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Journal article

Recommendations for the pharmacological treatment of treatment-resistant depression: A systematic review protocol

Abstract

INTRODUCTION: Depression is a serious and widespread mental health disorder. Although effective treatment does exist, a significant proportion of patients with depression fail to respond to antidepressant treatment trials, a condition named treatment-resistant depression. Efficient approach should be given this condition in order to revert the burden caused by depression. Clinical practice guidelines (CPGs) are evidence-based health promotion …

Authors

Gabriel FC; Stein AT; de Melo DO; Fontes-Mota GCH; dos Santos IB; da Silva Rodrigues C; Rodrigues MC; Fráguas R; Florez ID; Correia DT

Journal

PLOS ONE, Vol. 17, No. 4,

Publisher

Public Library of Science (PLoS)

DOI

10.1371/journal.pone.0267323

ISSN

1932-6203