selected scholarly activity
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academic article
- Dupilumab, severe asthma airway responses, and SARS‐CoV‐2 serology. Allergy: European Journal of Allergy and Clinical Immunology. 76:957-958. 2021
- IL‐13 signature in severe adult asthmatics with airway neutrophilia: a new endotype to treat!. Allergy: European Journal of Allergy and Clinical Immunology. 2021
- Asthma exacerbations on benralizumab are largely non‐eosinophilic. Allergy: European Journal of Allergy and Clinical Immunology. 76:375-379. 2021
- Functionally Active Eosinophil Purification from Peripheral Blood. Methods in Molecular Biology. 2241:15-25. 2021
- Monitoring eosinophils to guide therapy with Biologics in Asthma: does the compartment matter?. Allergy: European Journal of Allergy and Clinical Immunology. 2020
- The Role of the TL1A/DR3 Axis in the Activation of Group 2 Innate Lymphoid Cells in Subjects with Eosinophilic Asthma. American Journal of Respiratory and Critical Care Medicine. 202:1105-1114. 2020
- Exacerbations of Severe Asthma While on Anti–IL-5 Biologics. Journal of Investigational Allergology and Clinical Immunology. 30:307-316. 2020
- Suboptimal treatment response to anti-IL-5 monoclonal antibodies in severe eosinophilic asthmatics with airway autoimmune phenomena. European Respiratory Journal European Respiratory Journal, Supplement. 56:2000117-2000117. 2020
- Non-Malignant Respiratory Illnesses in Association with Occupational Exposure to Asbestos and Other Insulating Materials: Findings from the Alberta Insulator Cohort. International Journal of Environmental Research and Public Health. 17:7085-7085. 2020
- Sputum and serum immunoglobulins in adult asthmatics with recurrent respiratory tract infections. Allergy: European Journal of Allergy and Clinical Immunology. 75:2105-2108. 2020
- Luminal Eosinophil Cell Death as a Biomarker for Loss of Asthma Control?. Chest. 157:1680-1681. 2020
- New paradigm in asthma management: Switching between biologics!. Allergy: European Journal of Allergy and Clinical Immunology. 75:743-745. 2020
- Omalizumab in patients with severe asthma and persistent sputum eosinophilia. Canadian Journal of Allergy and Clinical Immunology Allergy, Asthma and Clinical Immunology. 15:21. 2019
- CT and Functional MRI to Evaluate Airway Mucus in Severe Asthma. Chest. 155:1178-1189. 2019
- Rapid quantification of sputum eosinophil peroxidase on a lateral flow test strip. Allergy: European Journal of Allergy and Clinical Immunology. 74:1176-1178. 2019
- Eosinophil-derived IL-13 promotes emphysema. European Respiratory Journal European Respiratory Journal, Supplement. 53:1801291-1801291. 2019
- Sputum Antineutrophil Cytoplasmic Antibodies in Serum Antineutrophil Cytoplasmic Antibody–Negative Eosinophilic Granulomatosis with Polyangiitis. American Journal of Respiratory and Critical Care Medicine. 199:158-170. 2019
- Modulation of human airway smooth muscle biology by human adipocytes. Respiratory Research. 19:33. 2018
- Airway Eosinophilopoietic and Autoimmune Mechanisms of Eosinophilia in Severe Asthma. Immunology and Allergy Clinics of North America Clinics in Immunology and Allergy. 38:639-654. 2018
- Benralizumab attenuates airway eosinophilia in prednisone-dependent asthma. Journal of Allergy and Clinical Immunology. 141:1529-1532.e8. 2018
- Sputum autoantibodies in patients with severe eosinophilic asthma. Journal of Allergy and Clinical Immunology. 141:1269-1279. 2018
- Endogenous peroxidases in sputum interfere with horse-radish peroxidase-based ELISAs. Journal of Immunological Methods. 454:76-79. 2018
- Autoimmune Responses in Severe Asthma. Allergy, Asthma and Immunology Research. 10:428-428. 2018
- Eosinophil Extracellular Traps and Inflammatory Pathologies—Untangling the Web!. Frontiers in Immunology. 9:2763. 2018
- Human Bronchial Epithelial Cell–derived Factors from Severe Asthmatic Subjects Stimulate Eosinophil Differentiation. American Journal of Respiratory Cell and Molecular Biology. 58:99-106. 2018
- Weight-adjusted Intravenous Reslizumab in Severe Asthma with Inadequate Response to Fixed-Dose Subcutaneous Mepolizumab. American Journal of Respiratory and Critical Care Medicine. 197:38-46. 2018
- Airway autoimmune responses in severe eosinophilic asthma following low-dose Mepolizumab therapy. Canadian Journal of Allergy and Clinical Immunology Allergy, Asthma and Clinical Immunology. 13:2. 2017
- Improved recovery of functionally active eosinophils and neutrophils using novel immunomagnetic technology. Journal of Immunological Methods. 449:44-55. 2017
- Enhanced expression of Organic Cation Transporters in bronchial epithelial cell layers following insults associated with asthma – Impact on salbutamol transport. European Journal of Pharmaceutical Sciences. 106:62-70. 2017
- Glucocortiosteroid subsensitivity and asthma severity. Current Opinion in Pulmonary Medicine. 23:78-88. 2017
- Blood or sputum eosinophils to guide asthma therapy?. The Lancet Respiratory Medicine. 3:824-825. 2015
- Thymic stromal lymphopoietin and IL-33 modulate migration of hematopoietic progenitor cells in patients with allergic asthma. Journal of Allergy and Clinical Immunology. 135:1594-1602. 2015
- Anti-IL5 therapy for asthma and beyond. World Allergy Organization Journal. 7:32-32. 2014
- In-cell Western™ detection of organic cation transporters in bronchial epithelial cell layers cultured at an air–liquid interface on Transwell ® inserts. Journal of Pharmacological and Toxicological Methods. 68:184-189. 2013
- Evaluation of air-interfaced Calu-3 cell layers for investigation of inhaled drug interactions with organic cation transporters in vitro. International Journal of Pharmaceutics. 426:7-14. 2012
- IL-13 signature in severe adult asthmatics with airway neutrophilia: a new endotype to treat!
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conference paper
- Suboptimal response to benralizumab is not associated with inadequate eosinophil suppression. Allergy: European Journal of Allergy and Clinical Immunology. 405-406. 2020
- TL1A/DR3 Axis Promotes Group 2 Innate Lymphocyte Activation in Eosinophilic Asthmatics. American Journal of Respiratory and Critical Care Medicine. 2020
- The Role of Excess Airway Macrophage Iron on Infective Exacerbations of Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. 2020
- A single-center observational study assessing response to mepolizumab in severe eosinophilic asthma. European Respiratory Journal European Respiratory Journal, Supplement. 2019
- Omalizumab in Patients with Severe Asthma and Persistent Sputum Eosinophilia. Journal of Allergy and Clinical Immunology. AB434-AB434. 2019
- Sputum and serum immunoglobulins in patients with asthma and recurrent neutrophilic bronchitis. Journal of Allergy and Clinical Immunology. AB227-AB227. 2019
- Sputum autoantibody-mediated macrophage dysfunction in severe eosinophilic asthmatics with recurrent infections. Journal of Allergy and Clinical Immunology. AB189-AB189. 2019
- Airway Luminal Contributors to Magnetic Resonance Imaging Ventilation Heterogeneity in Severe Asthma. American Journal of Respiratory and Critical Care Medicine. 2019
- Autoantigen Array Reveals Decreased Expression of Autoantibodies in Sputum of Patients with Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. 2019
- High Failure Rate of Anti-IL-5 Therapies in Prednisone-Dependent Asthma Is Associated with Airway Autoimmune Responses. American Journal of Respiratory and Critical Care Medicine. 2019
- Increased B-Cells in the Airways of Patients with Severe Eosinophilic Asthma: A Local Auto-Inflammatory Process. American Journal of Respiratory and Critical Care Medicine. 2019
- Increased sputum B cells in severe eosinophilic asthma: a local auto-inflammatory process. European Respiratory Journal European Respiratory Journal, Supplement. 2018
- Benralizumab attenuates airway eosinophilopoietic processes in prednisone-dependent asthma. European Respiratory Journal European Respiratory Journal, Supplement. 2017
- Weight-adjusted Intravenous Reslizumab Attenuates Airway Eosinophilia in Severe Asthmatics compared to 100 mg Subcutaneous Mepolizumab. European Respiratory Journal European Respiratory Journal, Supplement. 2017
- Sputum anti-neutrophil cytoplasmic antibodies in eosinophilic granulomatosis and polyangiitis patients with respiratory involvement. Allergy: European Journal of Allergy and Clinical Immunology. 756-756. 2017
- SPUTUM ANTI-NEUTROPHIL CYTOPLASMIC ANTIBODIES (ANCA) IN EOSINOPHILIC GRANULAMATOSIS AND POLYANGIITIS (EGPA). Rheumatology. 17-17. 2017
- Pathogenic sputum autoantibodies in eosinophilic severe asthma: a novel autoimmune endotype. Allergy: European Journal of Allergy and Clinical Immunology. 30-30. 2016
- Pathogenic Autoantibodies in Patients with Severe Asthma and Sputum Eosinophils. Journal of Allergy and Clinical Immunology. AB409-AB409. 2016
- Eosinophil Peroxidase As an Autoimmune Target in Eosinophilic Airway Disorders. Journal of Allergy and Clinical Immunology. AB221-AB221. 2015
- Human Bronchial Epithelial Cell-Derived Factors from Severe Asthmatics Can Stimulate Local Eosinophilopoetic Responses. Journal of Allergy and Clinical Immunology. AB148-AB148. 2015