Cell Hypoxia Concept

subject area of

• A combination of MSH2 DNA mismatch repair deficiency and expression of the SV40 large T antigen results in cisplatin resistance of mouse embryonic fibroblasts  Journal Articles
• A novel O2-sensing mechanism in rat glossopharyngeal neurones mediated by a halothane-inhibitable background K+ conductance  Journal Articles
• A rotenone-sensitive site and H2O2 are key components of hypoxia-sensing in neonatal rat adrenomedullary chromaffin cells  Journal Articles
• Acetylcholine contributes to hypoxic chemotransmission in co-cultures of rat type 1 cells and petrosal neurons  Journal Articles
• Acute Hypoxic Regulation of Recombinant THIK-1 Stably Expressed in HEK293 Cells  Journal Articles
• Anemia increases the risk of renal cortical and medullary hypoxia during cardiopulmonary bypass  Journal Articles
• Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels  Journal Articles
• Calculation of Cellular Oxygen Concentration for Photodynamic Therapy In Vitro  Journal Articles
• Carotid Body Adaptation to Hypoxia: Cellular and Molecular Mechanisms in vitro  Journal Articles
• Carotid body chemoreceptors in dissociated cell culture  Journal Articles
• Characterization of Membrane Currents in Pulmonary Neuroepithelial Bodies: Hypoxia-Sensitive Airway Chemoreceptors  Journal Articles
• Che-1 sustains hypoxic response of colorectal cancer cells by affecting Hif-1α stabilization  Journal Articles
• Chronic Nicotine Blunts Hypoxic Sensitivity in Perinatal Rat Adrenal Chromaffin Cells via Upregulation of K_ATPChannels: Role of α7 Nicotinic Acetylcholine Receptor and Hypoxia-Inducible Factor-2α  Journal Articles
• Chronic exposure of neonatal rat adrenomedullary chromaffin cells to opioids in vitro blunts both hypoxia and hypercapnia chemosensitivity  Journal Articles
• Chronic hypoxia in vitro increases volume of dissociated carotid body chemoreceptors  Journal Articles
• Chronic hypoxia promotes an aggressive phenotype in rat prostate cancer cells  Journal Articles
• Chronic opioids regulate K_ATP channel subunit Kir6.2 and carbonic anhydrase I and II expression in rat adrenal chromaffin cells via HIF-2α and protein kinase A  Journal Articles
• Co-Cultures of Rat Petrosal Neurons and Carotid Body Type 1 Cells  Journal Articles
• Conditioned medium from hypoxia-treated adipocytes renders muscle cells insulin resistant  Journal Articles
• Co‐release of ATP and ACh mediates hypoxic signalling at rat carotid body chemoreceptors  Journal Articles
• Detection of hypoxia-evoked ATP release from chemoreceptor cells of the rat carotid body  Journal Articles
• Developmental regulation of O 2 sensing in neonatal adrenal chromaffin cells from wild-type and NADPH-oxidase-deficient mice  Journal Articles
• Divergent roles of reactive oxygen species in the responses of perinatal adrenal chromaffin cells to hypoxic challenges  Journal Articles
• Does endogenous 5-HT mediate spontaneous rhythmic activity in chemoreceptor clusters of rat carotid body?  Journal Articles
• Dopaminergic Properties of Cultured Rat Carotid Body Chemoreceptors Grown in Normoxic and Hypoxic Environments  Journal Articles
• Effects of Chemosensory Stimulation Membrane Currents Recorded with the Perforated-Patch Method from Cultured Rat Glomus Cells  Journal Articles
• Effects of Hypoxia on Cultured Chemoreceptors of the Rat Carotid Body: DNA Synthesis and Mitotic Activity in Glomus Cells  Journal Articles
• Effects of chemostimuli on [Ca²⁺]_i responses of rat aortic body type I cells and endogenous local neurons: comparison with carotid body cells  Journal Articles
• Effects of geldanamycin on HIF-1α mediated angiogenesis and invasion in prostate cancer cells  Journal Articles
• Endothelial NOS, estrogen receptor β, and HIFs cooperate in the activation of a prognostic transcriptional pattern in aggressive human prostate cancer  Journal Articles
• Enhanced BDNF signalling following chronic hypoxia potentiates catecholamine release from cultured rat adrenal chromaffin cells  Journal Articles
• Enhanced adenosine A_2b receptor signaling facilitates stimulus-induced catecholamine secretion in chronically hypoxic carotid body type I cells  Journal Articles
• Expression of functional purinergic receptors in pulmonary neuroepithelial bodies and their role in hypoxia chemotransmission  Conferences
• Expression of hypoxia inducible factor–dependent neuropeptide Y receptors Y1 and Y5 sensitizes hypoxic cells to NPY stimulation  Journal Articles
• Extracellular Signal-Regulated Kinase 2 and CHOP Restrict the Expression of the Growth Arrest-Specific p20K Lipocalin Gene to G₀  Journal Articles
• Functional mitochondria are required for O₂ but not CO₂ sensing in immortalized adrenomedullary chromaffin cells  Journal Articles
• Gill paracellular permeability and the osmorespiratory compromise during exercise in the hypoxia-tolerant Amazonian oscar (Astronotus ocellatus)  Journal Articles
• HIF-1α/FOXO1 axis regulated autophagy is protective for β cell survival under hypoxia in human islets  Journal Articles
• Heterogeneity of polarographic oxygen tension measurements in cervix cancer: An evaluation of within and between tumor variability, probe position, and track depth  Journal Articles
• High Glucose Up-regulates ADAM17 through HIF-1α in Mesangial Cells  Journal Articles
• HuR drives lung fibroblast differentiation but not metabolic reprogramming in response to TGF-β and hypoxia  Journal Articles
• Hypoxia-Driven Immune Escape in the Tumor Microenvironment  Journal Articles
• Hypoxia-induced autophagy, epithelial to mesenchymal transition, and invasion in the pathophysiology of endometriosis: a perspective  Journal Articles
• Hypoxia-inducible factor-1α mediates the expression of mature β cell-disallowed genes in hypoxia-induced β cell dedifferentiation  Journal Articles
• Hypoxia‐inducible factor‐1α in non small cell lung cancer: Relation to growth factor, protease and apoptosis pathways  Journal Articles
• Induction of HIF-2α is dependent on mitochondrial O₂ consumption in an O₂-sensitive adrenomedullary chromaffin cell line  Journal Articles
• Interstitial fluid pressure in cervical carcinoma  Conferences
• Long-term modulation of inward currents in O2 chemoreceptors by chronic hypoxia and cyclic AMP in vitro  Journal Articles
• Low glucose sensitivity and polymodal chemosensing in neonatal rat adrenomedullary chromaffin cells  Journal Articles
• Mammalian target of rapamycin complex 1 activation sensitizes human glioma cells to hypoxia-induced cell death  Journal Articles
• Mechanism and non-mechanism based imaging biomarkers for assessing biological response to treatment in non-small cell lung cancer  Journal Articles
• Mechanisms of cytosolic targeting of matrix metalloproteinase‐2  Journal Articles
• Metformin elicits anticancer effects through the sequential modulation of DICER and c-MYC  Journal Articles
• Methylation-dependent regulation of hypoxia inducible factor-1 alpha gene expression by the transcription factor Kaiso  Journal Articles
• Microenvironmental influence on macrophage regulation of angiogenesis in wounds and malignant tumors  Journal Articles
• Mitochondrial bioenergetics of astrocytes in Fragile X syndrome: new perspectives on culture conditions and sex effects  Journal Articles
• NADPH oxidase is an O ₂ sensor in airway chemoreceptors: Evidence from K ⁺ current modulation in wild-type and oxidase-deficient mice  Journal Articles
• O2-Chemosensitivity in Developing Rat Adrenal Chromaffin Cells  Journal Articles
• O₂−sensitive K⁺ channels in immortalised rat chromaffin‐cell‐derived MAH cells  Journal Articles
• Obesity during pregnancy results in maternal intestinal inflammation, placental hypoxia, and alters fetal glucose metabolism at mid-gestation  Journal Articles
• Ontogeny of O2 and CO2//H+ chemosensitivity in adrenal chromaffin cells: role of innervation  Journal Articles
• Oxygen sensing in airway chemoreceptors  Journal Articles
• Oxygenation predicts radiation response and survival in patients with cervix cancer  Journal Articles
• P2Y₂ Receptor Up-Regulation Induced by Guanosine or UTP in Rat Brain Cultured Astrocytes  Journal Articles
• Photobleaching kinetics, photoproduct formation, and dose estimation during ALA induced PpIX PDT of MLL cells under well oxygenated and hypoxic conditions  Journal Articles
• Plasticity in Cultured Arterial Chemoreceptors: Effects of Chronic Hypoxia and Cyclic AMP Analogs  Journal Articles
• Plasticity in cultured carotid body chemoreceptors: Environmental modulation of GAP‐43 and neurofilament  Journal Articles
• Postsynaptic action of GABA in modulating sensory transmission in co‐cultures of rat carotid body via GABA_A receptors  Journal Articles
• Potential Role of Mitochondria in Hypoxia Sensing by Adrenomedullary Chromaffin Cells  Conferences
• Prevalence and characteristics of hypoxic hepatitis in the largest single-centre cohort of avian influenza A(H7N9) virus-infected patients with severe liver impairment in the intensive care unit  Journal Articles
• Radiotherapy and the potential exploitation of bystander effects  Journal Articles
• Rapamycin inhibits transforming growth factor β‐induced peritoneal angiogenesis by blocking the secondary hypoxic response  Journal Articles
• Rat cultured astrocytes release guanine‐based purines in basal conditions and after hypoxia/hypoglycemia  Journal Articles
• Regulation of Oxygen Sensitivity in Adrenal Chromaffin Cells  Journal Articles
• Regulation of gill transcellular permeability and renal function during acute hypoxia in the Amazonian oscar (Astronotus ocellatus): new angles to the osmorespiratory compromise  Journal Articles
• Role of Acetylcholine Receptors and Dopamine Transporter in Regulation of Extracellular Dopamine in Rat Carotid Body Cultures Grown in Chronic Hypoxia or Nicotine  Journal Articles
• Role of Basic FGF and Oxygen in Control of Proliferation, Survival, and Neuronal Differentiation in Carotid Body Chromaffin Cells  Journal Articles
• Skeletal Muscle Erythropoietin Expression Is Responsive to Hypoxia and Exercise  Journal Articles
• Synapse Formation and Hypoxic Signalling in Co‐Cultures of Rat Petrosal Neurones and Carotid Body Type 1 Cells  Journal Articles
• Tumor factors predictive of response to hypofractionated radiotherapy in a randomized trial following breast conserving therapy  Journal Articles
• USP22 promotes hypoxia-induced hepatocellular carcinoma stemness by a HIF1α/USP22 positive feedback loop upon TP53 inactivation  Journal Articles
• Upregulation of Krebs cycle and anaerobic glycolysis activity early after onset of liver ischemia  Journal Articles
• Whole-cell currents in two subpopulations of cultured rat petrosal neurons with different tetrodotoxin sensitivities  Journal Articles