Clinical Trials, Phase II as Topic
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A Canadian phase II study evaluating the efficacy of rituximab in the management of patients with relapsed/refractory thrombotic thrombocytopenic purpura Conference Paper
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A Phase I Study of OGX-011, a 2′-Methoxyethyl Phosphorothioate Antisense to Clusterin, in Combination with Docetaxel in Patients with Advanced Cancer Academic Article
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A Replacement for Warfarin Academic Article
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A comparison of a new multinomial stopping rule with stopping rules of fleming and gehan in single arm phase II cancer clinical trials Academic Article
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A multidisciplinary “think tank”: the top 10 clinical trial opportunities in transfusion medicine from the National Heart, Lung, and Blood Institute-sponsored 2009 state-of-the-science symposium Academic Article
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A semimechanistic-physiologic population pharmacokinetic/pharmacodynamic model for neutropenia following pemetrexed therapy Academic Article
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Adjuvant oncolytic virotherapy for personalized anti-cancer vaccination Academic Article
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Advances in Antithrombotic Therapy: Novel Agents Academic Article
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Andexanet alfa for the treatment of hemorrhage Academic Article
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Antithrombotic therapy for stroke prevention in atrial fibrillation and mechanical heart valves Academic Article
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Apixaban in Acute Coronary Syndromes Academic Article
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CCI-779 Wyeth. Academic Article
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Cardiovascular Outcomes Trials in Type 2 Diabetes: Where Do We Go From Here? Reflections From aDiabetes CareEditors’ Expert Forum Academic Article
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Challenges in the conduct and interpretation of phase II (pilot) randomized trials Academic Article
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Clinical application of a semimechanistic-physiologic population PK/PD model for neutropenia following pemetrexed therapy Academic Article
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Clinical cooperative trials of the National Cancer Institute of Canada Clinical Trials Group Breast Cancer Site Group. Academic Article
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Clinical trial opportunities in hemostasis and thrombosis: NHBLI State-of-the-science symposium Academic Article
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Colchicine pre-treatment and post-treatment does not worsen bleeding or functional outcome after collagenase-induced intracerebral hemorrhage Academic Article
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Combination 13-cis-retinoic acid and interferon alpha-2a in the therapy of solid tumors. Academic Article
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Comparison of Outcomes of Phase II Studies and Subsequent Randomized Control Studies Using Identical Chemotherapeutic Regimens Conference Paper
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Complete Response as an Intermediate End Point in Patients Receiving Salvage Systemic Therapy for Urothelial Carcinoma Academic Article
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Correlation of single arm versus randomised phase 2 oncology trial characteristics with phase 3 outcome Academic Article
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Current Incidence and Outcomes of Gastrointestinal Mesenchymal Tumors Including Gastrointestinal Stromal Tumors Academic Article
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DNA methyltransferase inhibitors—state of the art Academic Article
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Dabigatran Etexilate: Future Directions in Anticoagulant Treatment Academic Article
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Development of adapted RECIST criteria to assess response in lymphoma and their comparison to the International Workshop Criteria Academic Article
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Direct-acting antiviral therapies for hepatitis C genotype 1 infection: a multiple treatment comparison meta-analysis Academic Article
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Drug evaluation: E-5564. Academic Article
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Efficacy and safety of rolapitant for prevention of chemotherapy-induced nausea and vomiting over multiple cycles of moderately or highly emetogenic chemotherapy Academic Article
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Evaluation of Adverse Events Experienced by Older Patients Participating in Studies of Molecularly Targeted Agents Alone or in Combination Academic Article
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Five-Factor Prognostic Model for Survival of Post-Platinum Patients with Metastatic Urothelial Carcinoma Receiving PD-L1 Inhibitors Academic Article
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Fondaparinux, the first selective factor Xa inhibitor Academic Article
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Heterogeneity among lists of cautioned or prohibited drugs in protocols of early-phase oncology trials Academic Article
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Human Gene Marker/Therapy Clincal Protocols (Complete Updated Listings) Academic Article
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Impact of Response to Prior Chemotherapy in Patients With Advanced Urothelial Carcinoma Receiving Second-Line Therapy: Implications for Trial Design Academic Article
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Impact of the Number of Prior Lines of Therapy and Prior Perioperative Chemotherapy in Patients Receiving Salvage Therapy for Advanced Urothelial Carcinoma: Implications for Trial Design Academic Article
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Implementation of Timeline Reforms Speeds Initiation of National Cancer Institute-Sponsored Trials Academic Article
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Improved 5-Factor Prognostic Classification of Patients Receiving Salvage Systemic Therapy for Advanced Urothelial Carcinoma Academic Article
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Incidence of delayed venous thromboembolic events in patients undergoing abdominal and pelvic surgery for cancer: a systematic review and meta‐analysis Academic Article
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Incomplete Cross-Resistance Between Taxanes for Advanced Urothelial Carcinoma: Implications for Clinical Practice and Trial Design Academic Article
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Integrated safety and efficacy analysis of once-daily fluticasone furoate for the treatment of asthma Academic Article
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Investigating the appropriateness of different concordance measures in a time‐to‐event setting Academic Article
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Investigating the potential clinical benefit of Selumetinib in resensitising advanced iodine refractory differentiated thyroid cancer to radioiodine therapy (SEL-I-METRY): protocol for a multicentre UK single arm phase II trial Academic Article
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Magnitude of benefit of the addition of bevacizumab to first-line chemotherapy for metastatic colorectal cancer: meta-analysis of randomized clinical trials Conference Paper
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Management of Patients with Acute Coronary Syndromes Academic Article
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National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: VI. Design of Clinical Trials Working Group Report Academic Article
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New Anticoagulant Drugs Academic Article
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New Anticoagulants for Treatment of Venous Thromboembolism Academic Article
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New Antithrombotic Drugs Academic Article
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Nomograms to Predict Serious Adverse Events in Phase II Clinical Trials of Molecularly Targeted Agents Academic Article
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Objective Responses in Patients with Malignant Melanoma or Renal Cell Cancer in Early Clinical Studies Do Not Predict Regulatory Approval Academic Article
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Optimizing vaccine-induced CD8+T-cell immunity: focus on recombinant adenovirus vectors Academic Article
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Otamixaban in acute coronary syndromes Academic Article
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Our Choice: study protocol for a randomized controlled trial for optimal implementation of psoriasis treatment by the integration of Chinese and western medicine Academic Article
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Overstated Conclusions of a Pooled Analysis of Bevacizumab in Colon Cancer Academic Article
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Overview of the New Oral Anticoagulants Academic Article
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Panorama From the Oncolytic Virotherapy Summit Academic Article
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Patient Eligibility and Trial Design for the Salvage Therapy of Advanced Urothelial Carcinoma Academic Article
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Pentasaccharide Org31540/SR90107A clinical trials update: Lessons for practice Academic Article
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Phase I/II trials of 186Re-HEDP in metastatic castration-resistant prostate cancer: post-hoc analysis of the impact of administered activity and dosimetry on survival Academic Article
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Phase II Stopping Rules That Employ Response Rates and Early Progression Academic Article
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Phosphoinositide 3-kinase inhibitors in advanced breast cancer: A systematic review and meta-analysis Academic Article
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Posttreatment prognostic nomogram for patients with metastatic urothelial cancer completing first-line cisplatin-based chemotherapy Academic Article
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Preclinical pharmacokinetics, biodistribution, radiation dosimetry and acute toxicity studies required for regulatory approval of a Clinical Trial Application for a Phase I/II clinical trial of 111In-BzDTPA-pertuzumab Academic Article
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Profile of betrixaban and its potential in the prevention and treatment of venous thromboembolism Academic Article
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Proton Pump Inhibitors and Survival Outcomes in Patients With Metastatic Renal Cell Carcinoma Academic Article
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Proton pump inhibitors: the beginning of the end or the end of the beginning? Academic Article
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Quantitative evaluation of single-arm versus randomized phase II cancer clinical trials Academic Article
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Randomized Phase II Trials: Inevitable or Inadvisable? Academic Article
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Randomized, controlled clinical trials in sepsis: Has methodological quality improved over time? Academic Article
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Remote ischemic conditioning in necrotizing enterocolitis: study protocol of a multi-center phase II feasibility randomized controlled trial Academic Article
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Response of Primary Renal Cell Carcinoma to Systemic Therapy Academic Article
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Rolapitant for the treatment of chemotherapy-induced nausea and vomiting: a review of the clinical evidence Academic Article
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Safety Outcomes in Meta-analyses of Phase 2 vs Phase 3 Randomized Trials Academic Article
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Seeking informed consent to cancer clinical trials: Academic Article
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Single-agent Taxane Versus Taxane-containing Combination Chemotherapy as Salvage Therapy for Advanced Urothelial Carcinoma. Academic Article
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Stopping rules employing response rates, time to progression, and early progressive disease for phase II oncology trials Academic Article
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Survival outcomes and clinical benefit in patients with acute myeloid leukemia treated with glasdegib and low-dose cytarabine according to response to therapy Academic Article
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Systematic Chemotherapy for Inoperable, Locally Advanced, Recurrent, or Metastatic Uterine Leiomyosarcoma: A Systematic Review Academic Article
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Systemic adjuvant therapy for adult patients at high risk for recurrent melanoma: A systematic review Academic Article
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Systemic therapy for advanced uterine sarcoma: A systematic review of the literature Academic Article
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The Role of Gemcitabine in the Treatment of Cholangiocarcinoma and Gallbladder Cancer: A Systematic Review Academic Article
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The use of chemotherapy in patients with advanced malignant pleural mesothelioma: a systematic review and practice guideline. Academic Article
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Treatment Strategies in Elderly Patients with Aggressive Histology Lymphoma Academic Article
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Treatment of Multiple Myeloma: ASCO and CCO Joint Clinical Practice Guideline Academic Article
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[18F]DCFPyL PET-MRI/CT for unveiling a molecularly defined oligorecurrent prostate cancer state amenable for curative-intent ablative therapy: study protocol for a phase II trial Academic Article