selected scholarly activity
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academic article
- Intrinsic BMP inhibitor Gremlin regulates alveolar epithelial type II cell proliferation and differentiation. Biochemical and Biophysical Research Communications. 656:53-62. 2023
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Myeloid‐specific deletion of activating transcription factor 6 alpha increases
CD11b + macrophage subpopulations and aggravates lung fibrosis. Immunology and Cell Biology. 101:412-427. 2023 - Therapeutic strategies targeting pro-fibrotic macrophages in interstitial lung disease. Biochemical Pharmacology. 211:115501-115501. 2023
- Antifibrotic Drug Nintedanib Inhibits CSF1R to Promote IL-4–associated Tissue Repair Macrophages. American Journal of Respiratory Cell and Molecular Biology. 68:366-380. 2023
- Oncolytic BHV-1 Is Sufficient to Induce Immunogenic Cell Death and Synergizes with Low-Dose Chemotherapy to Dampen Immunosuppressive T Regulatory Cells. Cancers. 15:1295-1295. 2023
- The physician factor and anatomical site in 8846 consecutive mediastinal lymph node aspirations in a cross-sectional study. Scientific Reports. 13:1784. 2023
- Circulating CD200 is increased in the secretory phase of women with endometriosis as is endometrial mRNA, and endometrial stromal cell CD200R1 is increased in spite of reduced mRNA. Early pregnancy : biology and medicine : the official journal of the Society for the Investigation of Early Pregnancy. 89:e13655. 2023
- The proteomic landscape of glioblastoma recurrence reveals novel and targetable immunoregulatory drivers. Acta Neuropathologica. 144:1127-1142. 2022
- Cigarette smoke augments CSF3 expression in neutrophils to compromise alveolar–capillary barrier function during influenza infection. European Respiratory Journal. 60:2102049-2102049. 2022
- IFNAR blockade synergizes with oncolytic VSV to prevent virus-mediated PD-L1 expression and promote antitumor T cell activity. Molecular Therapy - Oncolytics. 25:16-30. 2022
- Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia. Cell Metabolism. 34:919-936.e8. 2022
- Pan-Lysyl Oxidase Inhibitor PXS-5505 Ameliorates Multiple-Organ Fibrosis by Inhibiting Collagen Crosslinks in Rodent Models of Systemic Sclerosis. International Journal of Molecular Sciences. 23:5533-5533. 2022
- Type I interferon regulates proteolysis by macrophages to prevent immunopathology following viral infection. PLoS Pathogens. 18:e1010471-e1010471. 2022
- An Evaluation of Cardiac Health in the Spontaneously Hypertensive Rat Colony: Implications of Evolutionary Driven Increases in Concentric Hypertrophy. American Journal of Hypertension. 35:264-271. 2022
- CD200S-positive granulated lymphoid cells in endometrium appear to be CD56-positive uterine NK cells. Journal of Reproductive Immunology. 150:103477-103477. 2022
- Connective-Tissue Growth Factor Contributes to TGF-β1–induced Lung Fibrosis. American Journal of Respiratory Cell and Molecular Biology. 66:260-270. 2022
- Advanced detection strategies for cardiotropic virus infection in a cohort study of heart failure patients. Laboratory Investigation. 102:14-24. 2022
- Shroom3, a Gene Associated with CKD, Modulates Epithelial Recovery after AKI. Kidney360. 3:51-62. 2022
- The CaT stretcher: An open-source system for delivering uniaxial strain to cells and tissues (CaT). Frontiers in Bioengineering and Biotechnology. 10:959335. 2022
- Lasting Changes to Circulating Leukocytes in People with Mild SARS-CoV-2 Infections. Viruses. 13:2239-2239. 2021
- Emerging therapeutic targets for idiopathic pulmonary fibrosis: preclinical progress and therapeutic implications. Expert Opinion on Therapeutic Targets. 25:939-948. 2021
- Potentiation of long-acting β2-agonist and glucocorticoid responses in human airway epithelial cells by modulation of intracellular cAMP. Respiratory Research. 22:266. 2021
- Cell-specific drug targeting in the lung. Biochemical Pharmacology. 190:114577-114577. 2021
- Circulating fibrocytes are not disease-specific prognosticators in idiopathic pulmonary fibrosis. European Respiratory Journal. 58:2100172-2100172. 2021
- Engineered microenvironment for the study of myofibroblast mechanobiology. Wound Repair and Regeneration. 29:588-596. 2021
- Monocyte and macrophage derived myofibroblasts: Is it fate? A review of the current evidence. Wound Repair and Regeneration. 29:548-562. 2021
- A Robust Protocol for Decellularized Human Lung Bioink Generation Amenable to 2D and 3D Lung Cell Culture. Cells. 10:1538-1538. 2021
- “Expression of endocannabinoid system components in human airway epithelial cells: impact of sex and chronic respiratory disease status”. Matthew F. Fantauzzi, Jennifer A. Aguiar, Benjamin J-M. Tremblay, Michael J. Mansfield, Toyoshi Yanagihara, Abiram Chandiramohan, Spencer Revill, Min Hyung Ryu, Chris Carlsten, Kjetil Ask, Martin Stämpfli, Andrew C. Doxey and Jeremy A. Hirota. ERJ Open Res 2020; 6: 00128-2020.. ERJ Open Research. 7:50128-2020. 2021
- Activin A and Cell-Surface GRP78 Are Novel Targetable RhoA Activators for Diabetic Kidney Disease. International Journal of Molecular Sciences. 22:2839-2839. 2021
- Abstract PO052: Uncovering the evolution of Glioblastoma proteome landscape from primary to the recurrent stage for development of novel diagnostic and predictive biomarkers. Cancer Research. 81:PO052-PO052. 2021
- Mononuclear phagocytic system and fibrosis: back to the future?. European Respiratory Journal. 57:2004466-2004466. 2021
- FK506-Binding Protein 13 Expression Is Upregulated in Interstitial Lung Disease and Correlated with Clinical Severity. A Potentially Protective Role. American Journal of Respiratory Cell and Molecular Biology. 64:235-246. 2021
- Increased Monocyte-Derived CD11b+ Macrophage Subpopulations Following Cigarette Smoke Exposure Are Associated With Impaired Bleomycin-Induced Tissue Remodelling. Frontiers in Immunology. 12:740330. 2021
- Mouse Models of Lung Fibrosis. Methods in Molecular Biology. 2299:291-321. 2021
- High-intensity cycling re-warm up within a very short time-frame increases the subsequent intermittent sprint performance. European Journal of Sport Science. 20:1307-1317. 2020
- Potentiation of Long-Acting β2-Agonist and Glucocorticoid Responses in Human Airway Epithelial Cells by Modulation of Intracellular cAMP 2020
- Expression of endocannabinoid system components in human airway epithelial cells: impact of sex and chronic respiratory disease status. ERJ Open Research. 6:00128-2020. 2020
- Suboptimal treatment response to anti-IL-5 monoclonal antibodies in severe eosinophilic asthmatics with airway autoimmune phenomena. European Respiratory Journal. 56:2000117-2000117. 2020
- Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue. European Respiratory Journal. 56:2001123-2001123. 2020
- Current models of pulmonary fibrosis for future drug discovery efforts. European Journal of Sport Science. 15:931-941. 2020
- Inhalation: A means to explore and optimize nintedanib's pharmacokinetic/pharmacodynamic relationship. Pulmonary Pharmacology and Therapeutics. 63:101933-101933. 2020
- Connective-Tissue Growth Factor (CTGF/CCN2) Contributes to TGF-β1-Induced Lung Fibrosis 2020
- The importance of interventional timing in the bleomycin model of pulmonary fibrosis. European Respiratory Journal. 55:1901105-1901105. 2020
- Protein Misfolding and Endoplasmic Reticulum Stress in Chronic Lung Disease. Chest. 157:1207-1220. 2020
- Expression of the endocannabinoid system in the human airway epithelial cells – Impact of sex and chronic respiratory disease status 2020
- TACAN Is an Ion Channel Involved in Sensing Mechanical Pain. Cell. 180:956-967.e17. 2020
- ABCF1 regulates dsDNA-induced immune responses in human airway epithelial cells 2020
- ABCF1 Regulates dsDNA-induced Immune Responses in Human Airway Epithelial Cells. Frontiers in Cellular and Infection Microbiology. 10:487. 2020
- Galectin-3 levels are elevated following nintedanib treatment. Therapeutic Advances in Chronic Disease. 11:204062232096841-204062232096841. 2020
- Microbial Regulation of Enteric Eosinophils and Its Impact on Tissue Remodeling and Th2 Immunity. Frontiers in Immunology. 11:155. 2020
- Cell surface expression of 78-kDa glucose-regulated protein (GRP78) mediates diabetic nephropathy. Journal of Biological Chemistry. 294:7755-7768. 2019
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IL ‐6 mediatesER expansion during hyperpolarization of alternatively activated macrophages. Immunology and Cell Biology. 97:203-217. 2019 - Microbial regulation of enteric eosinophils and its impact on tissue remodeling and Th2 immunity 2019
- Cadherin-11–mediated adhesion of macrophages to myofibroblasts establishes a profibrotic niche of active TGF-β. Science Signaling. 12:eaao3469. 2019
- Macitentan reduces progression of TGF-β1-induced pulmonary fibrosis and pulmonary hypertension. European Respiratory Journal. 52:1701857-1701857. 2018
- Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis. eLife. 7:e36354. 2018
- Lysyl Oxidase–Like 1 Protein Deficiency Protects Mice from Adenoviral Transforming Growth Factor-β1–induced Pulmonary Fibrosis. American Journal of Respiratory Cell and Molecular Biology. 58:461-470. 2018
- Separate roles of IL-6 and oncostatin M in mouse macrophage polarizationin vitroandin vivo. Immunology and Cell Biology. 96:257-272. 2018
- Synergistic role of HSP90α and HSP90β to promote myofibroblast persistence in lung fibrosis. European Respiratory Journal. 51:1700386-1700386. 2018
- Overexpression of OSM and IL-6 impacts the polarization of pro-fibrotic macrophages and the development of bleomycin-induced lung fibrosis. Scientific Reports. 7:13281. 2017
- Endoplasmic reticulum stress inhibition attenuates hypertensive chronic kidney disease through reduction in proteinuria. Scientific Reports. 7:41572. 2017
- Endoplasmic reticulum stress inhibition limits the progression of chronic kidney disease in the Dahl salt-sensitive rat. American Journal of Physiology: Renal Physiology. 312:F230-F244. 2017
- Fibroblast growth factor-1 attenuates TGF-β1-induced lung fibrosis. Journal of Pathology. 240:197-210. 2016
- Characterization of Proliferating Lesion‐Resident Cells During All Stages of Atherosclerotic Growth. Journal of the American Heart Association. 5:e003945. 2016
- Endoplasmic reticulum stress inhibition reduces hypertension through the preservation of resistance blood vessel structure and function. Journal of Hypertension. 34:1556-1569. 2016
- GRP78 and CHOP modulate macrophage apoptosis and the development of bleomycin-induced pulmonary fibrosis. Journal of Pathology. 239:411-425. 2016
- Stretch-induced Activation of Transforming Growth Factor-β1 in Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. 194:84-96. 2016
- Disruption of Calcium Signaling in Fibroblasts and Attenuation of Bleomycin-Induced Fibrosis by Nifedipine. American Journal of Respiratory Cell and Molecular Biology. 53:450-458. 2015
- Biomarkers in interstitial lung disease: moving towards composite indexes and multimarkers?. Current Pulmonology Reports. 4:125-129. 2015
- Calcium Homeostasis and Ionic Mechanisms in Pulmonary Fibroblasts. American Journal of Respiratory Cell and Molecular Biology. 53:135-148. 2015
- The therapeutic effects of 4-phenylbutyric acid in maintaining proteostasis. The International Journal of Biochemistry and Cell Biology. 61:45-52. 2015
- Development of a Model of Chronic Kidney Disease in the C57BL/6 Mouse with Properties of Progressive Human CKD. BioMed Research International. 2015:1-10. 2015
- Drug development for chronic lung disease - Mission impossible?. Respirology. 20:13-14. 2015
- The endoplasmic reticulum stress inhibitor, 4‐phenylbutyrate, attenuates chronic kidney disease induced by a model of cardiorenal syndrome (1136.12). The FASEB Journal. 28. 2014
- 4-Phenylbutyrate Inhibits Tunicamycin-Induced Acute Kidney Injury via CHOP/GADD153 Repression. PLoS One. 9:e84663-e84663. 2014
- Mechanisms linked to differences in the mutagenic potential of 1,3-dinitropyrene and 1,8-dinitropyrene. Toxicology Reports. 1:459-473. 2014
- Granzyme B Deficiency Exacerbates Lung Inflammation in Mice after Acute Lung Injury. American Journal of Respiratory Cell and Molecular Biology. 49:453-462. 2013
- Protein Misfolding and Endoplasmic Reticulum Stress in Chronic Lung Disease. Chest. 143:1098-1105. 2013
- Adenoviral-Mediated Gene Transfer into Bone Marrow: An Effective Surgical Technique in Rat. European Surgical Research. 50:282-291. 2013
- Local Delivery of GM-CSF Protects Mice from Lethal Pneumococcal Pneumonia. Journal of Immunology. 187:5346-5356. 2011
- In VivoRole of Platelet-Derived Growth Factor–BB in Airway Smooth Muscle Proliferation in Mouse Lung. American Journal of Respiratory Cell and Molecular Biology. 45:566-572. 2011
- Micro-computed tomography of pulmonary fibrosis in mice induced by adenoviral gene transfer of biologically active transforming growth factor-β1. Respiratory Research. 11:181. 2010
- Have advanced research technologies made real impact on respiratory medicine?. Respirology. 15:876-880. 2010
- Essential Role of Osteopontin in Smoking-Related Interstitial Lung Diseases. American Journal of Pathology. 174:1683-1691. 2009
- VEGF ameliorates pulmonary hypertension through inhibition of endothelial apoptosis in experimental lung fibrosis in rats. Journal of Clinical Investigation. 119:1298-1311. 2009
- Circulating Fibrocytes Are an Indicator of Poor Prognosis in Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. 179:588-594. 2009
- VEGF verbessert Pulmonale Hypertonie in einem Lungenfibrosemodell durch verminderte Apoptose mikrovaskulärer Endothelzellen. Pneumologie. 63. 2009
- Role of STAT6 and SMAD2 in a model of chronic allergen exposure: a mouse strain comparison study. Clinical and Experimental Allergy. 39:147-158. 2009
- Comparison between conventional and "clinical" assessment of experimental lung fibrosis. Journal of Translational Medicine. 6:16. 2008
- 1-Nitropyrene (1-NP) induces apoptosis and apparently a non-apoptotic programmed cell death (paraptosis) in Hepa1c1c7 cells. Toxicology and Applied Pharmacology. 230:175-186. 2008
- Targeting fibrosis in respiratory lung disease. Drug Discovery Today: Therapeutic Strategies. 5:97-100. 2008
- The use of small animal imaging in respiratory disease drug discovery. Drug Discovery Today: Therapeutic Strategies. 5:81-85. 2008
- Experimentelle Erzeugung unilateraler Lungenfibrose mittels Bronchoskopie. Pneumologie. 62. 2008
- Kompartment-spezifische Expression von TGF-β abhängigen Genen in einem Emphysem-Tiermodell. Pneumologie. 62. 2008
- Progressive pulmonary fibrosis is mediated by TGF-β isoform 1 but not TGF-β3. The International Journal of Biochemistry and Cell Biology. 40:484-495. 2008
- Pulmonale Hypertonie im AdTGF-β1 Lungenfibrosemodell ist assoziiert mit Verlust an vaskulärer Dichte und PEDF-vermittelter Angiogeneseinhibition. Pneumologie. 62. 2008
- The bleomycin animal model: A useful tool to investigate treatment options for idiopathic pulmonary fibrosis?. The International Journal of Biochemistry and Cell Biology. 40:362-382. 2008
- Three-dimensional computed tomography imaging in an animal model of emphysema. European Respiratory Journal. 30:1082-1089. 2007
- TGF-β, Smad3 and the process of progressive fibrosis. Biochemical Society Transactions. 35:661-664. 2007
- TGFβ and Smad3 link inflammation to progressive fibrosis. International Congress Series. 1302:103-113. 2007
- Bronchoskopie an Ratten: neue Methodik zur Beurteilung von Atemwegserkrankungen im Tiermodell. Pneumologie. 61. 2007
- Die Rolle zirkulierenden mesenchymaler Vorläuferzellen in fibrosierenden Lungenerkrankungen. Pneumologie. 61. 2007
- Transienter Gentransfer von TGFβ1 induziert pulmonalvaskuläres Remodelling und pulmonale Hypertonie. Pneumologie. 61. 2007
- Smad3 Signaling Involved in Pulmonary Fibrosis and Emphysema. Annals of the American Thoracic Society. 3:696-702. 2006
- Gene Therapy for Pulmonary Diseases. Chest. 130:879-884. 2006
- Strategies targeting fibrosis in pulmonary disease. Drug Discovery Today: Therapeutic Strategies. 3:389-394. 2006
- Targeting Genes for Treatment in Idiopathic Pulmonary Fibrosis: Challenges and Opportunities, Promises and Pitfalls. Annals of the American Thoracic Society. 3:389-393. 2006
- The transforming growth factor-beta (TGF-β) family and pulmonary fibrosis. Drug Discovery Today: Disease Mechanisms. 3:99-103. 2006
- Metabolism of nilutamide in rat lung. Biochemical Pharmacology. 71:377-385. 2006
- TGF-β and Smad3 Signaling Link Inflammation to Chronic Fibrogenesis. Journal of Immunology. 175:5390-5395. 2005
- Connective Tissue Growth Factor Is Crucial to Inducing a Profibrotic Environment in “Fibrosis-Resistant” Balb/c Mouse Lungs. American Journal of Respiratory Cell and Molecular Biology. 31:510-516. 2004
- Distribution of nitroreductive activity toward nilutamide in rat. Toxicology and Applied Pharmacology. 201:1-9. 2004
- Reduction of Nilutamide by NO Synthases: Implications for the Adverse Effects of This Nitroaromatic Antiandrogen Drug. Chemical Research in Toxicology. 16:1547-1554. 2003
- Cannabis smoke suppresses antiviral immune responses to influenza A in mice. ERJ Open Research. 00219-2023.
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article
- Pan-lysyl oxidase inhibitor PXS-5505 ameliorates multiple-organ fibrosis by inhibiting collagen crosslinks in rodent models of systemic sclerosis 2021
- Lasting changes to circulating leukocytes in people with mild SARS-CoV-2 infections 2021
- Circulating fibrocytes can identify people with a poor prognosis in idiopathic pulmonary fibrosis 2020
- Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue 2020
- Inhalation: A means to explore and optimize nintedanib’s pharmacokinetic/pharmacodynamic relationship 2020
- FK506-binding protein 13 expression is upregulated in interstitial lung disease and correlated with clinical severity: a potentially protective role 2019
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chapter
- Chapter 29 Growth Factors. 353-361. 2009
- Growth Factors. 353-361. 2009
- Growth factors. 353-361. 2008
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conference paper
- Vascular–Parenchymal Cross-Talk Promotes Lung Fibrosis through BMPR2 Signaling. American Journal of Respiratory and Critical Care Medicine. 1498-1514. 2023
- Cannabis Smoke Exposure Hinders Viral Clearance and Suppresses Immune Responses to Influenza A Infection in Mice. American Journal of Respiratory and Critical Care Medicine. 2023
- Pathogenic Role of Extracellular Heat Shock Protein 90α (HSP90α) in Interstitial Lung Diseases Through Macrophages Programming. American Journal of Respiratory and Critical Care Medicine. 2023
- Reprogramming Rogue Macrophages: Yeast Beta-glucan Microparticles as a Macrophage Modulator for Lung Fibrosis. American Journal of Respiratory and Critical Care Medicine. 2023
- Intrinsic BMP inhibitor Gremlin regulates lung alveolar progenitor cell proliferation and differentiation. American Journal of Respiratory and Critical Care Medicine. 2022
- Involvement of SOX17-Regulated Endothelial Cellular Senescence in IPF and PH Pathogenesis. American Journal of Respiratory and Critical Care Medicine. 2022
- The Importance of Lung Microenvironment on Gremlin1 Regulation and Pulmonary Fibrosis Pathogenesis. American Journal of Respiratory and Critical Care Medicine. 2022
- Alveolar Epithelial Repair Is Regulated via the BMP Signaling Pathway and BMP Inhibitor Gremlin in a Lung Injury Model. American Journal of Respiratory and Critical Care Medicine. 2021
- Effect of Smoking Status on Interstitial Lung Disease: Novel Insights from the Prospective Canadian Registry for Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. 2021
- Margin Status in Lung Tumor Resections: An Observational Study from a Tertiary/Academic Hospital. American Journal of Respiratory and Critical Care Medicine. 2021
- Safety of Surgical Lung Biopsy for Diagnosis of Interstitial Lung Diseases. American Journal of Respiratory and Critical Care Medicine. 2021
- Galectin-3 is elevated following nintedanib treatment. 12.01 - Idiopathic interstitial pneumonias. 6. 2021
- 5P Uncovering the evolution of glioblastoma proteome landscape from primary to the recurrent stage for development of novel diagnostic and predictive biomarkers. Annals of Oncology. S1419-S1419. 2020
- Identification of therapy driven events on proteome landscape of patient matched primary-recurrent Glioblastoma for development of novel diagnostic and predictive biomarkers. Clinical Biochemistry. 83-83. 2020
- Anti-Inflammatory/Anti-Fibrotic Compound PBI-4425 Alleviates Bleomycin- and TGF-ß1-Induced Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. 2020
- Characterizing the Role of ABCF1 in dsDNA Antiviral Responses in Human Airway Epithelial Cells. American Journal of Respiratory and Critical Care Medicine. 2020
- Characterizing the Transcriptomic Signature in Circulating Monocytes and Alternatively Activated Macrophages in Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. 2020
- Integrative -Omics Identify Potential Biomarkers and Therapeutic Targets for Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. 2020
- Intrinsic BMP Inhibitor Gremlin Regulates Lung Alveolar Stem Cell Proliferation and Differentiation. D27. CELLULAR RESPONSES INFORMING LUNG REPAIR. a6389-a6389. 2020
- The Expression and Genetic Mutation of BMPR2 in the Fibrotic Lung Diseases. American Journal of Respiratory and Critical Care Medicine. 2020
- Antifibrotic Effect of PBI-4050 in Human Normal and IPF Lung Fibroblasts, and in AdTGF-b1-Induced Pulmonary Fibrosis Rat Model. American Journal of Respiratory and Critical Care Medicine. 2019
- Assessing the Role of ATF6α in the Alternative Activation of Macrophages in the Progression of Fibrotic Lung Diseases. American Journal of Respiratory and Critical Care Medicine. 2019
- Dectin-1 Is a Marker of Alternatively Activated Macrophages and a Therapeutic Target in Interstitial Fibrotic Lung Diseases. American Journal of Respiratory and Critical Care Medicine. 2019
- Investigating the Expression of CCL18 in Alternatively Activated Macrophages and in the Progression of Different Fibrotic Lung Diseases. American Journal of Respiratory and Critical Care Medicine. 2019
- Mechanical stress-induced mast cell degranulation activates TGF-β1 signalling pathway in pulmonary fibrosis. Thorax. 455-465. 2019
- The IRE/XBP1 Pathway Is Activated in Alternatively Activated Macrophages in Interstitial Fibrotic Lung Disease. American Journal of Respiratory and Critical Care Medicine. 2019
- The Vascular-Parenchymal Crosstalk Regulates Lung Fibrosis Through Bmpr2 and Ctgf Signaling. C28. PATHWAYS OF LUNG MORPHOGENESIS. a4433-a4433. 2019
- The vascular-parenchymal crosstalk regulates lung fibrosis through BMPR2 and CTGF signaling. Idiopathic Interstitial Penumonias. pp210. 2019
- A NEW MECHANISM OF LATENT TGF-B1 PRESENTATION IN LUNG. Wound Repair and Regeneration. A14-A14. 2018
- A New Mechanism of Latent Tgf-b1 Presentation in Lung. Wound Repair and Regeneration. A34-A34. 2018
- Evaluation of novel LOXL2-selective inhibitors in models of pulmonary fibrosis. European Respiratory Journal. 2017
- Nintedanib prevents IL-6-mediated secretion of CCL-18 in alternatively activated macrophages and transition of fibroblasts to myofibroblasts. Mechanisms of Lung Injury and Repair. pa3478. 2017
- Identification And Validation Of Unique And Shared M2 Macrophage Biomarkers Between Murine Models And Human Disease Using Bioinformatic Gene Expression Analysis. American Journal of Respiratory and Critical Care Medicine. 2017
- Loxl1 Null Mice Are Protected From Tgf-beta 1 Induced Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. 2017
- Nintedanib Attenuates The Polarization Of Profibrotic Macrophages Through The Inhibition Of Tyrosine Phosphorylation On Csf1 Receptor. American Journal of Respiratory and Critical Care Medicine. 2017
- Silica-Induced Pulmonary Fibrosis Occurs With The Activation Of Macrophage Polarization Through Marco And In A Tgf-beta 1-Independent Manner. American Journal of Respiratory and Critical Care Medicine. 2017
- The Hsp90 Inhibitor Radicicol As A Bioinformatically-Derived Drug For M2 Macrophage Phenotype Inhibition. American Journal of Respiratory and Critical Care Medicine. 2017
- Characterizing The Maturation Of Tgf-beta Induced Pulmonary Fibrotic Scar: Quantitation Of Extracellular Matrix Protein Synthesis, Remodeling And Crosslinking Rates. American Journal of Respiratory and Critical Care Medicine. 2016
- How Basic Science Methodology Has Changed In The Context Of The Bleomycin Model Of Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. 2016
- Il-6 Mediated Hyperpolarization Of Profibrotic Macrophages Is Dependent On Spliced Xbp1. American Journal of Respiratory and Critical Care Medicine. 2016
- Macitentan Prevents Pulmonary Fibrosis Progression And Secondary Pulmonary Hypertension Induced By Tgf-beta 1 Overexpression In Rats. American Journal of Respiratory and Critical Care Medicine. 2016
- Requirement Of Il-6 For Maximal M2 Macrophage Accumulation, And Growth Of Ectopically Delivered B16 Melanoma, In Mouse Lungs Upon Oncostatin M Overexpression. American Journal of Respiratory and Critical Care Medicine. 2016
- Effect Of Allergen Challenge On Inflammation Induced By Toll-Like Receptor Stimulation In A Nasal Challenge Model. American Journal of Respiratory and Critical Care Medicine. 2015
- Ire1 Mediated Xbp1 Splicing Is Critical For Pulmonary Fibroblast Proliferation And Differentiation. American Journal of Respiratory and Critical Care Medicine. 2015
- Differential effects of ambient diesel carcinogens on inflammation and DNA damage response in cells relevant for lung toxicity. Toxicology Letters. S25-S25. 2014
- Fkbp13 Deficiency Leads To Increased Pulmonary Er Stress, Inflammation And Fibrosis After Bleomycin Administration. American Journal of Respiratory and Critical Care Medicine. 2014
- Grp78 Heterozygosity Abrogates Bleomycin-Induced Lung Fibrosis By Modulating Er-Resident Protein Folding Capacity. American Journal of Respiratory and Critical Care Medicine. 2014
- Inhaled Pirfenidone Improves Animal Efficacy Through Superior Pulmonary And Vascular Pharmacokinetics. American Journal of Respiratory and Critical Care Medicine. 2014
- Nifedipine Attenuates Bleomycin-Induced Fibrosis By Blocking Calcium Wave Activity. American Journal of Respiratory and Critical Care Medicine. 2014
- Interdependence of HIF1 alpha/TGF beta 1 activity in induction of pulmonary fibrosis. European Respiratory Journal. 2013
- 4-Phenylbutyrate Prevents Upr Activation And Myofibroblast Differentiation In Experimental Bleomycin-Induced Lung Fibrosis. American Journal of Respiratory and Critical Care Medicine. 2013
- Fkbp13 Deficiency Leads To An Exacerbated Inflammatory Response And Increased Lung Compliance Following Cigarette Smoke Exposure. American Journal of Respiratory and Critical Care Medicine. 2013
- Grp78 Heterozygosity Protects Against Bleomycin-Induced Lung Fibrosis And Inflammation. American Journal of Respiratory and Critical Care Medicine. 2013
- O001 Regulation of tissue remodelling by Oncostatin M in mouse lung is IL-6- and SMAD3-independent. Cytokine. 497-497. 2012
- Assessment Of Housekeeping Genes In Inflammatory Mouse Models Of Lung Disease. C31. REGULATION OF LUNG INFLAMMATION. a4163-a4163. 2012
- Adenoviral Gene Transfer Of Granulocyte/Macrophage Colony Stimulating Factor Enhances Pulmonary Host Defense And Survival From Pneumococcal Pneumonia In Mice. American Journal of Respiratory and Critical Care Medicine. 2011
- Effects of Bacterial Infection withPseudomonas aeruginosaon Experimental Pulmonary Fibrosis.. American Journal of Respiratory and Critical Care Medicine. 2009
- TGF-beta Antagonist Antibody 1D11 Blocks Experimental Progressive Pulmonary Fibrosis.. American Journal of Respiratory and Critical Care Medicine. 2009
- VEGF Overexpression during Fibrogenesis Reduces Endothelial Cell Apoptosis and Improves Pulmonary Hypertension.. American Journal of Respiratory and Critical Care Medicine. 2009
- Metabolism of nitro-polycyclic aromatic hydrocarbons elicits apoptotic and necrotic responses in Hepa1c1c7 cells. Toxicology and Applied Pharmacology. 308-308. 2004
- Metabolism of the nitroaromatic nilutamide by freshly isolated lung cells and by recombinant NO synthase. Drug Metabolism Reviews. 112-112. 2003
- Drug-induced infiltrative lung disease.. European Respiratory Journal. 93s-100s. 2001