Journal article
ERM is required for transcriptional control of the spermatogonial stem cell niche
Abstract
Division of spermatogonial stem cells1 produces daughter cells that either maintain their stem cell identity or undergo differentiation to form mature sperm. The Sertoli cell, the only somatic cell within seminiferous tubules, provides the stem cell niche through physical support and expression of surface proteins and soluble factors2,3. Here we show that the Ets related molecule4 (ERM) is expressed exclusively within Sertoli cells in the …
Authors
Chen C; Ouyang W; Grigura V; Zhou Q; Carnes K; Lim H; Zhao G-Q; Arber S; Kurpios N; Murphy TL
Journal
Nature, Vol. 436, No. 7053, pp. 1030–1034
Publisher
Springer Nature
Publication Date
August 2005
DOI
10.1038/nature03894
ISSN
0028-0836