Drug Screening Assays, Antitumor Concept

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• A New Series of Succinimido-ferrociphenols and Related Heterocyclic Species Induce Strong Antiproliferative Effects, Especially against Ovarian Cancer Cells Resistant to Cisplatin  Journal Articles
• A New Strategy To Improve the Metabolic Stability of Lactone: Discovery of (20S,21S)-21-Fluorocamptothecins as Novel, Hydrolytically Stable Topoisomerase I Inhibitors  Journal Articles
• Agave negatively regulates YAP and TAZ transcriptionally and post-translationally in osteosarcoma cell lines  Journal Articles
• Anti-proliferative and chemosensitizing effects of luteolin on human gastric cancer AGS cell line  Journal Articles
• Antibiotic and Antimalarial Quinones from Fungus-Growing Ant-Associated Pseudonocardia sp.  Journal Articles
• Antineoplastic Agents 491.¹ Synthetic Conversion of Aaptamine to Isoaaptamine, 9-Demethylaaptamine, and 4-Methylaaptamine  Journal Articles
• Antineoplastic Agents. 362. Isolation and X-ray Crystal Structure of Dibromophakellstatin from the Indian Ocean Sponge Phakellia mauritiana  Journal Articles
• Antineoplastic Agents. 380. Isolation and X-ray Crystal Structure Determination of Isoaaptamine from the Republic of Singapore Hymeniacidon sp. and Conversion to the Phosphate Prodrug Hystatin 1  Journal Articles
• Antitumor effects of a refined polysaccharide peptide fraction isolated from Coriolus versicolor: in vitro and in vivo studies.  Journal Articles
• Biochip arrays for the discovery of a biomarker surrogate in a phase I/II study assessing a novel anti-metastasis agent  Journal Articles
• Characterization of the Isosteroidal Alkaloid Chuanbeinone from Bulbus of Fritillaria pallidiflora as Novel Antitumor Agent In Vitro and In Vivo.  Journal Articles
• Design, synthesis and biological activity of piperlongumine derivatives as selective anticancer agents  Journal Articles
• Discovery of HDAC6-Selective Inhibitor NN-390 with in Vitro Efficacy in Group 3 Medulloblastoma  Journal Articles
• Enantioselective Synthesis of Planar Chiral Ferrocifens that Show Chiral Discrimination in Antiproliferative Activity on Breast Cancer Cells  Journal Articles
• Evaluation of synthetic coumarins for antiausterity cytotoxicity against pancreatic cancers  Journal Articles
• Human Cytochrome P450 Liability Studies of trans-Dihydronarciclasine: A Readily Available, Potent, and Selective Cancer Cell Growth Inhibitor  Journal Articles
• Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells  Journal Articles
• Identification of Small Molecules that Sensitize Resistant Tumor Cells to Tumor Necrosis Factor-Family Death Receptors  Journal Articles
• In vitro analysis of the herbal compound Essiac.  Journal Articles
• In vitro and in vivo antitumor activity of Bulbus Fritillariae Cirrhosae and preliminary investigation of its mechanism.  Journal Articles
• Leukemia targeting ligands isolated from phage display peptide libraries  Journal Articles
• Patient‐Derived Organoids as Therapy Screening Platforms in Cancer Patients  Journal Articles
• Structure-activity studies on the lycorine pharmacophore: A potent inducer of apoptosis in human leukemia cells  Journal Articles
• Studies directed towards the refinement of the pancratistatin cytotoxic pharmacophore  Journal Articles
• Synthesis and Biological Evaluation of Fully Functionalized seco-Pancratistatin Analogues  Journal Articles
• Synthesis and Evaluation of Anticancer Natural Product Analogues Based on Angelmarin: Targeting the Tolerance towards Nutrient Deprivation  Journal Articles
• Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide  Journal Articles
• Synthesis and evaluation of new salicylaldehyde-2-picolinylhydrazone Schiff base compounds of Ru(II), Rh(III) and Ir(III) as in vitro antitumor, antibacterial and fluorescence imaging agents  Journal Articles
• The Effect of Radiation and Cytotoxic Platinum Compounds on the Growth of Normal and Tumour Bladder Explant Cultures  Journal Articles
• The disruption of the protein complex mutantp53/p73 increases selectively the response of tumor cells to anticancer drugs  Journal Articles
• The effect of lonidamine alone and in combination with cisplatin on in vitro growth and viability of lung squamous cell carcinoma cell lines.  Journal Articles
• The histone deacetylase inhibitor valproic acid alters sensitivity towards all trans retinoic acid in acute myeloblastic leukemia cells  Journal Articles
• The in vitro effects of lonidamine combined with cisplatin in human small cell lung cancer cell lines.  Journal Articles