BRCA1 Protein Concept

subject area of

• A combined analysis of outcome following breast cancer: differences in survival based on BRCA1/BRCA2 mutation status and administration of adjuvant treatment  Journal Articles
• ATM and CDK2 control chromatin remodeler CSB to inhibit RIF1 in DSB repair pathway choice  Journal Articles
• An evaluation of memory and attention in BRCA mutation carriers using an online cognitive assessment tool  Journal Articles
• BRCA1 is a novel target to improve endothelial dysfunction and retard atherosclerosis  Journal Articles
• Bilateral Oophorectomy and All-Cause Mortality in Women With BRCA1 and BRCA2 Sequence Variations  Journal Articles
• Bilateral Oophorectomy and the Risk of Breast Cancer in BRCA1 Mutation Carriers: A Reappraisal  Journal Articles
• Breast cancer risk after age 60 among BRCA1 and BRCA2 mutation carriers  Journal Articles
• Breastfeeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers  Journal Articles
• Breastfeeding and the risk of epithelial ovarian cancer among women with a BRCA1 or BRCA2 mutation  Journal Articles
• CSB interacts with BRCA1 in late S/G2 to promote MRN- and CtIP-mediated DNA end resection  Journal Articles
• Cdk-dependent phosphorylation regulates TRF1 recruitment to PML bodies and promotes C-circle production in ALT cells  Journal Articles
• Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53  Journal Articles
• Clinical–pathologic significance of cancer stem cell marker expression in familial breast cancers  Journal Articles
• Cockayne syndrome group B protein regulates fork restart, fork progression and MRE11-dependent fork degradation in BRCA1/2-deficient cells  Journal Articles
• Contraceptive use and the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation  Journal Articles
• Cyclin E expression in breast cancer: predicting germline BRCA1 mutations, prognosis and response to treatment  Journal Articles
• EMSY and CCND1 amplification in familial breast cancer: from the Ontario site of the Breast Cancer Family Registry  Journal Articles
• Evolution of genetic assessment for BRCA-associated gynaecologic malignancies: a Canadian multisociety roadmap  Journal Articles
• Gain of function mutant p53 proteins cooperate with E2F4 to transcriptionally downregulate RAD17 and BRCA1 gene expression  Journal Articles
• Hormonal Contraception and Breast Cancer Risk for Carriers of Germline Mutations in BRCA1 and BRCA2.  Journal Articles
• Hormone Replacement Therapy After Oophorectomy and Breast Cancer Risk Among BRCA1 Mutation Carriers  Journal Articles
• Individual and family characteristics associated with protein truncating BRCA1 and BRCA2 mutations in an Ontario population based series from the Cooperative Family Registry for Breast Cancer Studies  Journal Articles
• Interaction of p14^ARF with Brca1 in cancer cell lines and primary breast cancer  Journal Articles
• Kaiso depletion attenuates the growth and survival of triple negative breast cancer cells  Journal Articles
• Kaiso mediates transcription and RNA splicing in colorectal carcinoma: role of BRCA1 in the Kaiso enhanceosome.  Journal Articles
• Linkage analysis of 26 Canadian breast and breast-ovarian cancer families  Journal Articles
• MRI Surveillance and Breast Cancer Mortality in Women With BRCA1 and BRCA2 Sequence Variations  Journal Articles
• Mainstream Model of Genetic Testing for Prostate Cancer at a Large Tertiary Cancer Centre  Journal Articles
• Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2  Journal Articles
• NR1D1 Recruitment to Sites of DNA Damage Inhibits Repair and Is Associated with Chemosensitivity of Breast Cancer  Journal Articles
• Olaparib Efficacy in Patients with Metastatic Castration-resistant Prostate Cancer and BRCA1, BRCA2, or ATM Alterations Identified by Testing Circulating Tumor DNA  Journal Articles
• Olaparib combined with chemotherapy for recurrent platinum-sensitive ovarian cancer: a randomised phase 2 trial  Journal Articles
• Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: a phase 2, multicentre, open-label, non-randomised study  Journal Articles
• Oophorectomy and risk of contralateral breast cancer among BRCA1 and BRCA2 mutation carriers  Journal Articles
• Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2  Journal Articles
• Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer  Journal Articles
• Parity, breastfeeding, and the risk of early-onset breast cancer in women with a BRCA1 pathogenic variant.  Journal Articles
• Phosphorylated (pT371)TRF1 is recruited to sites of DNA damage to facilitate homologous recombination and checkpoint activation  Journal Articles
• Physical Activity During Adolescence and Early-adulthood and Ovarian Cancer Among Women with a BRCA1 or BRCA2 Mutation  Journal Articles
• Practice guidelines for BRCA1/2 tumour testing in ovarian cancer  Journal Articles
• Prognosis of BRCA-associated breast cancer: a summary of evidence  Journal Articles
• Prophylactic oophorectomy in Ontario.  Journal Articles
• Prospective study of high-risk, BRCA1/2-mutation negative women: the ‘negative study’  Journal Articles
• Recognizing BRCA gene mutation risk subsequent to breast cancer diagnosis in southwestern Ontario.  Journal Articles
• Risk-reducing mastectomy and breast cancer mortality in women with a BRCA1 or BRCA2 pathogenic variant: an international analysis  Journal Articles
• Should platinum-based chemotherapy be preferred for germline BReast CAncer genes (BRCA) 1 and 2-mutated pancreatic ductal adenocarcinoma (PDAC) patients? A systematic review and meta-analysis  Journal Articles
• Tamoxifen May Be an Effective Adjuvant Treatment for BRCA1-Related Breast Cancer Irrespective of Estrogen Receptor Status  Journal Articles
• Tamoxifen and the risk of breast cancer in women with a BRCA1 or BRCA2 mutation  Journal Articles
• The Role of Endogenous Hormones in the Etiology and Prevention of Breast Cancer: The Epidemiological Evidence  Conferences
• The incidence of leukaemia in women with BRCA1 and BRCA2 mutations: an International Prospective Cohort Study  Journal Articles
• The risks of cancer in older women with BRCA pathogenic variants: How far have we come?  Journal Articles
• Treatment of infertility does not increase the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation  Journal Articles
• Tumor protein expression of the DNA repair gene BRCA1 and lethal prostate cancer  Journal Articles
• Weight Gain and the Risk of Ovarian Cancer in BRCA1 and BRCA2 Mutation Carriers  Conferences