Journal article
Pathological laughing and crying in amyotrophic lateral sclerosis: an association with prefrontal cognitive dysfunction
Abstract
Pathological laughing and crying (PLC) frequently occurs in amyotrophic lateral sclerosis (ALS). The etiology of the syndrome is unclear, but frontal-subcortical circuits are implicated, given their known association with mood and affect regulation. Ten ALS patients with PLC, eight patients without, and ten healthy controls were compared on a number of psychometric measures. Three indices of prefrontal cortical function were given: the …
Authors
McCullagh S; Moore M; Gawel M; Feinstein A
Journal
Journal of the Neurological Sciences, Vol. 169, No. 1-2, pp. 43–48
Publisher
Elsevier
Publication Date
October 1999
DOI
10.1016/s0022-510x(99)00214-2
ISSN
0022-510X