Influenza virus H1N1 activates platelets through FcγRIIA signaling and thrombin generation Academic Article uri icon

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abstract

  • Key PointsIn influenza-immune subjects, H1N1 influenza virus–containing immune complexes can activate platelets through FcγRIIA. H1N1 can also activate platelets through thrombin, independently of FcγRIIA, pointing to a role of coagulation in influenza infection.

authors

  • Boilard, Eric
  • Pare, Guillaume
  • Rousseau, Matthieu
  • Cloutier, Nathalie
  • Dubuc, Isabelle
  • Lévesque, Tania
  • Borgeat, Pierre
  • Flamand, Louis

publication date

  • May 1, 2014

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