Piperazines Concept

subject area of

• 5-HT2A/C receptors do not mediate the attenuation of compulsive checking by mCPP in the quinpirole sensitization rat model of obsessive–compulsive disorder (OCD)  Academic Article
• A Canadian paediatric brain tumour consortium (CPBTC) phase II molecularly targeted study of imatinib in recurrent and refractory paediatric central nervous system tumours  Academic Article
• A PET study of effects of chronic 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) on serotonin markers in Göttingen minipig brain  Academic Article
• An optimum prophylactic dose of prasugrel monotherapy may safely and effectively prevent the development of experimental thrombotic strokes  Academic Article
• Antiarrhythmic effects of azimilide in atrial fibrillation: efficacy and dose-response  Academic Article
• Antiarrhythmic effects of azimilide in paroxysmal supraventricular tachycardia: Efficacy and dose-response  Academic Article
• Antiarrhythmic efficacy of azimilide in patients with atrial fibrillation. Maintenance of sinus rhythm after conversion to sinus rhythm.  Academic Article
• Antidotes for Novel Oral Anticoagulants  Academic Article
• Antimanic Response to Aripiprazole in Bipolar I Disorder Patients Is Independent of the Agitation Level at Baseline  Academic Article
• Antiplatelet Therapy and Cardiac Surgery: Review of Recent Evidence and Clinical Implications  Academic Article
• Antiviral activity and safety of aplaviroc, a CCR5 antagonist, in combination with lopinavir/ritonavir in HIV-infected, therapy-naïve patients: results of the EPIC study (CCR100136)  Academic Article
• Aripiprazole Augmentation in the Treatment of Military-Related PTSD with Major Depression: a retrospective chart review  Academic Article
• Aripiprazole Reduces Alcohol Use  Academic Article
• Aripiprazole-Associated QTc Prolongation in a Geriatric Patient  Academic Article
• Assessing exertional dyspnea in patients with idiopathic pulmonary fibrosis  Academic Article
• Asymptomatic or “Silent” Atrial Fibrillation  Academic Article
• Azimilide for the Treatment of Atrial Fibrillation, Atrial Flutter, and Paroxysmal Supraventricular Tachycardia: Results of a Randomized Trial and Insights on the Concordance of Symptoms and Recurrent Arrhythmias  Academic Article
• Bulbocavernosus reflex testing: a preliminary study on the prognostic factors for potency and response to sildenafil citrate after bilateral nerve-sparing radical prostatectomy  Academic Article
• CSB interacts with BRCA1 in late S/G2 to promote MRN- and CtIP-mediated DNA end resection  Academic Article
• Characterization of α-Adrenoceptors in Canine Mesenteric Vein  Academic Article
• Ciraparantag as a potential universal anticoagulant reversal agent  Academic Article
• Ciraparantag for enoxaparin reversal: Adding to the evidence  Academic Article
• Ciraparantag: the next anticoagulant airbag?  Academic Article
• Clinical implications of reversal agents for direct oral anticoagulants  Academic Article
• Commentary: sildenafil in phallometric testing--an evidence-based assessment of sexual offenders.  Academic Article
• Comparative In Vitro Activities of Ciprofloxacin, Gemifloxacin, Grepafloxacin, Moxifloxacin, Ofloxacin, Sparfloxacin, Trovafloxacin, and Other Antimicrobial Agents against Bloodstream Isolates of Gram-Positive Cocci  Academic Article
• Comparative efficacy and safety of first-line antiretroviral therapy for the treatment of HIV infection: a systematic review and network meta-analysis  Academic Article
• Corrected QT interval prolongation after an overdose of escitalopram, morphine, oxycodone, zopiclone and benzodiazepines  Academic Article
• Correlation between serotonin synthesis and 5-HT1A receptor binding in the living human brain: A combined α-[11C]MT and [18F]MPPF positron emission tomography study  Conference Paper
• Current Incidence and Outcomes of Gastrointestinal Mesenchymal Tumors Including Gastrointestinal Stromal Tumors  Academic Article
• Current Perspectives in the Pharmacological Studies of Store-Operated Ca2+ Entry Blockers.  Academic Article
• Deep molecular responses achieved in patients with CML-CP who are switched to nilotinib after long-term imatinib  Academic Article
• Design, Synthesis, and Dopamine Receptor Modulating Activity of Diketopiperazine Peptidomimetics of l-Prolyl-l-leucylglycinamide  Academic Article
• Differences in the Mechanisms of Proapoptotic BH3 Proteins Binding to Bcl-XL and Bcl-2 Quantified in Live MCF-7 Cells  Academic Article
• Differential effects of putative protein kinase C inhibitors on contraction of rat aortic smooth muscle  Academic Article
• Dose-response relations of azimilide in the management of symptomatic, recurrent, atrial fibrillation  Academic Article
• Dual antiplatelets for 30 mo after drug-eluting stents reduced stent thrombosis and CV and cerebrovascular events  Academic Article
• Effect in vitro on platelet function of two compounds developed from the pyrimido-pyrimidines  Academic Article
• Effects of Asm-024, A Modulator of Acetylcholine Receptor Function, On Airway Responsiveness and Allergen-Induced Responses in Patients with Mild Asthma  Academic Article
• Effects of AttM lactonase on the pathogenicity of Streptomyces scabies  Academic Article
• Effects of Azimilide on Heart Rate and ECG Conduction Intervals during Sinus Rhythm in Patients with a History of Atrial Fibrillation  Academic Article
• Effects of oxatomide compared with chlorpheniramine in allergic rhinoconjunctivitis  Academic Article
• Effects of phenobarbitone, cinnarizine, and zoxazolamine on the development of right ventricular hypertrophy and hypertensive pulmonary vascular disease in rats treated with monocrotaline  Academic Article
• Effects of the serotonergic agonist mCPP on male rats in the quinpirole sensitization model of obsessive–compulsive disorder (OCD)  Academic Article
• Efficacy of Azimilide for the Maintenance of Sinus Rhythm in Patients With Paroxysmal Atrial Fibrillation in the Presence and Absence of Structural Heart Disease  Academic Article
• Energy-stress-mediated AMPK activation inhibits ferroptosis  Academic Article
• Enhancing Endocrine Therapy Combination Strategies for the Treatment of Postmenopausal HR+/HER2– Advanced Breast Cancer  Academic Article
• Erectile dysfunction in spinal cord injury: a cost-utility analysis  Academic Article
• Esophageal gastrointestinal stromal tumor: report of 7 patients  Academic Article
• Focused 2012 Update of the Canadian Cardiovascular Society Guidelines for the Use of Antiplatelet Therapy  Academic Article
• Haloperidol (but not ziprasidone) withdrawal potentiates sensitization to the hyperlocomotor effect of cocaine in mice  Academic Article
• Hormonal and Subjective Responses to Intravenous m-Chlorophenylpiperazine in Women With Seasonal Affective Disorder  Academic Article
• Hormonal and Subjective Responses to Intravenous meta-Chlorophenylpiperazine in Bulimia Nervosa  Academic Article
• Imatinib Mesylate in Patients With Adenoid Cystic Cancers of the Salivary Glands Expressing c-kit: A Princess Margaret Hospital Phase II Consortium Study  Academic Article
• Imatinib for Melanomas Harboring Mutationally Activated or Amplified KIT Arising on Mucosal, Acral, and Chronically Sun-Damaged Skin  Academic Article
• Imatinib mesylate in children and adolescents with cancer  Academic Article
• Impact of sildenafil on marital and sexual adjustment in patients and their wives after radiotherapy and short-term androgen suppression for prostate cancer  Academic Article
• Implications of variability in definition and reporting of major bleeding in randomized trials of oral P2Y12 inhibitors for acute coronary syndromes  Academic Article
• Interaction of NMDA and Dopamine D2L Receptors in Human Neuroblastoma SH-SY5Y Cells  Academic Article
• Interactions of pro-apoptotic BH3 proteins with anti-apoptotic Bcl-2 family proteins measured in live MCF-7 cells using FLIM FRET  Academic Article
• Lack of effect of antipsychotics on BNDF and NGF levels in hippocampus of Wistar rats  Academic Article
• Measuring quality of life: The development and initial validation of the Patient-Reported Erectile Function Assessment instrument  Academic Article
• Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants  Academic Article
• Melatonin and zopiclone as pharmacologic aids to facilitate crew rest.  Academic Article
• Metabolic response by FDG-PET to imatinib correlates with exon 11 KIT mutation and predicts outcome in patients with mucosal melanoma  Academic Article
• Mitapivat versus Placebo for Pyruvate Kinase Deficiency  Academic Article
• Modelling the Cost Effectiveness of Antidepressant Treatment in Primary Care  Academic Article
• Modulation of Dopamine D₂ Receptor Expression by an NMDA Receptor Antagonist in Rat Brain  Academic Article
• Modulation ofN-methyl-d-aspartate (NMDA) antagonist-induced darting behaviour by the peptidomimetic PAMTA  Academic Article
• Monitoring and reversal of direct oral anticoagulants  Academic Article
• NOAC monitoring, reversal agents, and post-approval safety and effectiveness evaluation: A cardiac safety research consortium think tank  Academic Article
• Nefazodone in Social Phobia  Academic Article
• Nefazodone in the Treatment of Generalized Social Phobia  Academic Article
• New antithrombotic agents—insights from clinical trials  Academic Article
• Novel oral anticoagulants and reversal agents: Considerations for clinical development  Academic Article
• ORIGINAL RESEARCH—ED PHARMACOTHERAPY: Can an Educational Program Optimize PDE5i Therapy? A Study of Canadian Primary Care Practices  Academic Article
• Oral, Direct Factor Xa Inhibitors in Development for the Prevention and Treatment of Thromboembolic Diseases  Academic Article
• Osimertinib in UntreatedEGFR-Mutated Advanced Non–Small-Cell Lung Cancer  Academic Article
• Palbociclib in hormone receptor positive advanced breast cancer: A cost-utility analysis  Academic Article
• Palbociclib plus letrozole versus placebo plus letrozole in Asian postmenopausal women with oestrogen receptor–positive/human epidermal growth factor receptor 2–negative advanced breast cancer: Primary results from PALOMA-4  Academic Article
• Persistent genital arousal disorder: a clinical challenge  Academic Article
• Pharmacokinetics, safety, activity, and biomarker analysis of palbociclib plus letrozole as first-line treatment for ER+/HER2– advanced breast cancer in Chinese women  Academic Article
• Pharmacological and immunocytochemical characterization of subtypes of alpha-1 adrenoceptors in dog aorta.  Academic Article
• Platelet ADP-receptor antagonists for cardiovascular disease: past, present and future  Academic Article
• Preparation, Characterization, and Screening of a High Affinity Organometallic Probe for α-Adrenergic Receptors  Academic Article
• Quantitative autoradiography of ligands for dopamine receptors and transporters in brain of Göttingen minipig: Comparison with results in vivo  Academic Article
• Randomized, Double‐Blinded, Placebo‐Controlled Crossover Trial of Treating Erectile Dysfunction with Sildenafil After Radiotherapy and Short‐Term Androgen Deprivation Therapy: Results of RTOG 0215  Academic Article
• Reversal agents for non-vitamin K antagonist oral anticoagulants  Academic Article
• Role of phenotypic and genetic testing in managing clopidogrel therapy  Academic Article
• Safety of Sildenafil in Infants*  Academic Article
• Secondary Prevention of HAPE in a Mount Everest Summiteer  Academic Article
• Sensitivity to protein kinase C inhibitors of nicardipine-insensitive component of high K+ contracture in rat and guinea-pig aorta  Academic Article
• Separate mechanisms for development and performance of compulsive checking in the quinpirole sensitization rat model of obsessive-compulsive disorder (OCD)  Academic Article
• Serotonergic agents in the treatment of social phobia in children and adolescents: A case series  Academic Article
• Serotonin Syndrome Associated With Nefazodone and Paroxetine  Academic Article
• Sildenafil citrate (VIAGRA): an oral treatment for erectile function with activity for up to four hours' duration.  Academic Article
• Stability strengths oncogenic activity  Academic Article
• Symptoms at the time of arrhythmia recurrence in patients receiving azimilide for control of atrial fibrillation or flutter: results from randomized trials  Academic Article
• Thaxtomin A-deficient endophytic Streptomyces sp. enhances plant disease resistance to pathogenic Streptomyces scabies  Academic Article
• The Non-Vitamin K Antagonist Oral Anticoagulants in Heart Disease: Section V—Special Situations  Academic Article
• The Pursuit of Clinically Relevant Measures of Platelet Function After Antiplatelet Drug Therapy⁎⁎Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology.  Academic Article
• The Treatment of Heart Failure  Academic Article
• The effect of intravenously administered almitrine, a peripheral chemoreceptor agonist, on patients with chronic air-flow obstruction.  Academic Article
• The novel analgesic, F 13640, produces intra- and postoperative analgesia in a rat model of surgical pain  Academic Article
• Treatment Satisfaction with Sildenafil in a Canadian Real-Life Setting. A 6-Month Prospective Observational Study of Primary Care Practices  Academic Article
• Treatment of primary insomnia.  Academic Article
• Uptake and binding of the serotonin 5-HT1A antagonist [18F]-MPPF in brain of rats: Effects of the novel P-glycoprotein inhibitor tariquidar  Academic Article
• Vardenafil Improves Erectile Function in Men with Erectile Dysfunction Irrespective of Disease Severity and Disease Classification  Academic Article
• Vardenafil Improves Patient Satisfaction with Erection Hardness, Orgasmic Function, and Overall Sexual Experience, While Improving Quality of Life in Men with Erectile Dysfunction  Academic Article
• Vardenafil and Weaning from Inhaled Nitric Oxide: Effect on Pulmonary Hypertension in ARDS  Academic Article
• When and how to use antidotes for the reversal of direct oral anticoagulants: guidance from the SSC of the ISTH  Academic Article
• Will prasugrel supersede clopidogrel for acute coronary syndromes?  Academic Article
• XXIII International Association for Comparative Research on Leukemia and Related Diseases Symposium: from Molecular Pathogenesis to Targeted Therapy in Leukemia and Solid Tumors  Conference Paper
• p53: The pivot between cell cycle arrest and senescence  Academic Article