selected scholarly activity
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chapters
- Thrombophilia and Hormonal Therapy in Adolescents. 163-174. 2020
- Anticoagulation in pregnancy. 197-219. 2016
- Thrombophilia in Pregnancy. 627-647. 2013
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conferences
- Planning the APPLE (AntiPhosPholipid syndrome Low-molecular-weight heparin pregnancy loss Evaluation) clinical trial: an international survey of physicians. Thrombosis Research. S122-S122. 2017
- Pilot Study of Online Learning Modules for Hemoglobinopathy Education in Canadian Hematology Training Programs. Blood. 314-314. 2016
- Low Molecular Weight Heparin for Prevention of Placenta-Mediated Pregnancy Complications: An Individual Patient Data Meta-Analysis. Blood. 2015
- women’s Values and Preferences: Decision Making about Thromboprophylaxis in Pregnancy: 445.. Pharmacoepidemiology and Drug Safety. 252-253. 2015
- Hemoglobinopathy Education in Canadian Hematology Training Programs: How Much Are Residents Learning?. Blood. 2168-2168. 2014
- Making Decisions about Thromboprophylaxis in Pregnancy: Women’s Values and Preferences. Blood. 2014
- Combination Of 4T’s Score and Rapid Gel Centrifugation Assay Excludes HIT In a Prospective Cohort Study. Blood. 3535-3535. 2013
- Development and accreditation of a standardized training program in thrombosis and vascular medicine - a Canadian initiative. Journal of Thrombosis and Haemostasis. 602-602. 2013
- Performance of fibrin monomer in the evaluation of patients with suspected pulmonary embolism. Journal of Thrombosis and Haemostasis. 733-733. 2013
- Positive Predictive Value of Progressively Elevated D-Dimer Levels in Patients with a Suspected First Deep Vein Thrombosis.. Blood. 2258-2258. 2012
- Safe exclusion of deep vein thrombosis in primary and secondary care using the wells-rule; a large individual patient data meta-analysis. European Heart Journal. 551-551. 2011
- Age-adjusted D-dimer cut-off value increases the number of older patients in whom deep vein thrombosis can be safely excluded. Journal of Thrombosis and Haemostasis. 305-305. 2011
- Safe exclusion of deep vein thrombosis in primary and secondary care using the wells-rule; a large individual patient data meta-analysis. Journal of Thrombosis and Haemostasis. 751-751. 2011
- North American and British guidelines for anti-thrombotic therapy: are we reaching consensus?. Thrombosis Research. S111-S123. 2009
- A negative D-dimer excludes recurrent deep vein thrombosis: Results of a multicentre management study.. Blood. 215A-215A. 2007
- DOPPLER COMPRESSION ULTRASOUND OF THE LOWER EXTREMITIES IN ICU PATIENTS: AN INTER-RATER RELIABILITY STUDY. Critical Care Medicine. A77-A77. 2002
- Prospective Multicentre trial of bridging therapy with dalteparin for patients who require temporary discontinuation of OAC for prosthetic valves or high risk atrial fibrillation.. Blood. 149A-149A. 2002
- The prevalence of positive soluble fibrin and D-DIMER results in healthy asymptomatic pregnant women.. Blood. 20A-20A. 1999
- A latex D-Dimer reliably excludes venous. Thrombosis and Haemostasis. 258-258. 1999
- Use of an enzyme immunoassay (EIA) for soluble fibrin to exclude the diagnosis of deep vein thrombosis. Thrombosis and Haemostasis. 406-407. 1999
- Heparin binds to tissue factor: An explanation for heparin's limited effect on the prothrombin time.. Blood. 1290-1290. 1997
- The morphology of acute leukemia with 15;17 translocation: Further variants of APL, implications in regard to early ATRA therapy.. Blood. 3079-3079. 1995
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journal articles
- Sex differences in treatment strategies for pulmonary embolism in older adults: The SERIOUS-PE study of RIETE participants and US Medicare beneficiaries.. Vascular Medicine. 1358863X241292023. 2024
- Knowledge and raising awareness are the CURES for alleviating sex disparities in PE care.. Thrombosis Research. 243:109147. 2024
- Values and preferences towards the use of prophylactic low-molecular-weight heparin during pregnancy: a convergent mixed-methods secondary analysis of data from the decision analysis in shared decision making for thromboprophylaxis during pregnancy (DASH-TOP) study.. Thrombosis Journal. 22:81. 2024
- Assessment of a venous thromboembolism prophylaxis shared decision-making intervention (DASH-TOP) using the decisional conflict scale: a mixed-method study. BMC Medical Informatics and Decision Making. 23:250. 2023
- Decision Analysis in SHared decision making for Thromboprophylaxis during Pregnancy (DASH-TOP): a sequential explanatory mixed-methods pilot study. BMJ Evidence-Based Medicine. 28:309-319. 2023
- Sex-Related Differences in Patient Characteristics, Risk Factors, and Symptomatology in Older Adults with Pulmonary Embolism: Findings from the SERIOUS-PE Study. Seminars in Thrombosis and Hemostasis. 49:725-735. 2023
- Multidisciplinary care of the pregnant patient with or at risk for venous thromboembolism: a recommended toolkit from the Foundation for Women and Girls with Blood Disorders Thrombosis Subcommittee. Journal of Thrombosis and Haemostasis. 21:1432-1440. 2023
- Superficial vein thrombosis in pregnancy: what we did not know could hurt our patients. The Lancet Haematology. 10:e313-e314. 2023
- Women’s values and preferences on low-molecular-weight heparin and pregnancy: a mixed-methods systematic review. BMC Pregnancy and Childbirth. 22:747. 2022
- Sex Differences in PrEsentation, Risk Factors, Drug and Interventional Therapies, and OUtcomes of Elderly PatientS with Pulmonary Embolism: Rationale and design of the SERIOUS-PE study. Thrombosis Research. 214:122-131. 2022
- Women's representation in venous thromboembolism randomized trials and registries: The illustrative example of direct oral anticoagulants for acute treatment. Contemporary Clinical Trials. 115:106714-106714. 2022
- Pregnancy-related venous thromboembolism: Progress but questions remain. European Journal of Internal Medicine. 97:32-33. 2022
- Diagnosis of deep vein thrombosis with D-dimer adjusted to clinical probability: prospective diagnostic management study. The BMJ. 376:e067378-e067378. 2022
- More work needed on decision analysis for shared decision-making: A scoping review. Journal of Clinical Epidemiology. 141:106-120. 2022
- Special series on challenging anticoagulation cases: Experience counts when guidelines fall short. Thrombosis Research. 208:198-198. 2021
- How to write a guideline: a proposal for a manuscript template that supports the creation of trustworthy guidelines. Blood Advances. 5:4721-4726. 2021
- “Part of the Ritual”: Exploring Patient and Physician Decision Making Regarding Anticoagulation Use in Obstetric Antiphospholipid Syndrome. Thrombosis and Haemostasis. 121:1353-1360. 2021
- 2021 Update of the International Council for Standardization in Haematology Recommendations for Laboratory Measurement of Direct Oral Anticoagulants. Thrombosis and Haemostasis. 121:1008-1020. 2021
- Postoperative low molecular weight heparin bridging treatment for patients at high risk of arterial thromboembolism (PERIOP2): double blind randomised controlled trial. The BMJ. 373:n1205-n1205. 2021
- COVID-19 in thrombosis research: An editorial perspective. Thrombosis Research. 201:147-150. 2021
- Systematic review and meta-analysis of outcomes in patients with suspected pulmonary embolism. Blood Advances. 5:2237-2244. 2021
- Pulmonary Embolism in Pregnancy. Seminars in Respiratory and Critical Care Medicine. 42:284-298. 2021
- Decision Analysis in SHared decision making for Thromboprophylaxis during Pregnancy (DASH-TOP): a sequential explanatory mixed methods pilot study protocol. BMJ Open. 11:e046021-e046021. 2021
- Rivaroxaban Compared to Placebo for the Treatment of Leg Superficial Vein Thrombosis: A Randomized Trial. Seminars in Thrombosis and Hemostasis. 46:977-985. 2020
- The challenges and lessons learned in conducting clinical trials in pregnant women with antiphospholipid syndrome. Thrombosis Research. 194:54-56. 2020
- Systematic review and meta-analysis of test accuracy for the diagnosis of suspected pulmonary embolism. Blood Advances. 4:4296-4311. 2020
- Systematic review and meta-analysis of outcomes in patients with suspected deep vein thrombosis. Blood Advances. 4:2779-2788. 2020
- Diagnosis of deep vein thrombosis of the upper extremity: a systematic review and meta-analysis of test accuracy. Blood Advances. 4:2516-2522. 2020
- Methodology for the American Society of Hematology VTE guidelines: current best practice, innovations, and experiences. Blood Advances. 4:2351-2365. 2020
- Diagnosis of deep vein thrombosis of the lower extremity: a systematic review and meta-analysis of test accuracy. Blood Advances. 4:1250-1264. 2020
- The risk and prevention of venous thromboembolism in the pregnant traveller. Journal of Travel Medicine. 27:taz091. 2020
- Ability of a single negative ultrasound to rule out deep vein thrombosis in pregnant women: A systematic review and meta‐analysis. Journal of Thrombosis and Haemostasis. 18:373-380. 2020
- Subsegmental pulmonary embolism: May not be a killer but indicates significant risk. Thrombosis Research. 185:180-182. 2020
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Diagnosis of Pulmonary Embolism with
d -Dimer Adjusted to Clinical Probability. New England Journal of Medicine. 381:2125-2134. 2019 - Perioperative Management of Patients With Atrial Fibrillation Receiving a Direct Oral Anticoagulant. JAMA Internal Medicine. 179:1469-1469. 2019
- American Society of Hematology 2018 guidelines for management of venous thromboembolism: diagnosis of venous thromboembolism. Blood Advances. 2:3226-3256. 2018
- American Society of Hematology 2018 guidelines for management of venous thromboembolism: venous thromboembolism in the context of pregnancy. Blood Advances. 2:3317-3359. 2018
- Erratum to: The Perioperative Anticoagulant Use for Surgery Evaluation (PAUSE) Study for Patients on a Direct Oral Anticoagulant who Need an Elective Surgery or Procedure: Design and Rationale. Thrombosis and Haemostasis. 118:1679-1680. 2018
- Questioning the use of an age‐adjusted D‐dimer threshold to exclude venous thromboembolism: reply. Journal of Thrombosis and Haemostasis. 16:1448-1450. 2018
- International Council for Standardization in Haematology (ICSH) Recommendations for Laboratory Measurement of Direct Oral Anticoagulants. Thrombosis and Haemostasis. 118:437-450. 2018
- The Society for Obstetric Anesthesia and Perinatology Consensus Statement on the Anesthetic Management of Pregnant and Postpartum Women Receiving Thromboprophylaxis or Higher Dose Anticoagulants. Anesthesia and Analgesia. 126:928-944. 2018
- How I treat heavy menstrual bleeding associated with anticoagulants. Blood. 130:2603-2609. 2017
- Management of hereditary antithrombin deficiency in pregnancy. Thrombosis Research. 157:41-45. 2017
- Comparison of clinical probability-adjusted D-dimer and age-adjusted D-dimer interpretation to exclude venous thromboembolism. Thrombosis and Haemostasis. 117:1937-1943. 2017
- The Perioperative Anticoagulant Use for Surgery Evaluation (PAUSE) Study for Patients on a Direct Oral Anticoagulant Who Need an Elective Surgery or Procedure: Design and Rationale. Thrombosis and Haemostasis. 117:2415-2424. 2017
- Questioning the use of an age‐adjusted D‐dimer threshold to exclude venous thromboembolism: analysis of individual patient data from two diagnostic studies: reply. Journal of Thrombosis and Haemostasis. 14:2555-2556. 2016
- Questioning the use of an age‐adjusted D‐dimer threshold to exclude venous thromboembolism: analysis of individual patient data from two diagnostic studies. Journal of Thrombosis and Haemostasis. 14:1953-1959. 2016
- International Society on Thrombosis and Haemostasis core curriculum project: core competencies in clinical thrombosis and hemostasis: comment. Journal of Thrombosis and Haemostasis. 14:1316-1317. 2016
- Low molecular weight heparin to prevent postpartum venous thromboembolism: A pilot study to assess the feasibility of a randomized, open-label trial. Thrombosis Research. 142:17-20. 2016
- Rapid quantitative D‐dimer to exclude pulmonary embolism: a prospective cohort management study. Journal of Thrombosis and Haemostasis. 14:504-509. 2016
- Guidance for the treatment and prevention of obstetric-associated venous thromboembolism. Journal of Thrombosis and Thrombolysis. 41:92-128. 2016
- Women’s values and preferences and health state valuations for thromboprophylaxis during pregnancy: A cross-sectional interview study. Thrombosis Research. 140:22-29. 2016
- Combination of 4Ts score and PF4/H-PaGIA for diagnosis and management of heparin-induced thrombocytopenia: prospective cohort study. Blood. 126:597-603. 2015
- Women’s values and preferences for thromboprophylaxis during pregnancy: a comparison of direct-choice and decision analysis using patient specific utilities. Thrombosis Research. 136:341-347. 2015
- Anticoagulation and in vitro fertilization and ovarian stimulation. Hematology. American Society of Hematology. Education Program. 2014:379-386. 2014
- Low-molecular-weight heparin for prevention of placenta-mediated pregnancy complications: protocol for a systematic review and individual patient data meta-analysis (AFFIRM). Systematic Reviews. 3:69. 2014
- Exclusion of deep vein thrombosis using the Wells rule in clinically important subgroups: individual patient data meta-analysis. The BMJ. 348:g1340-g1340. 2014
- Exclude DVT with a clinical decision rule. Huisarts en Wetenschap. 57. 2014
- Superficial venous thrombosis: recognizing the risk. Blood. 122:4159-4160. 2013
- Recommendations for prophylaxis of pregnancy‐related venous thromboembolism in carriers of inherited thrombophilia. Comment on the 2012 ACCP guidelines: a rebuttal. Journal of Thrombosis and Haemostasis. 11:1782-1784. 2013
- Preventing thrombophilia-related complications of pregnancy: an update. Expert Review of Hematology. 6:287-300. 2013
- D-Dimer Assays in Diagnosis and Management of Thrombotic and Bleeding Disorders. Seminars in Thrombosis and Hemostasis. 38:673-682. 2012
- Using an age-dependent D-dimer cut-off value increases the number of older patients in whom deep vein thrombosis can be safely excluded. Haematologica. 97:1507-1513. 2012
- Accuracy and safety of 99mTc-labeled anti-D-dimer (DI-80B3) Fab’ fragments (ThromboView®) in the diagnosis of deep vein thrombosis: A phase II study. Thrombosis Research. 130:381-389. 2012
- Diagnosis of DVT. Chest. 141:e351S-e418S. 2012
- VTE, Thrombophilia, Antithrombotic Therapy, and Pregnancy. Chest. 141:e691S-e736S. 2012
- The Effect of Prothrombotic Blood Abnormalities on Risk of Deep Vein Thrombosis in Users of Hormone Replacement Therapy. Clinical and Applied Thrombosis/Hemostasis. 17:E106-E113. 2011
- Pregnancy-Associated Venous Thromboembolism: Prevention and Treatment. Seminars in Hematology. 48:271-284. 2011
- Consultative Hematology: The Pregnant Patient Pregnancy Loss. Hematology. American Society of Hematology. Education Program. 2010:166-172. 2010
- Preventing thrombophilia-related complications of pregnancy. Expert Review of Hematology. 2:183-196. 2009
- Venous thromboembolism in pregnancy: diagnosis, management and prevention. Thrombosis and Haemostasis. 101:428-438. 2009
- Delayed‐onset HIT caused by low‐molecular‐weight heparin manifesting during fondaparinux prophylaxis. American Journal of Hematology. 83:876-878. 2008
- Differences in clinical presentation of deep vein thrombosis in men and women. Journal of Thrombosis and Haemostasis. 6:1713-1719. 2008
- D‐dimer testing is useful to exclude deep vein thrombosis in elderly outpatients. Journal of Thrombosis and Haemostasis. 6:1072-1076. 2008
- Venous Thromboembolism, Thrombophilia, Antithrombotic Therapy, and Pregnancy. Chest. 133:844S-886S. 2008
- Accuracy and usefulness of a clinical prediction rule and D-dimer testing in excluding deep vein thrombosis in cancer patients. Thrombosis Research. 123:177-183. 2008
- Management of Pregnant Women with Thrombophilia or a History of Venous Thromboembolism. Hematology. American Society of Hematology. Education Program. 2007:143-150. 2007
- Prophylaxis of Thromboembolism in Critical Care (PROTECT) Trial: a pilot study. Journal of Critical Care. 20:364-372. 2005
- Are brand-name and generic warfarin interchangeable? A survey of Ontario patients and physicians.. Journal of Population Therapeutics and Clinical Pharmacology. 12:e229-e239. 2005
- The multiple faces of the partial thromboplastin time APTT. Journal of Thrombosis and Haemostasis. 2:2250-2252. 2004
- The multiple faces of the partial thromboplastin time APTT. Journal of Thrombosis and Haemostasis. 2:2254-2256. 2004
- Deep-Vein Thrombosis. New England Journal of Medicine. 351:2133-2134. 2004
- Treatment of Deep-Vein Thrombosis. New England Journal of Medicine. 351:268-277. 2004
- Emerging Anticoagulant Drugs. Arteriosclerosis, Thrombosis and Vascular Biology. 23:1491-1500. 2003
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A Diagnostic Strategy Involving a Quantitative Latex
d -Dimer Assay Reliably Excludes Deep Venous Thrombosis. ACP journal club. 138:787-787. 2003 - Imaging Characteristics of a Novel Technetium Tc 99m–Labeled Platelet Glycoprotein IIb/IIIa Receptor Antagonist in Patients With Acute Deep Vein Thrombosis or a History of Deep Vein Thrombosis. JAMA Internal Medicine. 163:452-452. 2003
- Treatment and prophylaxis of venous thromboembolism during pregnancy. Thrombosis Research. 108:97-106. 2002
- Questioning the Treatment of Venous Thromboembolism. ACP journal club. 137:144-144. 2002
- Questioning the Treatment of Venous Thromboembolism. ACP journal club. 137:145-145. 2002
- A negative quantitative latex D-dimer assay helped to rule out venous thromboembolism. BMJ Evidence-Based Medicine. 6:188-188. 2001
- A Latex D-Dimer Reliably Excludes Venous Thromboembolism. JAMA Internal Medicine. 161:447-447. 2001
- Use of a Fixed Activated Partial Thromboplastin Time Ratio to Establish a Therapeutic Range for Unfractionated Heparin. JAMA Internal Medicine. 161:385-385. 2001
- Effect of hormone replacement therapy on the endogenous thrombin potential. Blood. 96. 2000
- Endogenous thrombin potential and the risk of venous thromboembolism. Blood. 96. 2000
- Phospholipid micelles, but not vesicles, neutralize heparin: an explanation for the minimal effect of heparin on the prothrombin time. Blood. 96. 2000
- Criteria for evaluating evidence that laboratory abnormalities are associated with the development of venous thromboembolism.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 163:1016-1021. 2000
- Recurrent Venous Thrombosis and Heparin Therapy. JAMA Internal Medicine. 159:2029-2029. 1999
- Treatment of Venous Thromboembolism. Thrombosis and Haemostasis. 82:870-877. 1999
- Risk of Fatal Pulmonary Embolism in Patients With Treated Venous Thromboembolism. Journal of the American Medical Association (JAMA). 279:458-458. 1998
- Morphology of acute promyelocytic leukemia with cytogenetic or molecular evidence for the diagnosis: Characterization of additional microgranular variants. American Journal of Hematology. 56:131-142. 1997
- The special problems of thromboembolism in pregnancy. IM - Internal Medicine. 18:121-126+131. 1997
- Thrombosis in pregnancy. Current Opinion in Hematology. 4:335-343. 1997