Journal article
Impact of former smoking exposure on airway eosinophilic activation and autoimmunity in patients with severe asthma
Abstract
INTRODUCTION: Severe eosinophilic asthma is characterised by frequent exacerbations and a relative insensitivity to steroids. Experimentally, smoking may induce eosinophilic airway inflammation, but the impact in patients with severe asthma is not clear.
OBJECTIVE: To investigate the association between smoking exposure in patients with severe asthma, and eosinophilic inflammation and activation, as well as airway autoimmunity and steroid …
Authors
Klein DK; Silberbrandt A; Frøssing L; Hvidtfeldt M; von Bülow A; Nair P; Mukherjee M; Porsbjerg C
Journal
European Respiratory Journal, Vol. 60, No. 4,
Publisher
European Respiratory Society (ERS)
Publication Date
October 2022
DOI
10.1183/13993003.02446-2021
ISSN
0903-1936