Receptors, Thrombin Concept

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• A trypsin-like platelet protease propagates protease-activated receptor-1 cleavage and platelet activation  Journal Articles
• Atorvastatin Delays Murine Platelet Activation In Vivo Even in the Absence of Endothelial NO Synthase  Journal Articles
• Binding of Thrombin to the G-protein-linked Receptor, and Not to Glycoprotein Ib, Precedes Thrombin-mediated Platelet Activation  Journal Articles
• Conditions influencing release of granule contents from human platelets in citrated plasma induced by ADP or the thrombin receptor activating peptide SFLLRN: Direct measurement of percent release of β-thromboglobulin and assessment by flow cytometry of P-selectin expression \textbar Request PDF  Other
• Contrasting Effects of Thrombin and the Thrombin Receptor Peptide, SFLLRN, on Aggregation and Release of 14C-Serotonin by Human Platelets Pretreated with Chymotrypsin or Serratia marcescens Protease  Other
• Coordinate Activation of Human Platelet Protease-activated Receptor-1 and -4 in Response to Subnanomolar α-Thrombin  Journal Articles
• Differences between platelet phosphoinositide metabolism stimulated by thrombin or SFLLRN are not accounted for by interaction of thrombin with glycoprotein Ib  Journal Articles
• Early Intraplatelet Signaling Enhances the Release of Human Platelet PAR-1 and -4 Amino-Terminal Peptides in Response to Thrombin  Journal Articles
• Effects of Thrombin and the Thrombin Receptor Activating Peptide, SFLLRN, on Redistribution of Platelet α-Granule Contents Are Similar and Independent of the Extent of Thromboxane Formation  Journal Articles
• Enhanced TRAP-induced platelet aggregation with dabigatran — Clinical perspective  Journal Articles
• G-Protein–Coupled Receptors as Signaling Targets for Antiplatelet Therapy  Journal Articles
• HUMAN PLATELET THROMBIN RECEPTORS  Journal Articles
• Pretreatment of Human Platelets with Plasmin Inhibits Responses toThrombin, but Potentiates Responses to Low Concentrations of Aggregating Agents, Including the Thrombin Receptor Activating Peptide, SFLLRN  Journal Articles
• Protease activated receptors 1 and 4 govern the responses of human platelets to thrombin  Journal Articles
• The Cleaved Peptide of PAR1 Results in a Redistribution of the Platelet Surface GPIb-IX-V Complex to the Surface-Connected Canalicular System  Journal Articles
• The mechanism of action of thrombin inhibitors.  Journal Articles
• Thrombin Generation and Presence of Thrombin Receptor in Ovarian Follicles1  Journal Articles
• Thrombin binding to platelets and their activation in plasma  Journal Articles
• Vorapaxar, Combination Antiplatelet Therapy, and Stroke∗  Journal Articles