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Oophorectomy and risk of contralateral breast...
Journal article

Oophorectomy and risk of contralateral breast cancer among BRCA1 and BRCA2 mutation carriers

Abstract

PurposeFollowing a diagnosis of breast cancer, BRCA mutation carriers face an increased risk of developing a second (contralateral) cancer in the unaffected breast. It is important to identify predictors of contralateral cancer in order to make informed decisions about bilateral mastectomy. The impact of bilateral salpingo-oophorectomy (i.e., oophorectomy) on the risk of developing contralateral breast cancer is unclear. Thus, we conducted a …

Authors

Kotsopoulos J; Lubinski J; Lynch HT; Tung N; Armel S; Senter L; Singer CF; Fruscio R; Couch F; Weitzel JN

Journal

Breast Cancer Research and Treatment, Vol. 175, No. 2, pp. 443–449

Publisher

Springer Nature

Publication Date

June 2019

DOI

10.1007/s10549-019-05162-7

ISSN

0167-6806