Frailty Concept

subject area of

• 30-Day Mortality among Very Old Patients Admitted to European Intensive Care Units for Major Trauma  Journal Articles
• A Brief Measure of Life Participation for People with COPD: Validation of the Computer Adaptive Test Version of the Late Life Disability Instrument  Journal Articles
• A comparison of very old patients admitted to intensive care unit after acute versus elective surgery or intervention  Journal Articles
• A realist review to understand the efficacy and outcomes of interventions designed to minimise, reverse or prevent the progression of frailty  Journal Articles
• Accumulation of Deficits as a Key Risk Factor for Cardiovascular Morbidity and Mortality: A Pooled Analysis of 154 000 Individuals  Journal Articles
• Age- and sex-specific associations of frailty with mortality and healthcare utilization in community-dwelling adults from Ontario, Canada  Journal Articles
• Aging and Frailty in First Nations Communities  Journal Articles
• An MDS-specific frailty index based on cumulative deficits adds independent prognostic information to clinical prognostic scoring  Journal Articles
• An overview of osteoporosis and frailty in the elderly  Journal Articles
• Applying the geriatric 5Ms in critical care: the ICU-5Ms  Journal Articles
• Assessing frailty in the intensive care unit: A reliability and validity study  Journal Articles
• Assessing patient frailty in plastic surgery: A systematic review  Journal Articles
• Assessing the Modified Frailty Index and Post-Operative Outcomes in Adhesive Small Bowel Obstruction: A Retrospective Cohort Study  Journal Articles
• Assessing the measurement properties of a Frailty Index across the age spectrum in the Canadian Longitudinal Study on Aging  Journal Articles
• Assessment of Frailty in Predicting Surgical Outcomes in Patients with Chronic Subdural Hematomas: Retrospective Chart Review  Journal Articles
• Assessments of Heart Failure and Frailty-Related Health Instability Provide Complementary and Useful Information for Home-Care Planning and Prognosis  Journal Articles
• Association between frailty, chronic conditions and socioeconomic status in community-dwelling older adults attending primary care: a cross-sectional study using practice-based research network data  Journal Articles
• Associations between Osteosarcopenia and Falls, Fractures, and Frailty in Older Adults: Results From the Canadian Longitudinal Study on Aging (CLSA)  Conferences
• Associations of Adverse Childhood Experiences with Frailty in Older Adults: A Cross-Sectional Analysis of Data from the Canadian Longitudinal Study on Aging  Journal Articles
• Automatic Radar-Based Step Length Measurement in the Home for Older Adults Living with Frailty  Journal Articles
• Barriers and facilitators to optimal supportive end-of-life palliative care in long-term care facilities: a qualitative descriptive study of community-based and specialist palliative care physicians’ experiences, perceptions and perspectives  Journal Articles
• Beyond the revised cardiac risk index: Validation of the hospital frailty risk score in non-cardiac surgery  Journal Articles
• Biomedicalization of end-of-life conversations with medically frail older adults - Malleable and senescent bodies  Journal Articles
• Body mass index is not suitable for assessing body composition in children with spastic cerebral palsy  Journal Articles
• COMPARISON OF FRAILTY SCORES IN NEWLY DIAGNOSED PATIENTS WITH MULTIPLE MYELOMA: A REVIEW  Journal Articles
• COVID-19 and the risk and trajectory of frailty in community- or institution-dwelling individuals: Protocol for systematic review and meta-analysis.  Journal Articles
• COVID-19 excess mortality among long-term care residents in Ontario, Canada  Journal Articles
• Challenges in implementing an advance care planning programme in long-term care  Journal Articles
• Characterizing Cluster-Based Frailty Phenotypes in a Multicenter Prospective Cohort of Kidney Transplant Candidates  Journal Articles
• Characterizing Frailty In Myeloproliferative Neoplasms: results from the ORCHID study  Journal Articles
• Clustering analysis of geriatric and acute characteristics in a cohort of very old patients on admission to ICU  Journal Articles
• Combining Frailty and Trabecular Bone Score Did Not Improve Predictive Accuracy in Risk of Major Osteoporotic Fractures  Journal Articles
• Comparing Biological Age Estimates Using Domain-Specific Measures From the Canadian Longitudinal Study on Aging  Journal Articles
• Comparison of Frailty Screening Instruments in the Emergency Department  Journal Articles
• Core requirements of frailty screening in the emergency department: an international Delphi consensus study  Journal Articles
• Defining high bleeding risk in patients undergoing percutaneous coronary intervention: a consensus document from the Academic Research Consortium for High Bleeding Risk  Journal Articles
• Delayed discharge and frailty, delirium and functional decline  Journal Articles
• Deprescribing Anticholinergic and Sedative Drugs to Reduce Polypharmacy in Frail Older Adults Living in the Community: A Randomized Controlled Trial  Journal Articles
• Development and testing of a lymphoma clinical trial-specific frailty index: a secondary analysis of the NCIC-CTG LY.12 clinical trial  Journal Articles
• Development and validation of the Fracture Risk Scale (FRS) that predicts fracture over a 1-year time period in institutionalised frail older people living in Canada: an electronic record-linked longitudinal cohort study  Journal Articles
• Development of a Medicare Health Outcomes Survey Deficit-Accumulation Frailty Index and Its Application to Older Patients With Newly Diagnosed Multiple Myeloma  Journal Articles
• Diabetes and Frailty: Revisiting the Converging Conditions  Journal Articles
• Dynamic frailty risk assessment among older adults with multiple myeloma: A population-based cohort study  Journal Articles
• Effectiveness of interventions to prevent pre-frailty and frailty progression in older adults: a systematic review  Journal Articles
• Encouraging older adults with pre-frailty and frailty to “MoveStrong”: an analysis of secondary outcomes for a pilot randomized controlled trial  Journal Articles
• Epigenetic age is associated with baseline and 3-year change in frailty in the Canadian Longitudinal Study on Aging  Journal Articles
• Evaluating frailty using the modified frailty index for colonic diverticular disease surgery: analysis of the national inpatient sample 2015–2019  Journal Articles
• Evaluation of a physiatrist-directed prehabilitation intervention in frail patients with colorectal cancer: a randomised pilot study protocol  Journal Articles
• Examining early and late onset of multimorbidity in the Canadian Longitudinal Study on Aging  Journal Articles
• Examining the Association between Frailty and Antibody Neutralization of SARS-CoV-2: A Multisite Retrospective Cohort Study  Journal Articles
• Examining the relationship between triage acuity and frailty to inform the care of older emergency department patients: Findings from a large Canadian multisite cohort study  Journal Articles
• Exploring the Impact of Age, Frailty, and Multimorbidity on the Effect of ICU Interventions: A Systematic Review of Randomized Controlled Trials  Journal Articles
• External validation of the FIRST trial’s simplified frailty score in a population-based cohort  Journal Articles
• FRAIL-AF Study: More Bleeding With DOACs Compared With VKAs in Patients With Frailty?  Journal Articles
• Factors partitioning physical frailty in people aging with HIV: A classification and regression tree approach  Journal Articles
• Fall Prevention Program Characteristics and Experiences of Older Adults and Program Providers in Canada: A Thematic Content Analysis  Journal Articles
• First Line Treatment of Newly Diagnosed Transplant Ineligible Multiple Myeloma: Recommendations from the Canadian Myeloma Research Group Consensus Guideline Consortium  Journal Articles
• Frailty Among Patients With Acute ST-Elevation Myocardial Infarction in the United States: The Impact of the Primary Percutaneous Coronary Intervention on In-Hospital Outcomes  Journal Articles
• Frailty Hinders Recovery From Influenza and Acute Respiratory Illness in Older Adults  Journal Articles
• Frailty Is Inversely Related to Age at Menopause and Elevated in Women Who Have Had a Hysterectomy: An Analysis of the Canadian Longitudinal Study on Aging  Journal Articles
• Frailty Predicts Postoperative Complications following Pancreaticoduodenectomy  Journal Articles
• Frailty and Associated Outcomes and Resource Utilization Among Older ICU Patients With Suspected Infection  Journal Articles
• Frailty and Bleeding in Older Adults Undergoing TAVR or SAVR  Journal Articles
• Frailty and Life-Space Mobility: Implications for Clinical Practice and Research  Journal Articles
• Frailty and Risk of Fractures in Patients With Type 2 Diabetes  Journal Articles
• Frailty and Risk of Fractures in Patients with Rheumatoid Arthritis: Data from the Ontario Best Practices Research Initiative (OBRI)  Conferences
• Frailty and associated outcomes and resource utilization following in-hospital cardiac arrest  Journal Articles
• Frailty and associated prognosis among older emergency department patients with suspected infection: A prospective, observational cohort study  Journal Articles
• Frailty and invasive mechanical ventilation: association with outcomes, extubation failure, and tracheostomy  Journal Articles
• Frailty and outcomes in heart failure patients from high-, middle-, and low-income countries  Journal Articles
• Frailty and risk of osteoporotic fractures in patients with rheumatoid arthritis: Data from the Ontario Best Practices Research Initiative  Journal Articles
• Frailty and survival among veterans treated with abiraterone or enzalutamide for metastatic castration-resistant prostate cancer  Journal Articles
• Frailty and survival in the 1918 influenza pandemic  Journal Articles
• Frailty and the impacts of the COVID-19 pandemic on community-living middle-aged and older adults: an analysis of data from the Canadian Longitudinal Study on Aging (CLSA)  Journal Articles
• Frailty as a Predictor of Postoperative Morbidity and Mortality Following Liver Resection  Journal Articles
• Frailty differences across population characteristics associated with health inequality: a cross-sectional analysis of baseline data from the Canadian Longitudinal Study on Aging (CLSA)  Journal Articles
• Frailty in inflammatory bowel disease: analysis of the National Inpatient Sample 2015–2019  Journal Articles
• Frailty increases mortality among patients ≥ 80 years old treated in Polish ICUs  Journal Articles
• Frailty is associated with long-term outcome in patients with sepsis who are over 80 years old: results from an observational study in 241 European ICUs  Journal Articles
• Frailty is crucial in FORECASTing outcomes in critical care  Journal Articles
• Frailty phenotype as a predictor of bleeding and mortality in ambulatory patients receiving direct oral anticoagulants  Journal Articles
• Frailty prevalence and efficient screening in primary care-based memory clinics  Journal Articles
• Frailty screening in older adults: is annual screening necessary in primary care?  Journal Articles
• Frailty to predict unplanned hospitalization, stroke, bleeding, and death in atrial fibrillation  Conferences
• Frailty, Outcomes, Recovery and Care Steps of Critically Ill Patients (FORECAST): a prospective, multi-centre, cohort study  Journal Articles
• Frailty, the Elderly, and the Guidelines on Perioperative Cardiac Risk Assessment and Management in Noncardiac Surgery  Journal Articles
• Functional Decline After Nonhospitalized Injuries in Older Patients: Results From the Canadian Emergency Team Initiative Cohort in Elders  Journal Articles
• Geriatric Assessment and Frailty Scores Predict Mortality in Myeloma: Systematic Review and Meta-analysis  Journal Articles
• Habitual Physical Activity in Older Adults Undergoing TAVR  Journal Articles
• Handgrip Strength, but Not 5‐Meter Walk, Adds Value to a Clinical Nutrition Assessment  Journal Articles
• Handgrip strength predicts length of stay and quality of life in and out of hospital  Journal Articles
• How regional versus global thresholds for physical activity and grip strength influence physical frailty prevalence and mortality estimates in PURE: a prospective multinational cohort study of community-dwelling adults  Journal Articles
• Identification of older adults with frailty in the Emergency Department using a frailty index: results from a multinational study  Journal Articles
• Identifying frailty in primary care: A systematic review  Journal Articles
• Impact of Frailty on Health Care Resource Utilization and Costs of Care in Myelodysplastic Syndromes  Journal Articles
• Impact of frailty on hiatal hernia repair: a nationwide analysis of in-hospital clinical and healthcare utilization outcomes  Journal Articles
• Impact of multimorbidity and frailty on adverse outcomes among older delayed discharge patients: Implications for healthcare policy  Journal Articles
• Incorporation of frailties into a cure rate regression model and its diagnostics and application to melanoma data  Journal Articles
• Increasing frailty is associated with higher prevalence and reduced recognition of delirium in older hospitalised inpatients: results of a multi-centre study  Journal Articles
• Individualizing the care of older heart failure patients  Journal Articles
• Integrating a Standardized Self-Report Tool into Geriatric Medicine Practice during the COVID-19 Pandemic: A Mixed-Methods Study  Journal Articles
• Intensity of outpatient physician care in the last year of life: a population-based retrospective descriptive study  Journal Articles
• Interaction Between Frailty and Access Site in Older Adults Undergoing Transcatheter Aortic Valve Replacement  Journal Articles
• Interdisciplinary staff perceptions of advance care planning in long-term care homes: a qualitative study  Journal Articles
• Interventions that have potential to help older adults living with social frailty: a systematic scoping review  Journal Articles
• Interventions to prevent or reduce the level of frailty in community-dwelling older adults: a scoping review of the literature and international policies  Journal Articles
• Interventions to prevent, delay or reverse frailty in older people: a journey towards clinical guidelines  Journal Articles
• Letter by Wong and Demers Regarding Article, “Efficacy and Safety of Dapagliflozin According to Frailty in Patients With Heart Failure: A Prespecified Analysis of the DELIVER Trial”  Journal Articles
• Machine learning for identification of frailty in Canadian primary care practices  Journal Articles
• Malnutrition or frailty? Overlap and evidence gaps in the diagnosis and treatment of frailty and malnutrition  Journal Articles
• Management and outcomes in critically ill nonagenarian versus octogenarian patients  Journal Articles
• Management of Frailty: A Systematic Review and Network Meta-analysis of Randomized Controlled Trials  Journal Articles
• Management of Non-ST-Elevation Myocardial Infarction in Elderly Patients: Time to Consider Frailty and Quality of Life  Journal Articles
• Management of frailty: a protocol of a network meta-analysis of randomized controlled trials  Journal Articles
• Mapping context of sedentary behaviour in older adults who are prefrail and frail: an analysis of secondary outcomes from a longitudinal study (MAPS-B).  Journal Articles
• Measuring frailty in clinical practice: a comparison of physical frailty assessment methods in a geriatric out-patient clinic  Journal Articles
• Modified frailty index predicts postoperative morbidity in adhesive small bowel obstruction: analyzing the National Inpatient Sample 2015-2019  Journal Articles
• Modifying the Phenotypic Frailty Model in Predicting Risk of Major Osteoporotic Fracture in the Elderly  Journal Articles
• MoveStrong at home: a feasibility study of a model for remote delivery of functional strength and balance training combined with nutrition education for older pre-frail and frail adults  Journal Articles
• Noninvasive ventilation in COVID-19 patients aged ≥ 70 years—a prospective multicentre cohort study  Journal Articles
• Nutrition and Physical Activity Clinical Practice Guidelines for Older Adults Living with Frailty  Journal Articles
• Nutrition support in cardiac surgery patients: Be calm and feed on!  Journal Articles
• Optimizing care for critically ill older adults  Journal Articles
• Oral Health in Healthy Aging  Journal Articles
• Oral Health, Diet, and Frailty at Baseline of the Canadian Longitudinal Study on Aging  Journal Articles
• Osteoporotic fractures and obesity affect frailty progression: a longitudinal analysis of the Canadian multicentre osteoporosis study  Journal Articles
• PROCEEDINGS OF THE CANADIAN FRAILTY NETWORK WORKSHOP: IDENTIFYING BIOMARKERS OF FRAILTY TO SUPPORT FRAILTY RISK ASSESSMENT, DIAGNOSIS AND PROGNOSIS. TORONTO, JANUARY 15, 2018  Journal Articles
• Perspectives of older adults, caregivers, and healthcare providers on frailty screening: a qualitative study  Journal Articles
• Phosphate is associated with frailty in older patients with chronic kidney disease not on dialysis  Journal Articles
• Physical Frailty: ICFSR International Clinical Practice Guidelines for Identification and Management  Journal Articles
• Physical Function and Frailty for Predicting Adverse Outcomes in Older Primary Care Patients  Journal Articles
• Physical frailty and survival time after the onset of functional disability: Is there a sex difference?  Journal Articles
• Place of Care Trajectories in the Last Two Weeks of Life: A Population-Based Cohort Study of Ontario Decedents  Journal Articles
• Post Hoc Analyses of a Randomized Controlled Trial for the Effect of Pharmacist Deprescribing Intervention on the Anticholinergic Burden in Frail Community-Dwelling Older Adults  Journal Articles
• Prevalence and prognostic impact of physical frailty in interstitial lung disease: A prospective cohort study  Journal Articles
• Prevalence of Frailty in Patients Referred to the Kidney Transplant Waitlist  Journal Articles
• Prevalence of geriatric impairments and frailty categorization among real-world patients with multiple myeloma: a prospective cohort study (MFRAIL)  Journal Articles
• Prevalence, Incidence, and Predictors of Self-reported Swallowing Difficulties in Community-Dwelling Adults: A Population-Based Study from the Canadian Longitudinal Study on Aging (CLSA)  Journal Articles
• Prognostic Association Between Frailty and Post-Arrest Health Outcomes in Patients Receiving Home Care: A Population-Based Retrospective Cohort Study  Journal Articles
• Prognostic association of frailty with post-arrest outcomes following cardiac arrest: A systematic review and meta-analysis  Journal Articles
• Protein and Exercise to Reverse Frailty in Older Men and Women Undergoing Transcatheter Aortic Valve Replacement: Design of the PERFORM-TAVR Trial  Journal Articles
• Recommendations for the pharmacological treatment of treatment-resistant depression: A systematic review protocol  Journal Articles
• Relation of Frailty to Outcomes in Patients With Acute Coronary Syndromes  Journal Articles
• Relationship Between Obesity and Risk of Major Osteoporotic Fracture in Postmenopausal Women: Taking Frailty Into Consideration  Journal Articles
• Relationship between the Clinical Frailty Scale and short-term mortality in patients ≥ 80 years old acutely admitted to the ICU: a prospective cohort study  Journal Articles
• Respiratory Symptoms Are Associated With Frailty in Older Adults With Normal Spirometry, Independent of Smoking, in the Canadian Longitudinal Study of Aging  Journal Articles
• Retention in RCTs of physical rehabilitation for adults with frailty: a systematic review and meta-analysis  Journal Articles
• Revised 15-item MDS-specific frailty scale maintains prognostic potential  Journal Articles
• Sex-Specific Determinants of Outcomes After Transcatheter Aortic Valve Replacement  Journal Articles
• Sex-specific treatment characteristics and 30-day mortality outcomes of critically ill COVID-19 patients over 70 years of age—results from the prospective COVIP study  Journal Articles
• Simplified frailty assessment tools: are we really capturing frailty or something else?  Journal Articles
• Single nuclei profiling identifies cell specific markers of skeletal muscle aging, frailty, and senescence  Journal Articles
• Sleep Disturbance in Older Patients in the Emergency Department: Prevalence, Predictors and Associated Outcomes  Journal Articles
• State of the Science Burn Research: Burns in the Elderly  Journal Articles
• Statistical Significance in Trauma Research: Too Unstable to Trust?  Journal Articles
• Strategies for working across Canadian practice-based research and learning networks (PBRLNs) in primary care: focus on frailty  Journal Articles
• Supplement-based nutritional strategies to tackle frailty: A multifactorial, double-blind, randomized placebo-controlled trial  Journal Articles
• The Association Between Frailty and a Nurse-Identified Need for Comprehensive Geriatric Assessment Referral from the Emergency Department  Journal Articles
• The Association Between Shift Work Exposure and Frailty Among Middle-Aged and Older Adults  Journal Articles
• The Association between Frailty and Short-Term Outcomes in an Intensive Care Unit Rehabilitation Trial: An Exploratory Analysis  Journal Articles
• The C5-75 Program: Meeting the Need for Efficient, Pragmatic Frailty Screening and Management in Primary Care  Journal Articles
• The Clinical Frailty Scale for Risk Stratification in Patients With Fibrotic Interstitial Lung Disease  Journal Articles
• The Diagnostic Accuracy and Clinimetric Properties of Screening Instruments to Identify Frail Older Adults Attending Emergency Departments: A Protocol for a Mixed Methods Systematic Review and Meta-Analysis  Journal Articles
• The Drug Burden Index and Level of Frailty as Determinants of Healthcare Costs in a Cohort of Older Frail Adults in New Zealand  Journal Articles
• The Hospital Frailty Risk Score and its association with in-hospital mortality, cost, length of stay and discharge location in patients with heart failure short running title: Frailty and outcomes in heart failure  Journal Articles
• The ICM research agenda on intensive care unit-acquired weakness  Journal Articles
• The Patterns, Risk Factors, and Prediction of Progression in Chronic Kidney Disease: A Narrative Review  Journal Articles
• The Short Performance Physical Battery Is Associated with One-Year Emergency Department Visits and Hospitalization  Journal Articles
• The association between frailty, long-term care home characteristics and COVID-19 mortality before and after SARS-CoV-2 vaccination: a retrospective cohort study  Journal Articles
• The association between patients’ frailty status, multimorbidity, and demographic characteristics and changes in primary care for chronic conditions during the COVID-19 pandemic: a pre-post study  Journal Articles
• The association between preoperative modified frailty index and postoperative complications in Chinese elderly patients with hip fractures  Journal Articles
• The contribution of frailty, cognition, activity of daily life and comorbidities on outcome in acutely admitted patients over 80 years in European ICUs: the VIP2 study  Journal Articles
• The cumulative effect of frailty and cognition on mortality – results of a prospective cohort study  Journal Articles
• The five-factor modified frailty index predicts adverse postoperative and chemotherapy outcomes in gynecologic oncology  Journal Articles
• The impact of frailty on ICU and 30-day mortality and the level of care in very elderly patients (≥ 80 years)  Journal Articles
• The impact of frailty on survival in elderly intensive care patients with COVID-19: the COVIP study  Journal Articles
• The modified frailty index predicts postoperative morbidity in elective hernia repair patients: analysis of the national inpatient sample 2015–2019  Journal Articles
• The prevalence and outcomes of frail older adults in clinical trials in multiple myeloma: A Systematic Review  Conferences
• The prognostic significance of frailty compared to peak oxygen consumption and B‐type natriuretic peptide in patients with advanced heart failure  Journal Articles
• Time-dependent uncertainty of critical care transitions in very old patients - lessons for time-limited trials  Journal Articles
• Timed Up and Go predicts functional decline in older patients presenting to the emergency department following minor trauma  Journal Articles
• Transforming primary care for older Canadians living with frailty: mixed methods study protocol for a complex primary care intervention  Journal Articles
• Transplant-ineligible newly diagnosed multiple myeloma: Current and future approaches to clinical care: A Young International Society of Geriatric Oncology Review Paper  Journal Articles
• Triaging Access to Critical Care Resources in Patients With Chronic Respiratory Diseases in the Event of a Major COVID-19 Surge  Journal Articles
• Understanding Aging, Frailty, and Resilience in Ontario First Nations  Journal Articles
• Understanding frailty: a qualitative study of European healthcare policy-makers’ approaches to frailty screening and management  Journal Articles
• Vaccine Effectiveness of non-adjuvanted and adjuvanted trivalent inactivated influenza vaccines in the prevention of influenza-related hospitalization in older adults: A pooled analysis from the Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN)  Journal Articles
• Wellness in the Face of Frailty Among Older Adults in First Nations Communities  Journal Articles
• Yes, Frailty Matters: Time for Action  Journal Articles