Tumor Microenvironment Concept

subject area of

• A Toolkit for Single-Nucleus Characterization of Glioblastoma.  Journal Articles
• A rational relationship: Oncolytic virus vaccines as functional partners for adoptive T cell therapy  Journal Articles
• Analysis of ductal carcinoma in situ by self-reported race reveals molecular differences related to outcome.  Journal Articles
• Application of 3D, 4D, 5D, and 6D bioprinting in cancer research: what does the future look like?  Journal Articles
• Association BetweenNRASandBRAFMutational Status and Melanoma-Specific Survival Among Patients With Higher-Risk Primary Melanoma  Journal Articles
• Breast cancer, alcohol, and phosphate toxicity  Journal Articles
• CD70 as an actionable immunotherapeutic target in recurrent glioblastoma and its microenvironment  Journal Articles
• CXCR6 by increasing retention of memory CD8⁺ T cells in the ovarian tumor microenvironment promotes immunosurveillance and control of ovarian cancer  Journal Articles
• Cancer Organoids as reliable disease models to drive clinical development of novel therapies.  Journal Articles
• Characterizing Endocrine Status, Tumor Hypoxia and Immunogenicity for Therapy Success in Epithelial Ovarian Cancer  Journal Articles
• Charting a killer course to the solid tumor: strategies to recruit and activate NK cells in the tumor microenvironment  Journal Articles
• Combined Radionuclide Therapy and Immunotherapy for Treatment of Triple Negative Breast Cancer  Journal Articles
• Comparative analysis of syngeneic mouse models of high-grade serous ovarian cancer  Journal Articles
• Composite analysis of immunological and metabolic markers defines novel subtypes of triple negative breast cancer  Journal Articles
• Concurrent Use of Statins in Patients Undergoing Curative Intent Treatment for Triple Negative Breast Cancer: A Systematic Review and Meta-Analysis  Journal Articles
• Constitutive expression of interleukin-27 diminishes proinflammatory cytokine production without impairing effector function of engineered T cells  Journal Articles
• Cytokines in oncolytic virotherapy  Journal Articles
• De novo necroptosis creates an inflammatory environment mediating tumor susceptibility to immune checkpoint inhibitors  Journal Articles
• Deciphering pericyte-induced temozolomide resistance in glioblastoma with a 3D microphysiological system mimicking the biomechanical properties of brain tissue.  Journal Articles
• Deciphering the Immunomodulatory Capacity of Oncolytic Vaccinia Virus to Enhance the Immune Response to Breast Cancer  Journal Articles
• Detection of Tumor Antigen-Specific T-Cell Responses After Oncolytic Vaccination  Journal Articles
• Determinants for Antitumor and Protumor Effects of Programmed Cell Death  Journal Articles
• Disulfide-Cross-Linked Nanogel-Based Nanoassemblies for Chemotherapeutic Drug Delivery  Journal Articles
• Enzyme-responsive mannose-grafted magnetic nanoparticles for breast and liver cancer therapy and tumor-associated macrophage immunomodulation  Journal Articles
• Epigenetic therapy inhibits metastases by disrupting premetastatic niches  Journal Articles
• Expanded human NK cells from lung cancer patients sensitize patients’ PDL1−negative tumors to PD1-blockade therapy  Journal Articles
• Expression of hypoxia inducible factor–dependent neuropeptide Y receptors Y1 and Y5 sensitizes hypoxic cells to NPY stimulation  Journal Articles
• Functional Analysis of Tumor-Infiltrating Myeloid Cells by Flow Cytometry and Adoptive Transfer  Journal Articles
• GBM secretome induces transient transformation of human neural precursor cells  Journal Articles
• Gelatin methacryloyl and Laponite bioink for 3D bioprinted organotypic tumor modeling  Journal Articles
• Glucose‐regulated protein (GRP78) is an important cell surface receptor for viral invasion, cancers, and neurological disorders  Journal Articles
• HDACi promotes inflammatory remodeling of the tumor microenvironment to enhance epitope spreading and antitumor immunity  Journal Articles
• How I Do It: Maintenance avelumab for advanced urothelial carcinoma.  Journal Articles
• Humanized zebrafish enhance human hematopoietic stem cell survival and promote acute myeloid leukemia clonal diversity  Journal Articles
• Humanized zebrafish enhance human hematopoietic stem cell survival and promote acute myeloid leukemia clonal diversity.  Journal Articles
• Hypoxia-Driven Immune Escape in the Tumor Microenvironment  Journal Articles
• Immune-Infiltrated Cancer Spheroid Model with Vascular Recirculation Reveals Temporally Dependent and Tissue-Specific Macrophage Recruitment.  Journal Articles
• Impact of Interventional Oncology Therapies on Tumor Microenvironment and Strategies to Enhance Their Efficacy  Journal Articles
• In-vitro assays for immuno-oncology drug efficacy assessment and screening for personalized cancer therapy: scopes and challenges.  Journal Articles
• Injectable hydrogels for personalized cancer immunotherapies  Journal Articles
• Interactions Between the Immune System and Cancer: A Brief Review of Non-spatial Mathematical Models  Journal Articles
• Intraductal Adaptation of the 4T1 Mouse Model of Breast Cancer Reveals Effects of the Epithelial Microenvironment on Tumor Progression and Metastasis  Journal Articles
• Intrinsic suppression of type I interferon production underlies the therapeutic efficacy of IL-15-producing natural killer cells in B-cell acute lymphoblastic leukemia  Journal Articles
• Mathematical modeling of the synergetic effect between radiotherapy and immunotherapy.  Journal Articles
• Mechanism and non-mechanism based imaging biomarkers for assessing biological response to treatment in non-small cell lung cancer  Journal Articles
• Metabolic adaptations determine whether natural killer cells fail or thrive within the tumor microenvironment  Journal Articles
• Metabolic flexibility determines human NK cell functional fate in the tumor microenvironment  Journal Articles
• Molecular Hallmarks of Multiparametric Magnetic Resonance Imaging Visibility in Prostate Cancer  Journal Articles
• Neoadjuvant programmed cell death 1 blockade combined with chemotherapy for resectable esophageal squamous cell carcinoma  Journal Articles
• Next Wave of Targets in the Treatment of Advanced Renal Cell Carcinoma  Journal Articles
• Niche displacement of human leukemic stem cells uniquely allows their competitive replacement with healthy HSPCs  Journal Articles
• Oncolytic Maraba virus armed with tumor antigen boosts vaccine priming and reveals diverse therapeutic response patterns when combined with checkpoint blockade in ovarian cancer  Journal Articles
• Oncolytic Viruses: Therapeutics With an Identity Crisis  Journal Articles
• Ovarian tumour growth is characterized by mevalonate pathway gene signature in an orthotopic, syngeneic model of epithelial ovarian cancer  Journal Articles
• Overcoming Resistance Mechanisms to Immune Checkpoint Inhibitors: Leveraging the Anti-Tumor Immune Response  Journal Articles
• Pan-urologic cancer genomic subtypes that transcend tissue of origin  Journal Articles
• Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliary tract cancer (KEYNOTE-966): a randomised, double-blind, placebo-controlled, phase 3 trial  Journal Articles
• Pituitary metastasis: From pathology to clinical and radiological considerations  Journal Articles
• Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity  Journal Articles
• SAPPHIRE: phase III study of sitravatinib plus nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer  Journal Articles
• Synergistic anti-tumor efficacy of oncolytic influenza viruses and B7-H3 immune- checkpoint inhibitors against IC-resistant lung cancers  Journal Articles
• TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment  Journal Articles
• Targeting Hypoxia-Inducible Factor 1α in a New Orthotopic Model of Glioblastoma Recapitulating the Hypoxic Tumor Microenvironment.  Journal Articles
• Targeting tumor-stroma communication by blocking endothelin-1 receptors sensitizes high-grade serous ovarian cancer to PARP inhibition  Journal Articles
• The Complex Tumor Microenvironment in Ovarian Cancer: Therapeutic Challenges and Opportunities  Journal Articles
• The Influence of Macrophages and the Tumor Microenvironment on Natural Killer Cells  Journal Articles
• The breast tumor microenvironment alters the phenotype and function of natural killer cells  Journal Articles
• The cross-talk between the macro and micro-environment in precursor lesions of pancreatic cancer leads to new and promising circulating biomarkers  Journal Articles
• The endothelin-1-driven tumor-stroma feed-forward loops in high-grade serous ovarian cancer  Journal Articles
• The impact of the ovarian microenvironment on the anti-tumor effect of SPARC on ovarian cancer¹This article is part of Special Issue entitled Asilomar Chromatin and has undergone the Journal’s usual peer review process.  Journal Articles
• The p38-MK2-HuR pathway potentiates EGFRvIII–IL-1β-driven IL-6 secretion in glioblastoma cells  Journal Articles
• The senescent microenvironment promotes the emergence of heterogeneous cancer stem-like cells  Journal Articles
• The tumor microenvironment’s in pancreatic cancer: Effects on immunotherapy success and novel strategies to overcome the hostile environment  Journal Articles
• Thinking small to win big? A critical review on the potential application of extracellular vesicles for biomarker discovery and new therapeutic approaches in pancreatic cancer  Journal Articles
• Thrombospondins in the tumor microenvironment  Journal Articles
• Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers  Journal Articles