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- A combination of MSH2 DNA mismatch repair deficiency and expression of the SV40 large T antigen results in cisplatin resistance of mouse embryonic fibroblasts Academic Article
- A double recombinant adenovirus expressing the costimulatory molecule B7-1 (murine) and human IL-2 induces complete tumor regression in a murine breast adenocarcinoma model. Academic Article
- A transgenic mouse line harboring a smooth muscle alpha-actin promoter polyomavirus middle T antigen transgene develops an epithelial hyperplasia in the rectum and distal stomach. Academic Article
- Activation of polyomavirus DNA replication by yeast GAL4 is dependent on its transcriptional activation domains. Academic Article
- At the onset of transformation polyomavirus middle-T recruits shc and src to a perinuclear compartment coincident with condensation of endosomes Academic Article
- Combined Treatment of a Murine Breast Cancer Model with Type 5 Adenovirus Vectors Expressing Murine Angiostatin and IL-12: A Role for Combined Anti-Angiogenesis and Immunotherapy Academic Article
- Construction of a helper-free recombinant adenovirus that expresses polyomavirus large T antigen. Academic Article
- Determination of the origin-specific DNA-binding domain of polyomavirus large T antigen Academic Article
- Estradiol Promotes Growth and Angiogenesis in Polyoma Middle T Transgenic Mouse Mammary Tumor Explants Academic Article
- Estradiol increases extracellular levels of vascular endothelial growth factorin vivo in murine mammary cancer Academic Article
- Evidence for Multiple Mechanisms for Membrane Binding and Integration via Carboxyl-Terminal Insertion Sequences† Academic Article
- Expression of SV40 large T antigen, but not small t antigen, is required for the induction of chromosomal aberrations in transformed human cells Academic Article
- Functional implications of mutations within polyomavirus large T antigen Rb-binding domain: effects on pRb and p107 binding in vitro and immortalization activity in vivo Academic Article
- Induction of genomic instability in SV40 transformed human cells: sufficiency of the N-terminal 147 amino acids of large T antigen and role of pRB and p53. Academic Article
- Insulin-like Growth Factor II Signaling in Neoplastic Proliferation Is Blocked by Transgenic Expression of the Metalloproteinase Inhibitor Timp-1 Academic Article
- Large T antigens of many polyomaviruses are able to form complexes with the retinoblastoma protein Academic Article
- Overproduction of polyomavirus middle T antigen in mammalian cells through the use of an adenovirus vector Academic Article
- PEA3 is overexpressed in mouse metastatic mammary adenocarcinomas. Academic Article
- Polyomavirus and simian virus 40 large T antigens bind to common DNA sequences Academic Article
- Polyomavirus large T-antigen binds the ‘pRb related’ protein p130 through sequences in conserved region 2 Academic Article
- Requirement for Both Shc and Phosphatidylinositol 3′ Kinase Signaling Pathways in Polyomavirus Middle T-Mediated Mammary Tumorigenesis Academic Article
- Requirements for species-specific papovavirus DNA replication Academic Article
- Reversion of middle T antigen-transformed Rat-2 cells by Krev-1: implications for the role of p21c-ras in polyomavirus-mediated transformation. Academic Article
- Simultaneous overexpression of avian pp60c-src and polyomavirus middle T antigen in mammalian cells Academic Article
- The amino terminus of polyomavirus middle T antigen is required for transformation Academic Article
- The breast tumor microenvironment alters the phenotype and function of natural killer cells Academic Article
- The major site of tyrosine phosphorylation in polyomavirus middle T antigen is not required for transformation Academic Article
- Tissue specificity of oncogene action: endothelial cell tumours in polyoma middle T transgenic mice. Academic Article
- Tumour therapy in mice using adenovirus vectors expressing human TNFa. Academic Article