Pyrrolidinones Concept

subject area of

• A novel method to enhance the stability of alginate-poly-L-lysine-alginate microcapsules  Academic Article
• ATP stimulates Ca2+-waves and gene expression in cultured human pulmonary fibroblasts  Academic Article
• An in Vivo Comparison of the Kinetics of Protein and Lipid Deposition on Group II and Group IV Frequent-Replacement Contact Lenses  Academic Article
• Biocompatible poly(N-vinyllactam)-based materials with environmentally-responsive permeability  Academic Article
• Biological properties of photocrosslinked alginate microcapsules  Academic Article
• Change in expression of vesicular protein synapsin II by chronic treatment with D2 allosteric modulator PAOPA  Academic Article
• Design, Synthesis, X-ray Analysis, and Dopamine Receptor-Modulating Activity of Mimics of the "C5" Hydrogen-Bonded Conformation in the Peptidomimetic 2-Oxo-3(R)-[(2(S)-pyrrolidinylcarbonyl)amino]-1-pyrrolidineacetamide  Academic Article
• EGFR-PLCγ1 signaling mediates high glucose-induced PKCβ1-Akt activation and collagen I upregulation in mesangial cells  Academic Article
• Effects of the Dopamine D2 Allosteric Modulator, PAOPA, on the Expression of GRK2, Arrestin-3, ERK1/2, and on Receptor Internalization  Academic Article
• Emesis induced by inhibitors of type IV cyclic nucleotide phosphodiesterase (PDE IV) in the ferret  Academic Article
• Hydrophobically-modified poly(vinyl pyrrolidone) as a physically-associative, shear-responsive ophthalmic hydrogel  Academic Article
• Intracellular targeting, interaction with Src homology 3 (SH3) domains and rolipram-detected conformational switches in cAMP-specific PDE4A phosphodiesterase  Academic Article
• Lipid and protein deposition of N-vinyl pyrrolidone-containing group II and group IV frequent replacement contact lenses.  Academic Article
• Low energy photon attenuation measurements of hydrophilic materials for tissue equivalent phantoms  Academic Article
• Modulation of Dopamine Receptor Agonist-Induced Rotational Behavior in 6-OHDA-Lesioned Rats by a Peptidomimetic Analogue of Pro-Leu-Gly-NH2 (PLG)  Academic Article
• Modulation of agonist stimulated adenylyl cyclase and GTPase activity by l-pro-l-leu-glycinamide and its peptidomimetic analogue in rat striatal membranes  Academic Article
• Modulation of high-affinity CNS dopamine D2 receptor by l-pro-l-leu-glycinamide (PLG) analogue  Conference Paper
• PAOPA, a potent analogue of Pro-Leu-glycinamide and allosteric modulator of the dopamine D2 receptor, prevents NMDA receptor antagonist (MK-801)-induced deficits in social interaction in the rat: Implications for the treatment of negative symptoms in schizophrenia  Academic Article
• PAOPA, a potent dopamine D2 receptor allosteric modulator, prevents and reverses behavioral and biochemical abnormalities in an amphetamine-sensitized preclinical animal model of schizophrenia  Academic Article
• Platelet derived growth factor-evoked Ca2+ wave and matrix gene expression through phospholipase C in human pulmonary fibroblast  Academic Article
• Preclinical pharmacokinetic and toxicological evaluation of MIF-1 peptidomimetic, PAOPA: Examining the pharmacology of a selective dopamine D2 receptor allosteric modulator for the treatment of schizophrenia  Academic Article
• Pro-Leu-glycinamide and its peptidomimetic, PAOPA, attenuate haloperidol induced vacuous chewing movements in rat: A model of human tardive dyskinesia  Academic Article
• Protection Against MPTP Treatment by an Analog of Pro-Leu-Gly-NH2 (PLG, MIF-1)  Academic Article
• Quantitative chemical mapping of sodium acrylate- and N-vinylpyrrolidone-enhanced alginate microcapsules  Academic Article
• U73122 affects the equilibria between the phosphoinositides as well as phospholipase C activity in unstimulated and thrombin-stimulated human and rabbit platelets.  Academic Article
• iso-Lactam and reduced amide analogues of the peptidomimetic dopamine receptor modulator 3(R)-[(2(S)-Pyrrolidinylcarbonyl)amino]-2-oxo-1-pyrrolidineacetamide  Academic Article
• l-Prolyl-l-leucyl-glycinamide and its peptidomimetic analog 3(R)-[(2(S)-pyrrolidylcarbonyl)amino]-2-oxo-1-pyrrolidineacetamide (PAOPA) attenuate haloperidol-induced c-fos expression in the striatum☆  Academic Article