Journal article
A novel method to enhance the stability of alginate-poly-L-lysine-alginate microcapsules
Abstract
Implantation of microencapsulated recombinant cells is an alternative approach to gene therapy. These genetically-engineered cells enclosed in microcapsules to deliver therapeutic recombinant products have been effective in treating several murine models of human diseases. However, the most commonly used microcapsules fabricated from alginate ionically cross-linked with calcium suffer from loss of long-term mechanical stability. We now report …
Authors
Wang MS; Childs RF; Chang PL
Journal
Journal of Biomaterials Science Polymer Edition, Vol. 16, No. 1, pp. 89–111
Publisher
Taylor & Francis
Publication Date
January 2005
DOI
10.1163/1568562052843302
ISSN
0920-5063