Journal article
Effect of deoxynivalenol on the porcine acquired immune response and potential remediation by a novel modified HSCAS adsorbent
Abstract
The objective of this study was to determine the immunotoxic effects of deoxynivalenol (DON) in weaning piglets, and potential efficacy of a modified hydrated sodium calcium aluminosilicate (HSCAS) adsorbent to reduce DON toxicity. Four groups of 21-day-old male piglets (n = 7/group) were fed a control diet or diet containing 1.0 or 3.0 mg DON/kg, or 3.0 mg DON/kg plus 0.05% modified HSCAS for 4 weeks. Compared to the control, the DON diets …
Authors
Zhang L; Ma R; Zhu M-X; Zhang N-Y; Liu X-L; Wang Y-W; Qin T; Zheng L-Y; Liu Q; Zhang W-P
Journal
Food and Chemical Toxicology, Vol. 138, ,
Publisher
Elsevier
Publication Date
April 2020
DOI
10.1016/j.fct.2020.111187
ISSN
0278-6915
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Adaptive ImmunityAluminum SilicatesAnimal FeedAnimalsAnimals, NewbornAntibodies, ViralAntioxidantsApoptosisCaspase 3CatalaseCircovirusCytokinesDietFood ContaminationGlutathioneMaleMalondialdehydeProto-Oncogene Proteins c-hckSpleenSuperoxide DismutaseSwineThymus GlandTrichothecenesTumor Necrosis Factor-alphaViral VaccinesWeaning