• Mechanisms and treatments for severe, steroid‐resistant allergic airway disease and asthma  Journal Articles
• Medical algorithms: Approach to adult asthma exacerbations  Journal Articles
• Medication compliance and disease exacerbation in patients with asthma: a retrospective study of managed care data  Journal Articles
• Metered‐dose inhaler ipratropium bromide in moderate acute asthma in children: A single‐blinded randomised controlled trial  Journal Articles
• Methacholine test and the diagnosis of asthma  Journal Articles
• Monitoring eosinophils to guide therapy with biologics in asthma: does the compartment matter?  Journal Articles
• Monoclonal antibodies for the treatment of refractory asthma  Journal Articles
• Montelukast Treatment Attenuates the Increase in Myofibroblasts Following Low-Dose Allergen Challenge  Journal Articles
• Montelukast as Add-On Therapy with Inhaled Corticosteroids Alone or Inhaled Corticosteroids and Long-Acting Beta-2-Agonists in the Management of Patients Diagnosed with Asthma and Concurrent Allergic Rhinitis (the RADAR Trial)  Journal Articles
• Montelukast as Add‐On Therapy to Inhaled Corticosteroids in the Management of Asthma (The SAS Trial)  Journal Articles
• Montelukast as an Alternative to Low‐Dose Inhaled Corticosteroids in the Management of Mild Asthma (The SIMPLE Trial): An Open‐Label Effectiveness Trial  Journal Articles
• Montelukast in childhood asthma: what is the evidence for its use?  Journal Articles
• New Delivery Systems and Propellants  Journal Articles
• New paradigm in asthma management: Switching between biologics!  Journal Articles
• New treatment approaches for asthma  Journal Articles
• Normalisation of MRI ventilation heterogeneity in severe asthma by dupilumab  Journal Articles
• Novel therapy for asthma  Journal Articles
• Omalizumab for asthma in adults and children  Journal Articles
• Once-daily ciclesonide 80 or 320μg for 12 weeks is safe and effective in patients with persistent asthma  Journal Articles
• Once-daily fluticasone furoate (FF)/vilanterol reduces risk of severe exacerbations in asthma versus FF alone  Journal Articles
• Once-daily fluticasone furoate alone or combined with vilanterol in persistent asthma  Journal Articles
• Once‐daily fluticasone furoate 50 mcg in mild‐to‐moderate asthma: a 24‐week placebo‐controlled randomized trial  Journal Articles
• Oral Glucocorticoid–Sparing Effect of Benralizumab in Severe Asthma  Journal Articles
• Overall asthma control: The relationship between current control and future risk  Journal Articles
• Patient-centred composite scores as tools for assessment of response to biological therapy for paediatric and adult severe asthma.  Journal Articles
• Pharmacoeconomics in Pediatric Asthma  Journal Articles
• Pharmacologic Interventions to Reduce the Risk of Asthma Exacerbations  Journal Articles
• Pharmacologic modulation of airway inflammation  Conferences
• Pharmacotherapeutic management of asthma in pregnancy and the effect of sex hormones  Journal Articles
• Positioning As-needed Budesonide–Formoterol for Mild Asthma: Effect of Prestudy Treatment in Pooled Analysis of SYGMA 1 and 2  Journal Articles
• Potential Masking Effects of Salmeterol on Airway Inflammation in Asthma  Journal Articles
• Pranlukast, a cysteinyl leukotriene receptor antagonist, attenuates allergen-induced early- and late-phase bronchoconstriction and airway hyperresponsiveness in asthmatic subjects  Journal Articles
• Prolonged bronchoprotection against inhaled methacholine by inhaled BI 1744, a long-acting β2-agonist, in patients with mild asthma  Journal Articles
• Prolonged protection against exercise-induced bronchoconstriction by the leukotriene D4–receptor antagonist cinalukast☆☆☆★  Journal Articles
• Pulmonary function testing in the Emergency Department and medications prescribed at discharge: results of the Multinational Acute asthma Management, Burden, and Outcomes (MAMBO) study  Journal Articles
• Quality of life questionnaires: Does statistically significant = clinically important?  Journal Articles
• Real-Life Outcomes for Patients with Asthma Prescribed Spacers for Use with Either Extrafine- or Fine-Particle Inhaled Corticosteroids  Journal Articles
• Real-world health care utilization and effectiveness of omalizumab for the treatment of severe asthma  Journal Articles
• Recent Advances in the Pathophysiology of Asthma  Journal Articles
• Reevaluation of Diagnosis in Adults With Physician-Diagnosed Asthma  Journal Articles
• Regular treatment with formoterol and inhaled steroids for chronic asthma: serious adverse events  Journal Articles
• Regular treatment with formoterol and inhaled steroids for chronic asthma: serious adverse events  Journal Articles
• Regular treatment with salmeterol and inhaled steroids for chronic asthma: serious adverse events  Journal Articles
• Regular treatment with salmeterol and inhaled steroids for chronic asthma: serious adverse events  Journal Articles
• Relationship between quality of life and clinical status in asthma: a factor analysis  Journal Articles
• Reply to Yilmaz: Selection of Biologics for Type 2–High Asthma  Journal Articles
• Response of sputum periostin to anti‐T2 biologics treatment in severe asthma  Journal Articles
• Risankizumab in Severe Asthma — A Phase 2a, Placebo-Controlled Trial  Journal Articles
• Risk of congenital malformations associated with treatment of asthma during early pregnancy  Journal Articles
• Risk of new onset diabetes mellitus in patients with asthma or COPD taking inhaled corticosteroids  Journal Articles
• Role of Biologics in Asthma  Journal Articles
• Role of Leukotrienes and Leukotriene Receptor Antagonists in Asthma  Journal Articles
• Role of Thymic Stromal Lymphopoietin in the Pathophysiology of Asthma and Clinical and Biological Effects of Blockade With Tezepelumab  Journal Articles
• Role of local eosinophilopoietic processes in the development of airway eosinophilia in prednisone‐dependent severe asthma  Journal Articles
• Sample sizes for clinical trials using sputum eosinophils as a primary outcome  Journal Articles
• Severe asthma: future treatments  Journal Articles
• Significant variability in response to inhaled corticosteroids for persistent asthma  Journal Articles
• Single-dose desloratadine and montelukast and allergen-induced late airway responses  Journal Articles
• Sputum Hyaluronan and Versican in Severe Eosinophilic Asthma  Journal Articles
• Sputum autoantibodies in patients with severe eosinophilic asthma  Journal Articles
• Sputum cytokines associated with raised FeNO after anti‐IL5 biologic therapy in severe asthma  Journal Articles
• Suboptimal treatment response to anti-IL-5 monoclonal antibodies in severe eosinophilic asthmatics with airway autoimmune phenomena  Journal Articles
• TNF‐α Dysregulation in Asthma: Relationship to Ongoing Corticosteroid Therapy  Journal Articles
• Tezepelumab in patients with allergic and eosinophilic asthma  Journal Articles
• The GINA asthma strategy report: what’s new for primary care?  Journal Articles
• The Global Initiative for Asthma (GINA): 25 years later  Journal Articles
• The Placebo Effect in Asthma Drug Therapy Trials: A Meta-Analysis  Journal Articles
• The Role of Omalizumab in the Treatment of Severe Allergic Asthma  Journal Articles
• The September epidemic of asthma exacerbations in children: A search for etiology  Journal Articles
• The effect of montelukast, budesonide alone, and in combination on exercise-induced bronchoconstriction  Journal Articles
• The effects of a CCR3 inhibitor, AXP1275, on allergen‐induced airway responses in adults with mild‐to‐moderate atopic asthma  Conferences
• The management of mild asthma  Journal Articles
• The safety of long‐acting beta‐agonists: More evidence is needed  Journal Articles
• The use of sputum cell counts to evaluate asthma medications  Journal Articles
• The utility of methacholine airway responsiveness measurements in evaluating anti-asthma drugs☆☆☆★★★  Journal Articles
• Therapeutic implications of ‘neutrophilic asthma’  Journal Articles
• Therapeutic strategies to reduce asthma exacerbations  Journal Articles
• Thymic stromal lymphopoietin: its role and potential as a therapeutic target in asthma  Journal Articles
• Timing is everything: Targeting IgE to reduce asthma exacerbation risk  Journal Articles
• Tiotropium for the treatment of asthma: a drug safety evaluation  Journal Articles
• Treatment of Asthma with Drugs Modifying the Leukotriene Pathway  Journal Articles
• Treatment of mild asthma  Journal Articles
• Triple vs Dual Inhaler Therapy and Asthma Outcomes in Moderate to Severe Asthma  Journal Articles
• Understanding the September asthma epidemic  Journal Articles
• Usage Patterns of Short-Acting β2-Agonists and Inhaled Corticosteroids in Asthma: A Targeted Literature Review  Journal Articles
• Use of Asthma Medication During Gestation and Risk of Specific Congenital Anomalies  Journal Articles
• Use of peak expiratory flow meters in adults: practical aspects.  Journal Articles
• Variations and Gaps in Management of Acute Asthma in Ontario Emergency Departments  Journal Articles
• What Is New Since the Last (1999) Canadian Asthma Consensus Guidelines?  Journal Articles
• What have we learnt about asthma control from trials of budesonide/formoterol as maintenance and reliever?  Journal Articles