An in Vivo Comparison of the Kinetics of Protein and Lipid Deposition on Group II and Group IV Frequent-Replacement Contact Lenses

PURPOSE: To investigate the degree and rate of deposition of protein and lipid on FDA group II and group IV contact lens materials over a period of up to 28 days of wear. METHODS: Twenty-two subjects wore a group IV lens (Acuvue) and a group II lens (Soflens 66) in a randomized, cross-over study. The lenses were randomly worn for periods between 1 and 28 days and then collected for laboratory-based deposition analysis.