Amyotrophic Lateral Sclerosis Concept

subject area of

• 50bp deletion in the promoter for superoxide dismutase 1 (SOD1) reduces SOD1 expression in vitro and may correlate with increased age of onset of sporadic amyotrophic lateral sclerosis  Journal Articles
• A Study of the Purine Derivative AIT-082 in G93A SOD1 Transgenic Mice  Journal Articles
• A clinical trial of creatine in ALS  Journal Articles
• A genome-wide association study of sporadic ALS in a homogenous Irish population  Journal Articles
• A longitudinal study of the pathophysiological changes in single human thenar motor units in amyotrophic lateral sclerosis  Journal Articles
• A novel candidate region for ALS on chromosome 14q11.2  Journal Articles
• A phase III trial of tirasemtiv as a potential treatment for amyotrophic lateral sclerosis  Journal Articles
• ALS--decision making under uncertainty: a positive approach.  Journal Articles
• ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis  Journal Articles
• Amyotrophic Lateral Sclerosis  Journal Articles
• An Unusual Subacute Progressive Motor Neuronopathy with Myasthenia-like Features  Journal Articles
• An electrophysiological estimation of the number of motor units and rate of decay of motor units in amyotrophic lateral sclerosis.  Journal Articles
• Analysis of IFT74as a candidate gene for chromosome 9p-linked ALS-FTD  Journal Articles
• Angiogenin Levels and ANG Genotypes: Dysregulation in Amyotrophic Lateral Sclerosis  Journal Articles
• Assessing Patient Perspectives on Receiving Bad News: A Survey of 1337 Patients With Life-Changing Diagnoses  Journal Articles
• Assessing the Measurement Properties of the Self-Administered Amyotrophic Lateral Sclerosis Functional Rating Scale–Revised (ALSFRS-R): A Rasch Analysis  Journal Articles
• Assessing the psychometric properties of quality of life measures in individuals with amyotrophic lateral sclerosis: a systematic review  Journal Articles
• Association of the H63D polymorphism in the hemochromatosis gene with sporadic ALS  Journal Articles
• Author response to a Letter to the Editor entitled: Edaravone administration in pivotal clinical study 19 (Authors: Genge, Angela; Brooks, Benjamin)  Journal Articles
• Beneficial effect of ginseng root in SOD-1 (G93A) transgenic mice  Journal Articles
• Caloric Restriction Shortens Lifespan through an Increase in Lipid Peroxidation, Inflammation and Apoptosis in the G93A Mouse, an Animal Model of ALS  Journal Articles
• Caloric restriction transiently improves motor performance but hastens clinical onset of disease in the Cu/Zn‐superoxide dismutase mutant G93A mouse  Journal Articles
• Canadian best practice recommendations for the management of amyotrophic lateral sclerosis  Journal Articles
• Cerebral Tau Deposition in Comorbid Progressive Supranuclear Palsy and Amyotrophic Lateral Sclerosis: An [¹⁸F]-Flortaucipir and 7T MRI Study  Journal Articles
• Cerebrospinal fluid from patients with amyotrophic lateral sclerosis inhibits sonic hedgehog function  Journal Articles
• Childhood amyotrophic lateral sclerosis caused by excess sphingolipid synthesis  Journal Articles
• Clinicopathological features of primary lateral sclerosis are different from amyotrophic lateral sclerosis  Journal Articles
• Cognitive Deterioration and Functional Compensation in ALS Measured with fMRI Using an Inhibitory Task  Journal Articles
• Control of Motoneuron Survival by Angiogenin  Journal Articles
• Creatine supplementation and riluzole treatment provide similar beneficial effects in copper, zinc superoxide dismutase (G93A) transgenic mice  Journal Articles
• Crosstalk between Notch and Sonic hedgehog signaling in a mouse model of amyotrophic lateral sclerosis  Journal Articles
• Effects of age, temperature, and disease on the refractoriness of human nerve and muscle.  Journal Articles
• Effects of high‐intensity endurance exercise training in the G93A mouse model of amyotrophic lateral sclerosis  Journal Articles
• Elevated serum angiogenin levels in ALS  Journal Articles
• Evaluation of the Golgi trafficking protein VPS54 (wobbler) as a candidate for ALS  Journal Articles
• Functional compensation in partially denervated muscles  Journal Articles
• Functional compensation of human motor units in health and disease  Journal Articles
• Genetic testing for amyotrophic lateral sclerosis in Canada – an assessment of current practices  Journal Articles
• Heterozygous frameshift variants in HNRNPA2B1 cause early-onset oculopharyngeal muscular dystrophy  Journal Articles
• Human motor units in health and disease  Journal Articles
• Impact of Treadmill Running and Sex on Hippocampal Neurogenesis in the Mouse Model of Amyotrophic Lateral Sclerosis  Journal Articles
• Innate immunity in amyotrophic lateral sclerosis  Journal Articles
• Intentions of Canadian health professionals towards recommending exercise for people living with ALS  Journal Articles
• Is edaravone harmful? (A placebo is not a control)  Journal Articles
• Lack of Effect of Methylene Blue in the SOD1 G93A Mouse Model of Amyotrophic Lateral Sclerosis  Journal Articles
• Lasting impact in families after death from ALS  Journal Articles
• MN-166 (ibudilast) in Amyotrophic Lateral Sclerosis in a Phase IIb/III Study: COMBAT-ALS Study Design  Journal Articles
• MOTONEURONE DISEASE AND AGEING  Journal Articles
• Manganese Superoxide Dismutase Levels Are Elevated in a Proportion of Amyotrophic Lateral Sclerosis Patient Cell Lines  Journal Articles
• Methods for Estimating the Numbers of Motor Units in Human Muscles  Journal Articles
• Motor unit estimates in the biceps‐brachialis in amyotrophic lateral sclerosis  Journal Articles
• Motor unit estimations in small muscles of the hand  Journal Articles
• Motor‐evoked responses in primary lateral sclerosis  Journal Articles
• Neuropsychiatric Symptom Burden across Neurodegenerative Disorders and its Association with Function  Journal Articles
• One Universal Common Endpoint in Mouse Models of Amyotrophic Lateral Sclerosis  Journal Articles
• PRIMARY LATERAL SCLEROSIS: CLINICAL FEATURES, NEUROPATHOLOGY AND DIAGNOSTIC CRITERIA  Journal Articles
• Paraoxonase promoter and intronic variants modify risk of sporadic amyotrophic lateral sclerosis  Journal Articles
• Pathological laughing and crying in amyotrophic lateral sclerosis: an association with prefrontal cognitive dysfunction  Journal Articles
• Phase II/III randomized trial of TCH346 in patients with ALS  Journal Articles
• Plasma exchange with albumin replacement and disease progression in amyotrophic lateral sclerosis: a pilot study  Journal Articles
• Progranulin mutations and amyotrophic lateral sclerosis or amyotrophic lateral sclerosis-frontotemporal dementia phenotypes  Journal Articles
• Reappraisal of an ALS trial: unaccounted procedural risk  Journal Articles
• Refining items for a preference-based, amyotrophic lateral sclerosis specific, health-related quality of life scale  Journal Articles
• Reviewing the evidence for viruses as environmental risk factors for ALS: A new perspective  Journal Articles
• SUBCUTANEOUS IGF-1 IS NOT BENEFICIAL IN 2-YEAR ALS TRIAL  Journal Articles
• Safety and efficacy of oral levosimendan in people with amyotrophic lateral sclerosis (the REFALS study): a randomised, double-blind, placebo-controlled phase 3 trial  Journal Articles
• Screening of hypoxia-inducible genes in sporadic ALS  Journal Articles
• Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis  Journal Articles
• Sodium Phenylbutyrate–Taurursodiol for ALS  Journal Articles
• Sonic Hedgehog is Cytoprotective against Oxidative Challenge in a Cellular Model of Amyotrophic Lateral Sclerosis  Journal Articles
• TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis  Journal Articles
• Targeting cellular energy production in neurological disorders  Journal Articles
• Targeting cellular energy production in neurological disorders.  Journal Articles
• The complement factor C5a receptor is upregulated in NFL−/− mouse motor neurons  Journal Articles
• The complex genetics of amyotrophic lateral sclerosis  Journal Articles
• The extent and time course of motoneuron involvement in amyotrophic lateral sclerosis  Journal Articles
• The impact of rehabilitative interventions on quality of life: a qualitative evidence synthesis of personal experiences of individuals with amyotrophic lateral sclerosis  Journal Articles
• Transient caloric restriction in early adulthood hastens disease endpoint in male, but not female, Cu/Zn‐SOD mutant G93A mice  Journal Articles
• Trophic and proliferative effects of Shh on motor neurons in embryonic spinal cord culture from wildtype and G93A SOD1 mice  Journal Articles
• Variation of Phenotype in Charcot-Marie-Tooth Disease  Journal Articles
• Why is ALS so Difficult to Treat?  Journal Articles