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Characterization of α-Adrenoceptors in Canine...
Journal article

Characterization of α-Adrenoceptors in Canine Mesenteric Vein

Abstract

The alpha-adrenergic receptors (alpha-ARs) in canine mesenteric vein (DMV) were studied by using nonselective agonists and selective antagonists in functional studies and in ligand binding to classify the subtypes present. Based on functional studies of phenylephrine (PE)-induced contractions and ligand-binding interactions of [3H]-prazosin with prazosin (PR), WB 4101 (WB), 5-methylurapidil (5-MU), BMY 7378, and SK&F 105854, and pretreatment …

Authors

Daniel EE; Low AM; Lu-Chao H; Gaspar V; Kwan C-Y

Journal

Journal of Cardiovascular Pharmacology, Vol. 30, No. 5, pp. 591–598

Publisher

Wolters Kluwer

Publication Date

11 1997

DOI

10.1097/00005344-199711000-00009

ISSN

0160-2446